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acknowledge support from the Laboratoire d'Excellence Integrative Biology of Emerging Infectious Diseases (grant no. ANR-10-LABX-62-IBEID) and the ANR under the "Investments for the Future" program (grant no. ANR-10-IAHU-01). A.A. acknowledges support from the Fondation pour la Recherche Médicale (grant no. DMI20091117308), Acknowledgments: We thank all members of the SCAHU platform and Lore Dubesset for technical assistance. Funding: This work was ,