F. Fischetti and F. Tedesco, Cross-talk between the complement system and endothelial cells in physiologic conditions and in vascular diseases, Autoimmunity, vol.39, pp.417-445, 2006.

M. J. Walport, Complement. First of two parts, N Engl J Med, vol.344, pp.1058-66, 2001.

D. Ricklin, G. Hajishengallis, K. Yang, and J. D. Lambris, Complement: a key system for immune surveillance and homeostasis, Nat Immunol, vol.11, pp.785-97, 2010.

D. Karpman, A. L. Ståhl, and I. Arvidsson, Complement interactions with blood cells, endothelial cells and microvesicles in thrombotic and inflammatory conditions, Adv Exp Med Biol, vol.865, pp.19-42, 2015.

K. N. Ekdahl, Y. Teramura, and O. A. Hamad, Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation, Immunol Rev, vol.274, pp.245-69, 2016.

R. W. Colman and A. H. Schmaier, Contact system: a vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes, Blood, vol.90, pp.3819-3862, 1997.

R. Kahn, T. Hellmark, and L. M. Leeb-lundberg, Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin, J Immunol, vol.182, pp.7906-7921, 2009.

L. M. Leeb-lundberg, F. Marceau, W. Müller-esterl, D. J. Pettibone, and B. L. Zuraw, International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences, Pharmacol Rev, vol.57, pp.27-77, 2005.

F. Bossi, E. I. Peerschke, B. Ghebrehiwet, and F. Tedesco, Cross-talk between the complement and the kinin system in vascular permeability, Immunol Lett, vol.140, pp.7-13, 2011.

M. Mossberg, A. L. Ståhl, and R. Kahn, C1-inhibitor decreases the release of vasculitislike chemotactic endothelial microvesicles, J Am Soc Nephrol, vol.28, pp.2472-81, 2017.

R. Kahn, H. Herwald, and W. Müller-esterl, Contact-system activation in children with vasculitis, Lancet, vol.360, pp.535-576, 2002.

C. G. Kallenberg and P. Heeringa, Complement system activation in ANCA vasculitis: a translational success story?, Mol Immunol, vol.68, pp.53-59, 2015.

M. Chen, D. Jayne, and M. H. Zhao, Complement in ANCA-associated vasculitis: mechanisms and implications for management, Nat Rev Nephrol, vol.13, pp.359-67, 2017.

D. Eleftheriou, M. J. Dillon, and P. A. Brogan, Advances in childhood vasculitis, Curr Opin Rheumatol, vol.21, pp.411-419, 2009.

R. A. Watts, A. Mahr, A. J. Mohammad, P. Gatenby, N. Basu et al., Classification, epidemiology and clinical subgrouping of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, Nephrol Dial Transplant, vol.30, pp.14-22, 2015.

M. Segelmark and J. Wieslander, IgG subclasses of antineutrophil cytoplasm autoantibodies (ANCA), Nephrol Dial Transplant, vol.8, pp.696-702, 1993.

M. Wester-trejo, L. A. Trouw, and I. M. Bajema, The role of complement in antineutrophil cytoplasmic antibody-associated vasculitis, Curr Opin Rheumatol, vol.31, pp.3-8, 2019.

R. Kahn, M. Mossberg, and A. L. Ståhl, Microvesicle transfer of kinin B1-receptors is a novel inflammatory mechanism in vasculitis, Kidney Int, vol.91, pp.96-105, 2017.

F. Dignat-george and C. M. Boulanger, The many faces of endothelial microparticles, Arterioscler Thromb Vasc Biol, vol.31, pp.27-33, 2011.

P. A. Brogan, V. Shah, and C. Brachet, Endothelial and platelet microparticles in vasculitis of the young, Arthritis Rheum, vol.50, pp.927-963, 2004.

P. A. Brogan and M. J. Dillon, Endothelial microparticles and the diagnosis of the vasculitides, Intern Med, vol.43, pp.1115-1124, 2004.

P. Kumpers, U. Erdbrugger, and M. Grossheim, Endothelial microparticles as a diagnostic aid in Churg-Strauss vasculitis-induced cardiomyopathy, Clin Exp Rheumatol, vol.26, pp.86-95, 2008.

L. A. Clarke, Y. Hong, and D. Eleftheriou, Endothelial injury and repair in systemic vasculitis of the young, Arthritis Rheum, vol.62, pp.1770-80, 2010.

J. Klein, J. Gonzalez, and S. Decramer, Blockade of the kinin B1 receptor ameloriates glomerulonephritis, J Am Soc Nephrol, vol.21, pp.1157-64, 2010.
URL : https://hal.archives-ouvertes.fr/inserm-00506236

J. C. Jennette, R. J. Falk, and P. A. Bacon, 2012 revised international Chapel Hill consensus conference nomenclature of vasculitides, Arthritis Rheum, vol.65, pp.1-11, 2013.

B. D. Cerrato, O. A. Carretero, B. Janic, H. E. Grecco, and M. M. Gironacci, Heteromerization between the Bradykinin B2 receptor and the angiotensin-(1-7) mas receptor: functional consequences, Hypertension, vol.68, pp.1039-1087, 2016.

R. Tati, A. C. Kristoffersson, and A. L. Ståhl, Complement activation associated with ADAMTS13 deficiency in human and murine thrombotic microangiopathy, J Immunol, vol.191, pp.2184-93, 2013.

D. Regoli, Neurohumoral regulation of precapillary vessels: the kallikrein-kinin system, J Cardiovasc Pharmacol, vol.6, pp.401-413, 1984.

B. Ghebrehiwet, A. P. Kaplan, K. Joseph, and E. I. Peerschke, The complement and contact activation systems: partnership in pathogenesis beyond angioedema, Immunol Rev, vol.274, pp.281-290, 2016.

C. Maas and T. Renne, Coagulation factor XII in thrombosis and inflammation, Blood, vol.131, pp.1903-1912, 2018.

S. De-maat, C. Tersteeg, E. Herczenik, and C. Maas, Tracking down contact activation -from coagulation in vitro to inflammation in vivo, Int J Lab Hematol, vol.36, pp.374-81, 2014.

G. Q. Xing, M. Chen, and G. Liu, Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis, J Clin Immunol, vol.29, pp.282-91, 2009.

K. Joseph, B. Ghebrehiwet, E. I. Peerschke, K. B. Reid, and A. P. Kaplan, Identification of the zincdependent endothelial cell binding protein for high molecular weight kininogen and factor XII: identity with the receptor that binds to the globular "heads" of C1q (gC1q-R), Proc Natl Acad Sci U S A, vol.93, pp.8552-8559, 1996.

S. Irmscher, N. Doring, and L. D. Halder, Kallikrein cleaves C3 and activates complement, J Innate Immun, vol.10, pp.94-105, 2018.

W. D. Campbell, E. Lazoura, N. Okada, and H. Okada, Inactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase N, Microbiol Immunol, vol.46, pp.131-135, 2002.

A. Kuoppala, K. A. Lindstedt, J. Saarinen, P. T. Kovanen, and J. O. Kokkonen, Inactivation of bradykinin by angiotensin-converting enzyme and by carboxypeptidase N in human plasma, Am J Physiol Heart Circ Physiol, vol.278, pp.1069-74, 2000.

K. D. Bhoola, N. L. Misso, A. Naran, and P. J. Thompson, Current status of tissue kallikrein inhibitors: importance in cancer, Curr Opin Investig Drugs, vol.8, pp.462-470, 2007.

S. V. Petersen, S. Thiel, L. Jensen, T. Vorup-jensen, C. Koch et al., Control of the classical and the MBL pathway of complement activation, Mol Immunol, vol.37, pp.803-814, 2000.

D. Noone, D. Hebert, and C. Licht, Pathogenesis and treatment of ANCA-associated vasculitis-a role for complement, Pediatr Nephrol, vol.33, pp.1-11, 2018.

H. Xiao, A. Schreiber, P. Heeringa, R. J. Falk, and J. C. Jennette, Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies, Am J Pathol, vol.170, pp.52-64, 2007.

S. J. Gou, J. Yuan, C. Wang, M. H. Zhao, and M. Chen, Alternative complement pathway activation products in urine and kidneys of patients with ANCA-associated GN, Clin J Am Soc Nephrol, vol.8, pp.1884-91, 2013.

Y. H. Yang, I. J. Tsai, C. J. Chang, Y. H. Chuang, H. Y. Hsu et al., The interaction between circulating complement proteins and cutaneous microvascular endothelial cells in the development of childhood Henoch-Schonlein Purpura, PLoS One, vol.10, p.120411, 2015.

M. Chen, M. R. Daha, and C. G. Kallenberg, The complement system in systemic autoimmune disease, J Autoimmun, vol.34, pp.276-86, 2010.

A. Schreiber, H. Xiao, J. C. Jennette, W. Schneider, F. C. Luft et al., C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis, J Am Soc Nephrol, vol.20, pp.289-98, 2009.

L. Daniel, F. Fakhouri, and D. Joly, Increase of circulating neutrophil and platelet microparticles during acute vasculitis and hemodialysis, Kidney Int, vol.69, pp.1416-1439, 2006.

G. Castellano, R. Melchiorre, and A. Loverre, Therapeutic targeting of classical and lectin pathways of complement protects from ischemia-reperfusion-induced renal damage, Am J Pathol, vol.176, pp.1648-59, 2010.

R. A. Montgomery, B. J. Orandi, and L. Racusen, Plasma-derived C1 esterase inhibitor for acute antibody-mediated rejection following kidney transplantation: results of a randomized double-blind placebo-controlled pilot study, Am J Transplant, vol.16, pp.3468-78, 2016.

T. Mcnearney, L. Ballard, T. Seya, and J. P. Atkinson, Membrane cofactor protein of complement is present on human fibroblast, epithelial, and endothelial cells, J Clin Invest, vol.84, pp.538-583, 1989.

A. S. Asch, T. Kinoshita, E. A. Jaffe, and V. Nussenzweig, Decay-accelerating factor is present on cultured human umbilical vein endothelial cells, J Exp Med, vol.163, pp.221-227, 1986.

K. K. Hamilton, J. Z. Rollins, S. Stewart, B. H. Sims, and P. J. , Regulatory control of the terminal complement proteins at the surface of human endothelial cells: neutralization of a C5b-9 inhibitor by antibody to CD59, Blood, vol.76, pp.2572-2579, 1990.

D. Jayne, A. N. Bruchfeld, and L. Harper, Randomized trial of C5a receptor inhibitor avacopan in ANCA-associated Vasculitis, J Am Soc Nephrol, vol.28, pp.2756-67, 2017.

R. Kettritz, Vasculitis: A CLEAR argument for targeting complement in ANCA vasculitis, Nat Rev Nephrol, vol.13, pp.448-50, 2017.