Dendrimers ended by non-symmetrical azadiphosphonate groups: Synthesis and immunological properties

Patrice Marchand; Laurent Griffe; Mary Poupot; Cédric-Olivier Turrin; Gérard Bacquet; Jean-Jacques Fournié; Jean Pierre Majoral; Rémy Poupot; Anne-Marie Caminade

doi:10.1016/j.bmcl.2009.03.003

Journal articles

Dendrimers ended by non-symmetrical azadiphosphonate groups: Synthesis and immunological properties

Patrice Marchand ¹ Laurent Griffe ¹ Mary Poupot ^{2, 3} Cédric-Olivier Turrin ¹ Gérard Bacquet ⁴ Jean-Jacques Fournié ^{2, 3} Jean Pierre Majoral ¹ Rémy Poupot ^{2, 3} Anne-Marie Caminade ¹

1 LCC - Laboratoire de chimie de coordination

2 INSERM U563 - CNRS UMR1037 - Centre de Physiopathologie de Toulouse-Purpan

3 UT3 - Université Toulouse III - Paul Sabatier

4 RHODIA - Centre de Recherches d'Aubervilliers

Abstract : The synthesis and characterization of new series of phosphorus-containing dendrimers ended by non-symmetrical azamonophosphonates, or azadiphosphonates, or azadiphosphonic acid salts are reported. The sodium salts of the non-symmetrical azadiphosphonic dendrimers are soluble in water. Their influence towards human immune blood cells is assayed ex vivo.

Document type :

Journal articles

Domain :

Life Sciences [q-bio] / Human health and pathology / Hematology

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https://www.hal.inserm.fr/inserm-02472251
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Submitted on : Monday, February 10, 2020 - 10:05:27 AM
Last modification on : Friday, June 4, 2021 - 4:46:05 PM

Dendrimers ended by non-symmetrical azadiphosphonate groups: Synthesis and immunological properties

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Dendrimers ended by non-symmetrical azadiphosphonate groups: Synthesis and immunological properties

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