S. Alexander, A. Mathie, and J. A. Peters, Guide to Receptors and Channels (GRAC), 4th edn, Br J Pharmacol, vol.158, pp.1-254, 2009.

M. J. Banfield, R. L. Naylor, A. G. Robertson, S. J. Allen, D. Dawbarn et al., Specificity in Trk receptor: neurotrophin interactions: the crystal structure of TrkB-d5 in complex with neurotrophin-4/5, vol.9, pp.1191-1199, 2001.

M. Benedetti, A. Levi, and M. V. Chao, Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness, Proc Natl Acad Sci, vol.90, pp.7859-7863, 1993.

A. Cattaneo, S. Capsoni, E. Margotti, M. Righi, E. Kontsekova et al., Functional blockade of tyrosine kinase A in the rat basal forebrain by a novel antagonistic anti-receptor monoclonal antibody, J Neurosci, vol.19, pp.9687-9697, 1999.

M. Cazorla, A. Jouvenceau, C. Rose, J. P. Guilloux, C. Pilon et al., Cyclotraxin-B, the first highly potent and selective TrkB inhibitor, has anxiolytic properties in mice, PLoS One, vol.5, p.9777, 2010.
URL : https://hal.archives-ouvertes.fr/inserm-02472181

M. V. Chao, Neurotrophins and their receptors: a convergence point for many signalling pathways, Nat Rev Neurosci, vol.4, pp.299-309, 2003.

M. V. Chao and B. L. Hempstead, p75 and Trk: a two-receptor system, Trends Neurosci, vol.18, pp.321-326, 1995.

Z. Y. Chen, D. Jing, K. G. Bath, A. Ieraci, T. Khan et al., Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior, Science, vol.314, pp.140-143, 2006.

D. O. Clary, G. Weskamp, L. R. Austin, and L. F. Reichardt, TrkA cross-linking mimics neuronal responses to nerve growth factor, Mol Biol Cell, vol.5, pp.549-563, 1994.

C. J. Desmet and D. S. Peeper, The neurotrophic receptor TrkB: a drug target in anti-cancer therapy?, Cell Mol Life Sci, vol.63, pp.755-759, 2006.

S. Douma, T. Van-laar, J. Zevenhoven, R. Meuwissen, E. Van-garderen et al., Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB, Nature, vol.430, pp.1034-1039, 2004.

N. Durany and J. Thome, Neurotrophic factors and the pathophysiology of schizophrenic psychoses, Eur Psychiatry, vol.19, pp.326-337, 2004.

T. R. Geiger and D. S. Peeper, The neurotrophic receptor TrkB in anoikis resistance and metastasis: a perspective, Cancer Res, vol.65, pp.7033-7036, 2005.

S. H. Green, R. E. Rydel, J. L. Connolly, and L. A. Greene, PC12 cell mutants that possess low-but not high-affinity nerve growth factor receptors neither respond to nor internalize nerve growth factor, J Cell Biol, vol.102, pp.830-843, 1986.

V. Guillemard, L. Ivanisevic, A. G. Garcia, V. Scholten, O. M. Lazo et al., An agonistic mAb directed to the TrkC receptor juxtamembrane region defines a trophic hot spot and interactions with p75 coreceptors, Dev Neurobiol, vol.70, pp.150-164, 2009.

B. L. Hempstead, D. Martin-zanca, D. R. Kaplan, L. F. Parada, and M. V. Chao, High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor, Nature, vol.350, pp.678-683, 1991.

E. J. Huang and L. F. Reichardt, Neurotrophins: roles in neuronal development and function, Annu Rev Neurosci, vol.24, pp.677-736, 2001.

E. J. Huang and L. F. Reichardt, Trk receptors: roles in neuronal signal transduction, Annu Rev Biochem, vol.72, pp.609-642, 2003.

L. L. Ilag, P. Lonnerberg, H. Persson, and C. F. Ibanez, Role of variable beta-hairpin loop in determining biological specificities in neurotrophin family, J Biol Chem, vol.269, pp.19941-19946, 1994.

N. Y. Ip, T. N. Stitt, P. Tapley, R. Klein, D. J. Glass et al., Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells, Neuron, vol.10, pp.137-149, 1993.

R. Klein, D. Conway, L. F. Parada, and M. Barbacid, The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain, Cell, vol.61, pp.647-656, 1990.

K. Kramer, W. Gerald, L. Lesauteur, H. U. Saragovi, and N. K. Cheung, , 1997.

, Monoclonal antibody to human Trk-A: diagnostic and therapeutic potential in neuroblastoma, Eur J Cancer, vol.33, pp.2090-2091

F. Lafont, M. Rouget, A. Triller, A. Prochiantz, and A. Rousselet, In vitro control of neuronal polarity by glycosaminoglycans, Development, vol.114, pp.17-29, 1992.

L. Lesauteur, S. Maliartchouk, L. Jeune, H. Quirion, R. Saragovi et al., Potent human p140-TrkA agonists derived from an anti-receptor monoclonal antibody, J Neurosci, vol.16, pp.1308-1316, 1996.

B. Lu, BDNF and activity-dependent synaptic modulation, Learn Mem, vol.10, pp.86-98, 2003.

B. Lu, P. T. Pang, and N. H. Woo, The yin and yang of neurotrophin action, Nat Rev Neurosci, vol.6, pp.603-614, 2005.

J. O. Mcnamara, Y. Z. Huang, and A. S. Leonard, Molecular signaling mechanisms underlying epileptogenesis, Sci STKE, p.12, 2006.

J. Mojsilovic-petrovic, G. B. Jeong, A. Crocker, A. Arneja, S. David et al., Protecting motor neurons from toxic insult by antagonism of adenosine A2a and Trk receptors, J Neurosci, vol.26, pp.9250-9263, 2006.

Y. Muragaki, N. Timothy, S. Leight, B. L. Hempstead, M. V. Chao et al., Expression of trk receptors in the developing and adult human central and peripheral nervous system, J Comp Neurol, vol.356, pp.387-397, 1995.

M. G. Murer, Q. Yan, and R. Raisman-vozari, Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease, Prog Neurobiol, vol.63, pp.71-124, 2001.

A. Nakagawara, C. G. Azar, N. J. Scavarda, and G. M. Brodeur, Expression and function of TRK-B and BDNF in human neuroblastomas, Mol Cell Biol, vol.14, pp.759-767, 1994.

E. J. Nestler, M. Barrot, R. J. Dileone, A. J. Eisch, S. J. Gold et al., Neurobiology of depression, Neuron, vol.34, pp.13-25, 2002.

M. Pattarawarapan and K. Burgess, Molecular basis of neurotrophin-receptor interactions, J Med Chem, vol.46, pp.5277-5291, 2003.

P. Perez, P. M. Coll, B. L. Hempstead, D. Martin-zanca, and M. V. Chao, NGF binding to the trk tyrosine kinase receptor requires the extracellular immunoglobulin-like domains, Mol Cell Neurosci, vol.6, pp.97-105, 1995.

S. Pezet and S. B. Mcmahon, Neurotrophins: mediators and modulators of pain, Annu Rev Neurosci, vol.29, pp.507-538, 2006.

M. M. Poo, Neurotrophins as synaptic modulators, Nat Rev Neurosci, vol.2, pp.24-32, 2001.

M. D. Qian, J. Zhang, X. Y. Tan, A. Wood, D. Gill et al., Novel agonist monoclonal antibodies activate TrkB receptors and demonstrate potent neurotrophic activities, J Neurosci, vol.26, pp.9394-9403, 2006.

M. D. Sadick, A. Galloway, D. Shelton, V. Hale, S. Weck et al., Analysis of neurotrophin/receptor interactions with a gD-flag-modified quantitative kinase receptor activation (gD.KIRA) enzyme-linked immunosorbent assay, Exp Cell Res, vol.234, pp.354-361, 1997.

G. Shaltiel, G. Chen, and H. K. Manji, Neurotrophic signaling cascades in the pathophysiology and treatment of bipolar disorder, Curr Opin Pharmacol, vol.7, pp.22-26, 2007.

C. Zuccato, A. Ciammola, D. Rigamonti, B. R. Leavitt, D. Goffredo et al., Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease, Science, vol.293, pp.493-498, 2001.