J. M. Forbes and M. E. Cooper, Mechanisms of diabetic complications, Physiol Rev, vol.93, issue.1, pp.137-188, 2013.

F. B. Hu, J. E. Manson, M. J. Stampfer, G. Colditz, S. Liu et al., Diet, lifestyle, and the risk of type 2 diabetes mellitus in women, N Engl J Med, vol.345, issue.11, pp.790-797, 2001.

A. G. Tabák, C. Herder, W. Rathmann, E. J. Brunner, and M. Kivimäki, Prediabetes: a high-risk state for diabetes development, Lancet, vol.379, issue.9833, pp.60283-60292, 2012.

D. Thiebaud, E. Jacot, R. A. Defronzo, E. Maeder, E. Jequier et al., The effect of graded doses of insulin on total glucose uptake, glucose oxidation, and glucose storage in man, Diabetes, vol.31, issue.11, pp.957-963, 1982.

L. Salvado, X. Palomer, E. Barroso, and M. Vazquez-carrera, Targeting endoplasmic reticulum stress in insulin resistance, Trends Endocrinol Metab, vol.26, issue.8, pp.438-448, 2015.

N. K. Sharma, S. K. Das, A. K. Mondal, O. G. Hackney, W. S. Chu et al., Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects, J Clin Endocrinol Metab, vol.93, issue.11, pp.4532-4541, 2008.

G. Boden, X. Duan, C. Homko, E. J. Molina, W. Song et al., Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals, Diabetes, vol.57, issue.9, pp.2438-2444, 2008.

C. Xu, B. Bailly-maitre, and J. C. Reed, Endoplasmic reticulum stress: cell life and death decisions, The Journal of clinical investigation, vol.115, issue.10, pp.2656-2664, 2005.

M. Cnop, F. Foufelle, and L. A. Velloso, Endoplasmic reticulum stress, obesity and diabetes, Trends in Molecular Medicine, vol.18, issue.1, pp.59-68, 2012.

A. Boulinguiez, B. Staels, H. Duez, and S. Lancel, Mitochondria and endoplasmic reticulum_ Targets for a better insulin sensitivity in skeletal muscle? BBA -Molecular and, Cell Biology of Lipids, vol.1862, issue.9, pp.901-916, 2017.

H. L. Kammoun, H. Chabanon, I. Hainault, S. Luquet, C. Magnan et al., GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice, The Journal of clinical investigation, vol.119, issue.5, pp.1201-1215, 2009.

Y. Wang, L. Vera, W. H. Fischer, and M. Montminy, The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis, Nature, vol.460, issue.7254, pp.534-537, 2009.

T. Nakamura, M. Furuhashi, P. Li, H. Cao, G. Tuncman et al., Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis, Cell, vol.140, issue.3, pp.338-348, 2010.

U. Ozcan, Q. Cao, E. Yilmaz, A. Lee, N. N. Iwakoshi et al., Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes, Science, vol.306, issue.5695, pp.457-461, 2004.

R. Hage-hassan, I. Hainault, J. Vilquin, C. Samama, F. Lasnier et al., Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells, Diabetologia, vol.55, issue.1, pp.204-214, 2012.
URL : https://hal.archives-ouvertes.fr/hal-02450935

J. Rieusset, M. Chauvin, A. Durand, A. Bravard, F. Laugerette et al., Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance, Biochemical and biophysical research communications, vol.417, issue.1, pp.439-445, 2012.
URL : https://hal.archives-ouvertes.fr/inserm-00839433

H. Koh, T. Toyoda, M. M. Didesch, M. Lee, M. W. Sleeman et al., Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle, Nature Communications, vol.4, p.1871, 2013.

M. F. Gregor, L. Yang, E. Fabbrini, B. S. Mohammed, J. C. Eagon et al., Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss, Diabetes, vol.58, issue.3, pp.693-700, 2009.

S. Lopez-domenech, A. , Z. Iannantuoni, F. De-maranon, A. M. Rovira-llopis et al., Moderate weight loss attenuates chronic endoplasmic reticulum stress and mitochondrial dysfunction in human obesity, Mol Metab, vol.19, pp.24-33, 2019.

M. Matsuda and R. A. Defronzo, Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp, Diabetes Care, vol.22, issue.9, pp.1462-1470, 1999.

V. Raverdy, G. Baud, M. Pigeyre, H. Verkindt, F. Torres et al., Incidence and Predictive Factors of Postprandial Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass: A Five year Longitudinal Study, Ann Surg, vol.264, issue.5, pp.878-885, 2016.

K. I. Khalaf and H. Taegtmeyer, Clues from bariatric surgery: reversing insulin resistance to heal the heart, Curr Diab Rep, vol.13, issue.2, pp.245-251, 2013.

L. F. Meneghini, Impact of bariatric surgery on type 2 diabetes, Cell Biochem Biophys, vol.48, issue.2-3, pp.97-102, 2007.

S. Liong and M. Lappas, Endoplasmic reticulum stress regulates inflammation and insulin resistance in skeletal muscle from pregnant women, Molecular and cellular endocrinology, vol.425, pp.11-25, 2016.

D. Pincus, M. W. Chevalier, T. Aragon, E. Van-anken, S. E. Vidal et al., BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response, PLoS Biol, vol.8, issue.7, p.1000415, 2010.

T. Ijuin, N. Hatano, T. Hosooka, and T. Takenawa, Regulation of insulin signaling in skeletal muscle by PIP3 phosphatase, SKIP, and endoplasmic reticulum molecular chaperone glucose-regulated protein 78, Biochimica et biophysica acta, vol.1853, issue.12, pp.3192-3201, 2015.

J. Wu, J. L. Ruas, J. L. Estall, K. A. Rasbach, J. H. Choi et al., The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1?/ATF6? complex, Cell metabolism, vol.13, issue.2, pp.160-169, 2011.

T. Sasaki, A. Kuboyama, M. Mita, S. Murata, M. Shimizu et al., The exerciseinducible bile acid receptor Tgr5 improves skeletal muscle function in mice, J Biol Chem, vol.293, issue.26, pp.10322-10332, 2018.

X. Sun, W. Li, Y. Deng, B. Dong, Y. Sun et al., Hepatic conditional knockout of ATF6 exacerbates liver metabolic damage by repressing autophage through MTOR pathway, Biochem Biophys Res Commun, vol.505, issue.1, pp.45-50, 2018.

T. Zhou, Y. Cheng, W. Yan, X. Shi, X. Xu et al., TSPA as a novel ATF6alpha translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice, Biochem Biophys Res Commun, vol.499, issue.4, pp.948-953, 2018.

B. T. Bikman, D. Zheng, W. J. Pories, W. Chapman, J. R. Pender et al., Mechanism for improved insulin sensitivity after gastric bypass surgery, J Clin Endocrinol Metab, vol.93, issue.12, pp.4656-4663, 2008.

C. Vaurs, C. Dimeglio, L. Charras, Y. Anduze, C. Du-rieu et al., Determinants of changes in muscle mass after bariatric surgery, Diabetes Metab, vol.41, issue.5, pp.416-421, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01914876

C. S. Voican, A. Lebrun, S. Maitre, P. Lainas, K. Lamouri et al., Predictive score of sarcopenia occurrence one year after bariatric surgery in severely obese patients, PLoS One, vol.13, issue.5, p.197248, 2018.

M. Pourhassan, C. C. Gluer, P. Pick, W. Tigges, and M. J. Muller, Impact of weight loss-associated changes in detailed body composition as assessed by whole-body MRI on plasma insulin levels and homeostatis model assessment index, Eur J Clin Nutr, vol.71, issue.2, pp.212-218, 2017.

Y. Li, Y. Guo, J. Tang, J. Jiang, and Z. Chen, New insights into the roles of CHOP-induced apoptosis in ER stress, Acta Biochim Biophys Sin (Shanghai), vol.46, issue.8, pp.629-640, 2014.

J. Alter and E. Bengal, Stress-induced C/EBP homology protein (CHOP) represses MyoD transcription to delay myoblast differentiation, PLoS One, vol.6, issue.12, p.29498, 2011.

, FBG: Fasting Blood Glucose, G120: 2-hr glucose level after a 75g oral glucose tolerance test. Data are Mean (SEM) for normal distribution or Median, Supplementary Table 2 Metabolic features in the first cohort of glucose tolerant and intolerant non-diabetic obese patients BMI: Body Mass Index