Studies on the isolation of the factor responsible for tissue injury in inflammation, Science, vol.97, pp.165-172, 1943. ,
Temperature-elevating effect of a substance obtained from polymorphonuclear leucocytes, J Clin Invest, vol.27, p.524, 1948. ,
Studies on the pathogenesis of fever. II. Identification of an endogenous pyrogen in the blood stream following the injection of typhoid vaccine, J Exp Med, vol.102, pp.499-516, 1955. ,
From supernatants to cytokines: a personal view on the early history of IL-1, IL-1Ra, TNF and its inhibitor in rheumatology, Arthritis Res Ther, vol.20, pp.1-6, 2018. ,
Interleukin-1, Cytokine Growth Factor Rev, vol.8, pp.253-65, 1997. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01721887
IL-1: discoveries, controversies and future directions, Eur J Immunol, vol.40, pp.599-606, 2010. ,
Interleukin-1 family cytokines in liver diseases, Mediators Inflamm, p.630265, 2015. ,
Overview of the IL-1 family in innate inflammation and acquired immunity, Immunol Rev, vol.281, pp.8-27, 2018. ,
Interleukin-1 and related cytokines in the regulation of inflammation and immunity, Immunity, vol.50, pp.778-95, 2019. ,
IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity, Nature, vol.551, pp.110-114, 2017. ,
Tuning inflammation and immunity by the negative regulators IL-1R2 and IL-1R8, Immunol Rev, vol.281, pp.233-280, 2018. ,
The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'?, PLoS ONE, vol.3, pp.1-8, 2008. ,
Interleukin-33 (IL-33): a nuclear cytokine from the IL-1 family, Immunol Rev, vol.281, pp.154-68, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02363721
Activated mast cells synthesize and release soluble ST2-a decoy receptor for IL-33, Eur J Immunol, vol.45, pp.3034-3078, 2015. ,
Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation, J Biol Chem, vol.282, pp.26369-80, 2007. ,
IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system, J Clin Invest, vol.117, pp.1538-1587, 2007. ,
Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation, J Autoimmun, vol.55, pp.33-41, 2014. ,
Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation, Proc Natl Acad Sci, vol.107, pp.2574-2583, 2010. ,
Metabolic induction of trained immunity through the mevalonate pathway, Cell, vol.172, pp.135-181, 2018. ,
Modulation of myelopoiesis progenitors is an integral component of trained immunity, Cell, vol.172, pp.147-61, 2018. ,
The role of the interleukin-1 family in trained immunity, Immunol Rev, vol.281, pp.28-39, 2018. ,
The Nlrp3 inflammasome suppresses colorectal cancer metastatic growth in the liver by promoting natural killer cell tumoricidal activity, Immunity, vol.43, pp.751-63, 2015. ,
NK cell responses redefine immunological memory, J Immunol, vol.197, pp.2963-70, 2016. ,
Cutting edge: stage-specific requirement of IL-18 for antiviral NK cell expansion, J Immunol, vol.194, pp.1408-1420, 2015. ,
IL-33 receptor ST2 amplifies the expansion of NK cells and enhances host defense during mouse cytomegalovirus infection, J Immunol, vol.194, pp.5948-52, 2015. ,
Cytokine activation induces human memory-like NK cells, Blood, vol.120, pp.4751-60, 2012. ,
SIGIRR promotes resistance against Pseudomonas aeruginosa keratitis by down-regulating type-1 immunity and IL-1R1 and TLR4 signaling, J Immunol, vol.177, pp.548-56, 2006. ,
Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection, Infect Immun, vol.80, pp.100-109, 2012. ,
High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity, Oncotarget, vol.8, pp.49470-83, 2017. ,
A prominent role of interleukin-18 in acetaminophen-induced liver injury advocates its blockage for therapy of hepatic necroinflammation, Front Immunol, vol.9, pp.1-7, 2018. ,
Inherited IL-18BP deficiency in human fulminant viral hepatitis, J Exp Med, vol.216, pp.1777-90, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-02359432
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation, J Exp Med, vol.201, pp.233-273, 2005. ,
The role of inflammasomederived IL-1 in driving IL-17 responses, J Leukoc Biol, vol.93, pp.489-97, 2013. ,
A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis, J Exp Med, vol.203, pp.1685-91, 2006. ,
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity, Immunity, vol.31, pp.331-372, 2009. ,
A distinct function of regulatory T cells in tissue protection, Cell, vol.162, pp.1078-89, 2015. ,
IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions, Proc Natl Acad Sci, vol.112, pp.10762-10769, 2015. ,
The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production, Eur J Immunol, vol.39, pp.1046-55, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00676402
IL-33 amplifies both Th1-and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells, Int Immunol, vol.20, pp.1019-1049, 2008. ,
Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection, Immunity, vol.42, pp.566-79, 2015. ,
The alarmin interleukin-33 drives protective antiviral CD8+ T cell responses, Science, vol.335, pp.984-993, 2012. ,
A natural protective function of invariant NKT cells in a mouse model of innate-cell-driven lung inflammation, Eur J Immunol, vol.41, pp.299-305, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00539574
Endogenous IL-33 contributes to kidney ischemia-reperfusion injury as an alarmin, J Am Soc Nephrol, vol.29, pp.1272-88, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01929544
The impact of invariant NKT cells in sterile inflammation: the possible contribution of the alarmin/cytokine IL-33, Front Immunol, vol.9, p.2308, 2018. ,
URL : https://hal.archives-ouvertes.fr/inserm-02509353
The alarmin concept applied to human renal transplantation: evidence for a differential implication of HMGB1 and IL-33, PLoS ONE, vol.9, p.88742, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01928093
Novel immunomodulatory cytokine regulates inflammation, diabetes, and obesity to protect from diabetic nephropathy, Front Pharmacol, vol.10, p.572, 2019. ,
Stromal cells maintain immune cell homeostasis in adipose tissue via production of interleukin-33, Sci Immunol, vol.4, p.416, 2019. ,
Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors, Sci Immunol, vol.4, p.3658, 2019. ,
A nonimmune function of T cells in promoting lung tumor progression, J Exp Med, vol.214, pp.3565-75, 2017. ,
Western diet triggers NLRP3-dependent innate immune reprogramming, Cell, vol.172, pp.162-75, 2018. ,
BCG educates hematopoietic stem cells to generate protective innate immunity against tuberculosis, Cell, vol.172, pp.176-90, 2018. ,
NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis, Eur J Immunol, vol.41, pp.2341-2349, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00681990
Detection and characterization of IL-1 receptor antagonist in tissues from healthy rabbits: IL-1 receptor antagonist is probably involved in health, Cytokine, vol.9, pp.307-322, 1997. ,
Immunological and inflammatory functions of the interleukin-1 family, Annu Rev Immunol, vol.27, pp.519-50, 2009. ,
Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice, Hepatology, vol.56, pp.1468-78, 2012. ,
Acute liver failure, N Engl J Med, vol.369, pp.2525-2559, 2013. ,
Fulminant hepatic failure: etiology and indications for liver transplantation, Nephrol Dial Transplant, pp.5-8, 2007. ,
Hepatocyte necrosis induced by oxidative stress and IL-1? release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis, Cancer Cell, vol.14, pp.156-65, 2008. ,
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells, Nat Med, vol.13, pp.851-857, 2007. ,
Interleukin-1? and interleukin-1? play a central role in the pathogenesis of fulminant hepatic failure in mice, PLoS ONE, vol.12, p.184084, 2017. ,
Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein, J Clin Invest, vol.99, pp.2930-2970, 1997. ,
Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from macrophages causes acute liver injury in mice, Immunity, vol.11, pp.80111-80120, 1999. ,
Contribution of hepatic stellate cells and matrix metalloproteinase 9 in acute liver failure, Liver Int, vol.28, pp.959-71, 2008. ,
A bioartificial liver device secreting interleukin-1 receptor antagonist for the treatment of hepatic failure in rats, J Surg Res, vol.137, pp.130-170, 2007. ,
Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of macrophage activation syndrome: reanalysis of a prior phase III trial *, Crit Care Med, vol.44, pp.275-81, 2016. ,
IL-18 accounts for both TNF-alpha-and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice, J Immunol, vol.159, pp.3961-3968, 1997. ,
Severe hepatic injury in interleukin 18 (IL-18) transgenic mice: a key role for IL-18 in regulating hepatocyte apoptosis in vivo, Gut, vol.53, pp.392-400, 2004. ,
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome, J Clin Invest, vol.119, pp.305-319, 2009. ,
IL-33 signalling in liver immune cells enhances druginduced liver injury and inflammation, Inflamm Res, vol.67, pp.77-88, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02126492
Application of IL-36 receptor antagonist weakens CCL20 expression and impairs recovery in the late phase of murine acetaminophen-induced liver injury, Sci Rep, vol.5, pp.1-7, 2015. ,
Pathogenic mouse hepatitis virus or poly(I:C) induce IL-33 in hepatocytes in murine models of hepatitis, PLoS ONE, vol.8, pp.1-10, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-00874120
ASC/caspase-1/IL-1? signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury, Hepatology, vol.58, pp.351-62, 2013. ,
Activation of NLRP3 and AIM2 inflammasomes in Kupffer cells in hepatic ischemia/reperfusion, FEBS J, vol.282, pp.259-70, 2015. ,
NLRP3 regulates neutrophil functions and contributes to hepatic ischemiareperfusion injury independently of inflammasomes, J Immunol, vol.192, pp.4342-51, 2014. ,
Interaction of neutrophils with macrophages promotes IL-1? maturation and contributes to hepatic ischemia-reperfusion injury, J Immunol, vol.199, pp.3306-3321, 2017. ,
IL-33 exacerbates liver sterile inflammation by amplifying neutrophil extracellular trap formation, J Hepatol, vol.68, pp.130-139, 2017. ,
Sulfatide-mediated activation of type II natural killer T cells prevents hepatic ischemic reperfusion injury in mice, Gastroenterology, vol.140, pp.646-55, 2011. ,
Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells, J Gastroenterol Hepatol, vol.27, pp.1609-1625, 2012. ,
Enhanced tumour necrosis factor and interleukin-1 in fulminant hepatic failure, Lancet, vol.2, pp.90006-90008, 1988. ,
Circulating proinflammatory cytokines (IL-1 beta, TNF-alpha, and IL-6) and IL-1 receptor antagonist (IL-1Ra) in fulminant hepatic failure and acute hepatitis, Clin Exp Immunol, vol.98, pp.71-78, 1994. ,
Proinflammatory interleukin-18 and Caspase-1 serum levels in liver failure are unaffected by MARS treatment, Dig Liver Dis, vol.41, pp.417-440, 2009. ,
Upregulation of interleukin 33 and soluble ST2 serum levels in liver failure, J Surg Res, vol.163, pp.79-83, 2010. ,
Innatelike cytotoxic function of bystander-activated CD8+ T cells is associated with liver injury in acute hepatitis A, Immunity, vol.48, pp.161-73, 2018. ,
Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice, J Hepatol, vol.63, pp.1147-55, 2015. ,
IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice, J Clin Invest, vol.122, pp.3476-89, 2012. ,
Invariant NKT cells promote alcohol-induced steatohepatitis through interleukin-1? in mice, J Hepatol, vol.62, pp.1311-1319, 2015. ,
Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression, Gut, vol.68, pp.708-728, 2019. ,
Plasma levels of soluble ST2, but not IL-33, correlate with the severity of alcoholic liver disease, J Cell Mol Med, vol.23, pp.887-97, 2018. ,
IL-1 receptor like 1 protects against alcoholic liver injury by limiting NF-?B activation in hepatic macrophages, J Hepatol, vol.68, pp.109-126, 2018. ,
Inhibition of type I natural killer T cells by retinoids or following sulfatidemediated activation of type II natural killer T cells attenuates alcoholic liver disease in mice, Hepatology, vol.61, pp.1357-69, 2015. ,
Invariant natural killer T cells contribute to chronic-plus-binge ethanol-mediated liver injury by promoting hepatic neutrophil infiltration, Cell Mol Immunol, vol.13, pp.206-222, 2016. ,
How to diagnose NAFLD in 2016, J Hepatol, vol.65, pp.643-647, 2016. ,
The epidemiology of non-alcoholic fatty liver disease, Liver Int, vol.37, pp.81-85, 2017. ,
, EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease, European Association for the Study of the Liver (EASL), vol.59, pp.1121-1161, 2016.
The pathogenesis of nonalcoholic fatty liver disease: interplay between diet, gut microbiota, and genetic background, Gastroenterol Res Pract, p.2862173, 2016. ,
IL-1 Signaling in obesity-induced hepatic lipogenesis and steatosis, PLoS ONE, vol.9, p.107265, 2014. ,
Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice, Hepatology, vol.57, pp.577-89, 2013. ,
Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells, Hepatology, vol.54, pp.133-177, 2011. ,
Adipose and liver expression of interleukin (IL)-1 family members in morbid obesity and effects of weight loss, Mol Med Camb Mass, vol.17, pp.840-845, 2011. ,
Hepatic leukocyte recruitment in response to time-limited expression of TNF-? and IL-1?, Am J Physiol-Gastrointest Liver Physiol, vol.293, pp.663-72, 2007. ,
Interleukin-1 and inflammasomes in alcoholic liver disease/acute alcoholic hepatitis and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis, Hepatology, vol.64, pp.955-65, 2016. ,
Lack of interleukin-1? or interleukin-1? inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice, J Hepatol, vol.55, pp.1086-94, 2011. ,
Interleukin-1?-induced insulin resistance in adipocytes through downregulation of insulin receptor substrate-1 expression, Endocrinology, vol.148, pp.241-51, 2007. ,
URL : https://hal.archives-ouvertes.fr/inserm-00139856
Interleukin-1beta may mediate insulin resistance in liver-derived cells in response to adipocyte inflammation, Endocrinology, vol.151, pp.4247-56, 2010. ,
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling, Nat Immunol, vol.12, pp.408-423, 2011. ,
IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions, J Exp Med, vol.198, pp.877-88, 2003. ,
Deficiency of interleukin-1 receptor antagonist deteriorates fatty liver and cholesterol metabolism in hypercholesterolemic mice, J Biol Chem, vol.280, pp.7002-7011, 2005. ,
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity, Nature, vol.482, pp.179-85, 2012. ,
Endogenous IL-33 has no effect on the progression of fibrosis during experimental steatohepatitis, Oncotarget, vol.8, pp.48563-74, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01578584
IL-33 treatment attenuated diet-induced hepatic steatosis but aggravated hepatic fibrosis, Oncotarget, vol.7, pp.1-13, 2016. ,
Galectin-3 ablation enhances liver steatosis, but attenuates inflammation and IL-33-dependent fibrosis in obesogenic mouse model of nonalcoholic steatohepatitis, Mol Med Camb Mass, vol.21, pp.453-65, 2015. ,
Crucial role of IL-4/STAT6 in T cell-mediated hepatitis: up-regulating eotaxins and IL-5 and recruiting leukocytes, J Immunol, vol.171, pp.3233-3277, 2003. ,
Suppression of concanavalin Ainduced hepatitis in IFN-gamma(-/-) mice, but not in TNF-alpha(-/-) mice: role for IFN-gamma in activating apoptosis of hepatocytes, J Immunol, vol.159, pp.1418-1446, 1997. ,
The Pro-Th1 cytokine IL-12 enhances IL-4 production by invariant NKT cells: relevance for T cell-mediated hepatitis, J Immunol, vol.178, pp.5435-5477, 2007. ,
URL : https://hal.archives-ouvertes.fr/inserm-00314236
Critical contribution of liver natural killer T cells to a murine model of hepatitis, Proc Natl Acad Sci, vol.97, pp.5498-503, 2000. ,
TRAIL but not FasL and TNF?, regulates IL-33 expression in murine hepatocytes during acute hepatitis, Hepatology, vol.56, pp.2353-62, 2012. ,
Importance of Kupffer cells for T-cell-dependent liver injury in mice, Am J Pathol, vol.157, issue.10, pp.64804-64807, 2000. ,
NOD-like receptor protein 3 inflammasome-dependent IL-1? accelerated ConA-induced Hepatitis, Front Immunol, vol.9, p.758, 2018. ,
Ablation of interaction between IL-33 and ST2+ regulatory T cells increases immune cell-mediated hepatitis and activated NK cell liver infiltration, Am J Physiol Gastrointest Liver Physiol, vol.311, pp.313-336, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01366372
Protective role of IL-33/ST2 axis in Con A-induced hepatitis, J Hepatol, vol.56, pp.26-33, 2012. ,
A special population of regulatory T cells potentiates muscle repair, Cell, vol.155, pp.1282-95, 2013. ,
Hepatitis C virus induces interleukin-1 (IL-1 )/IL-18 in circulatory and resident liver macrophages, J Virol, vol.87, pp.12284-90, 2013. ,
IL-1? production through the NLRP3 Inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease, PLoS Pathog, vol.9, pp.1-13, 2013. ,
Ex vivo analysis of resident hepatic pro-inflammatory CD1d-reactive T cells and hepatocyte surface CD1d expression in hepatitis C, J Viral Hepat, vol.20, pp.556-65, 2013. ,
Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B, Gastroenterology, vol.138, pp.1-4, 2010. ,
iNKT cells in chronic HBV: a balancing act, Hepatol Int, vol.10, pp.535-542, 2016. ,
The dynamic changes of circulating invariant natural killer T cells during chronic hepatitis B virus infection, Hepatol Int, vol.10, pp.594-601, 2016. ,
Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice, J Virol, vol.76, pp.10702-10709, 2002. ,
DAMP molecular IL-33 augments monocytic inflammatory storm in hepatitis B-precipitated acuteon-chronic liver failure, Liver Int, vol.38, pp.229-267, 2018. ,
Relevance of serum interleukin-33 and ST2 levels and the natural course of chronic hepatitis B virus infection, BMC Infect Dis, vol.16, p.200, 2016. ,
Serum IL-33 levels are associated with liver damage in patients with chronic hepatitis C, Mediators Inflamm, p.819636, 2012. ,
Interleukin-1 participates in the progression from liver injury to fibrosis, Am J Physiol-Gastrointest Liver Physiol, vol.296, pp.1324-1355, 2009. ,
Interleukin-33 overexpression is associated with liver fibrosis in mice and humans, J Cell Mol Med, vol.14, pp.1726-1765, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-00660257
Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis, Immunity, vol.39, pp.357-71, 2013. ,
Gut microbiomemediated bile acid metabolism regulates liver cancer via NKT cells, Science, vol.360, p.5931, 2018. ,
CD1d-mediated stimulation of natural killer T cells selectively activates hepatic natural killer cells to eliminate experimentally disseminated hepatoma cells in murine liver, Int J Cancer, vol.106, pp.81-90, 2003. ,
A distinct IL-18-induced pathway to fully activate NK T lymphocytes independently from TCR engagement, J Immunol, vol.163, pp.5871-5877, 1999. ,
Enrichment of human CD4 + V?24/V?11 invariant NKT cells in intrahepatic malignant tumors, J Immunol, vol.182, pp.5140-51, 2009. ,
Tumoral expression of IL-33 inhibits tumor growth and modifies the tumor microenvironment through CD8 + T and NK cells, J Immunol, vol.194, pp.438-483, 2015. ,
Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth, Nat Immunol, vol.20, pp.257-64, 2019. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02063831
Alarmin IL-33 acts as an immunoadjuvant to enhance antigen-specific tumor immunity, Cancer Res, vol.74, pp.1789-800, 2014. ,
Hypoxia-inducible factor-1?/interleukin-1? signaling enhances hepatoma epithelialmesenchymal transition through macrophages in a hypoxic-inflammatory microenvironment, Hepatology, vol.67, pp.1872-89, 2018. ,
Interleukin-37 mediates the antitumor activity in hepatocellular carcinoma: role for CD57+ NK cells, Sci Rep, vol.4, p.5177, 2015. ,
IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling, Oncotarget, vol.7, pp.85079-96, 2016. ,
IL-37 induces autophagy in hepatocellular carcinoma cells by inhibiting the PI3K/AKT/mTOR pathway, Mol Immunol, vol.87, pp.132-172, 2017. ,
Role of IL-33 expression in oncogenesis and development of human hepatocellular carcinoma, Oncol Lett, vol.12, pp.429-465, 2016. ,
Detection of interleukin-33 in serum and carcinoma tissue from patients with hepatocellular carcinoma and its clinical implications, J Int Med Res, vol.40, pp.1654-61, 2012. ,
High serum levels of the interleukin-33 receptor soluble ST2 as a negative prognostic factor in hepatocellular carcinoma, Transl Oncol, vol.6, pp.311-319, 2013. ,
Inflammation and liver cancer: new molecular links, Ann N Y Acad Sci, vol.1155, pp.206-227, 2009. ,
Relevance of the NLRP3 inflammasome in the pathogenesis of chronic liver disease. Front Immunol, vol.8, p.1728, 2017. ,
Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors, Cell Death Dis, vol.10, p.128, 2019. ,
Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis, J Clin Invest, vol.109, pp.363-71, 2002. ,
Reduction in C-reactive protein indicates successful targeting of the IL-1/IL-6 axis resulting in improved survival in early stage multiple myeloma, Am J Hematol, vol.91, pp.571-575, 2016. ,
IL1 receptor antagonist controls transcriptional signature of inflammation in patients with metastatic breast cancer, Cancer Res, vol.78, pp.5243-58, 2018. ,
Antiinflammatory therapy with canakinumab for atherosclerotic disease, N Engl J Med, vol.377, pp.1119-1150, 2017. ,
A novel IL-2 and IL-33 hybrid cytokine, ameliorates renal injury, J Am Soc ,