R. Latorre, K. Castillo, W. Carrasquel-ursulaez, R. V. Sepulveda, F. Gonzalez-nilo et al., Molecular determinants of BK channel functional diversity and functioning, Physiol Rev, vol.97, pp.39-87, 2017.

M. T. Nelson, H. Cheng, M. Rubart, L. F. Santana, A. D. Bonev et al., Relaxation of arterial smooth muscle by calcium sparks, Science, vol.270, pp.633-637, 1995.

J. M. Price, J. F. Cabell, and A. Hellermann, Inhibition of camp mediated relaxation in rat coronary vessels by block of Ca 2+ activated K + channels, Life Sci, vol.58, pp.2225-2232, 1996.

V. A. Porter, A. D. Bonev, H. J. Knot, T. J. Heppner, A. S. Stevenson et al., Frequency modulation of Ca 2+ sparks is involved in regulation of arterial diameter by cyclic nucleotides, Am J Physiol, vol.274, pp.1346-1355, 1998.

G. C. Wellman, D. J. Nathan, C. M. Saundry, G. Perez, A. D. Bonev et al., Ca 2+ sparks and their function in human cerebral arteries, Stroke, vol.33, pp.802-808, 2002.

E. Wan, J. S. Kushner, S. Zakharov, X. W. Nui, N. Chudasama et al., Reduced vascular smooth muscle BK channel current underlies heart failure-induced vasoconstriction in mice, FASEB J, vol.27, pp.1859-1867, 2013.

A. M. Feldman, E. O. Weinberg, P. E. Ray, and B. H. Lorell, Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding, Circ Res, vol.73, pp.184-192, 1993.

W. J. Thompson and M. M. Appleman, Multiple cyclic nucleotide phosphodiesterase activities from rat brain, Biochemistry, vol.10, pp.311-316, 1971.

N. C. Nyborg, U. Baandrup, E. O. Mikkelsen, and M. J. Mulvany, Active, passive and myogenic characteristics of isolated rat intramural coronary resistance arteries, Pflugers Arch, vol.410, pp.664-670, 1987.

J. J. Singer and J. Walsh, Characterization of calcium-activated potassium channels in single smooth muscle cells using the patch-clamp technique, Pflugers Arch, vol.408, pp.98-111, 1987.

R. E. White, D. J. Darkow, and J. L. Lang, Estrogen relaxes coronary arteries by opening BKCa channels through a cgmp-dependent mechanism, Circ Res, vol.77, pp.936-942, 1995.

D. H. Maurice, D. Crankshaw, and R. J. Haslam, Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle, Eur J Pharmacol, vol.192, pp.235-242, 1991.

M. Bardou, F. Goirand, A. Bernard, P. Guerard, M. Gatinet et al., Relaxant effects of selective phosphodiesterase inhibitors on U46619 precontracted human intralobar pulmonary arteries and role of potassium channels, J Cardiovasc Pharmacol, vol.40, pp.153-161, 2002.

A. D. Rieg, R. Rossaint, E. Verjans, N. A. Maihofer, S. Uhlig et al., Levosimendan relaxes pulmonary arteries and veins in precision-cut lung slices -the role of K-channels, cAMP and cGMP, PLoS One, vol.8, p.66195, 2013.

H. Li, H. Hong-da, Y. K. Son, S. H. Na, W. K. Jung et al., Cilostazol induces vasodilation through the activation of Ca 2+ -activated K + channels in aortic smooth muscle, Vascul Pharmacol, vol.70, pp.15-22, 2015.

S. Khanamiri, E. Soltysinska, T. A. Jepps, B. H. Bentzen, P. S. Chadha et al., Contribution of Kv7 channels to basal coronary flow and active response to ischemia, Hypertension, vol.62, pp.1090-1097, 2013.

B. K. Mani, C. Robakowski, L. I. Brueggemann, L. L. Cribbs, A. Tripathi et al., Kv7.5 potassium channel subunits are the primary targets for PKA-dependent enhancement of vascular smooth muscle Kv7 currents, Mol Pharmacol, vol.89, pp.323-334, 2016.

S. Table, Abbreviations: ?K80: amplitude of contractile response to K80 solution; ?U46619: amplitude of contractile response to ?U46619; endo. (+) , endo. (-) : with functional or non-functional endothelium, respectively, Contraction level obtained in vascular reactivity experiments

D. Sousa, E. Veksler, V. Minajeva, A. Kaasik, A. Mateo et al., Subcellular creatine kinase alterations. Implications in heart failure, Circ Res, vol.85, pp.68-76, 1999.

F. Prunier, R. Gaertner, L. Louedec, J. B. Michel, J. J. Mercadier et al., Doppler echocardiographic estimation of left ventricular end-diastolic pressure after mi in rats, Am J Physiol Heart Circ Physiol, vol.283, pp.346-352, 2002.

L. E. Teichholz, T. Kreulen, M. V. Herman, and R. Gorlin, Problems in echocardiographic volume determinations: Echocardiographic-angiographic correlations in the presence or absence of asynergy, Am J Cardiol, vol.37, pp.7-11, 1976.

A. Galvez, G. Gimenez-gallego, J. P. Reuben, L. Roy-contancin, P. Feigenbaum et al., Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion buthus tamulus, J Biol Chem, vol.265, pp.11083-11090, 1990.

M. Gautier, J. M. Hyvelin, V. De-crescenzo, V. Eder, and P. Bonnet, Heterogeneous Kv1 function and expression in coronary myocytes from right and left ventricles in rats, Am J Physiol Heart Circ Physiol, vol.292, pp.475-482, 2007.

W. J. Thompson and M. M. Appleman, Multiple cyclic nucleotide phosphodiesterase activities from rat brain, Biochemistry, vol.10, pp.311-316, 1971.

T. Sudo, K. Tachibana, K. Toga, S. Tochizawa, Y. Inoue et al., Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity, Biochem Pharmacol, vol.59, pp.347-356, 2000.

T. C. Rich, T. E. Tse, J. G. Rohan, J. Schaack, and J. W. Karpen, In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as camp sensors, J Gen Physiol, vol.118, pp.63-78, 2001.

O. P. Hamill, A. Marty, E. Neher, B. Sakmann, and F. J. Sigworth, Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches, Pflugers Arch, vol.391, pp.85-100, 1981.

R. E. White, D. J. Darkow, and J. L. Lang, Estrogen relaxes coronary arteries by opening BKCa channels through a cgmp-dependent mechanism, Circ Res, vol.77, pp.936-942, 1995.

J. J. Singer and J. Walsh, Characterization of calcium-activated potassium channels in single smooth muscle cells using the patch-clamp technique, Pflugers Arch, vol.408, pp.98-111, 1987.

A. Abi-gerges, W. Richter, F. Lefebvre, P. Mateo, A. Varin et al., Decreased expression and activity of cAMP phosphodiesterases in cardiac hypertrophy and its impact on ?-adrenergic camp signals, Circ Res, vol.105, pp.784-792, 2009.
URL : https://hal.archives-ouvertes.fr/hal-00439324

B. Schwartzkopff, W. Motz, H. Frenzel, M. Vogt, S. Knauer et al., Structural and functional alterations of the intramyocardial coronary arterioles in patients with arterial hypertension, Circulation, vol.88, pp.993-1003, 1993.

S. S. Mangiafico, An r companion for the handbook of biological statistics, 2015.

J. H. Jaggar, V. A. Porter, W. J. Lederer, and M. T. Nelson, Calcium sparks in smooth muscle, Am J Physiol Cell Physiol, vol.278, pp.235-256, 2000.

J. L. Sutko, J. A. Airey, W. Welch, and L. Ruest, The pharmacology of ryanodine and related compounds, Pharmacol Rev, vol.49, pp.53-98, 1997.

A. Lagrutta, J. Wang, B. Fermini, and J. J. Salata, Novel, potent inhibitors of human Kv1.5 K + channels and ultrarapidly activating delayed rectifier potassium current, J Pharmacol Exp Ther, vol.317, pp.1054-1063, 2006.

P. Escoubas, S. Diochot, M. L. Celerier, T. Nakajima, and M. Lazdunski, Novel tarantula toxins for subtypes of voltage-dependent potassium channels in the Kv2 and Kv4 subfamilies
URL : https://hal.archives-ouvertes.fr/hal-00090915

, Mol Pharmacol, vol.62, pp.48-57, 2002.

D. Tsvetkov, M. Kassmann, J. Y. Tano, L. Chen, J. Schleifenbaum et al., Do Kv7.1 channels contribute to control of arterial vascular tone?, Br J Pharmacol, vol.174, pp.150-162, 2017.

N. B. Standen, J. M. Quayle, N. W. Davies, J. E. Brayden, Y. Huang et al., Hyperpolarizing vasodilators activate ATP-sensitive K + channels in arterial smooth muscle, Science, vol.245, pp.177-180, 1989.