The Future of Cardiovascular Epidemiology, Circulation, vol.133, pp.2622-2633, 2016. ,
, World Health Organization. Cardiovascular diseases (CVDs), p.17, 2019.
Cardiac Fibrosis: The Fibroblast Awakens, Circ. Res, vol.118, pp.1021-1040, 2016. ,
Myocardial fibrosis in congenital and pediatric heart disease, vol.13, pp.1660-1664, 2017. ,
The pathogenesis of cardiac fibrosis, Cell Mol. Life Sci, vol.71, pp.549-574, 2014. ,
Novel Role for Osteopontin in Cardiac Fibrosis, Circ. Res, vol.102, pp.270-272, 2008. ,
Prognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events, Adv. Med. Sci, vol.63, pp.160-166, 2018. ,
Cardiac fibrosis: Potential therapeutic targets, Transl. Res, vol.209, pp.121-137, 2019. ,
Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease, Fibrogenesis Tissue Repair, vol.5, 2012. ,
The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis, J. Cell Mol. Med, vol.23, pp.4229-4243, 2019. ,
Osteopontin and wound healing in bone, Cells Tissues Organs, vol.194, pp.313-319, 2011. ,
Matricellular Proteins: New Molecular Targets To Prevent Heart Failure, Cardiovasc. Ther, vol.30, pp.198-209, 2011. ,
Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiomyocyte hypertrophy, PLoS ONE, vol.10, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-02519399
Role in extracellular matrix deposition and myocardial remodeling post-MI, J. Mol. Cell Cardiol, vol.48, pp.538-543, 2010. ,
Osteopontin RNA aptamer can prevent and reverse pressure overload-induced heart failure, Cardiovasc. Res, vol.113, pp.633-643, 2017. ,
Osteopontin expression is required for myofibroblast differentiation, Circ. Res, vol.102, pp.319-327, 2008. ,
At the cross-roads of myocyte survival and myocardial function, Life Sci, vol.118, pp.1-6, 2014. ,
Transformed mammalian cells secrete specific proteins and phosphoproteins, Cell, vol.16, pp.885-893, 1979. ,
Osteopontin in cardiovascular disease: A potential therapeutic target, Cardiol. Rev, vol.18, pp.125-131, 2010. ,
, Crit. Rev. Oral. Biol. Med, vol.11, pp.279-303, 2000.
Osteopontin isoforms differentially promote arteriogenesis in response to ischemia via macrophage accumulation and survival, Lab. Investig, vol.99, pp.331-345, 2019. ,
Targeting osteopontin, the silent partner of Na+/H+ exchanger isoform 1 in cardiac remodeling, J. Cell Physiol, vol.230, 2006. ,
Human osteopontin: Potential clinical applications in cancer (Review), Int. J. Mol. Med, vol.39, pp.1327-1337, 2017. ,
Osteopontin in Vascular Disease Friend or Foe?, Arterioscler. Thromb. Vasc. Biol, vol.39, pp.613-622, 2019. ,
Control of osteopontin signaling and function by post-translational phosphorylation and protein folding, J. Cell Biochem, vol.102, pp.912-924, 2007. ,
Plasma osteopontin levels in patients with dilated and hypertrophic cardiomyopathy, vol.44, pp.347-353, 2017. ,
Cooperative unfolding of compact conformations of the intrinsically disordered protein osteopontin, Biochemistry, vol.52, pp.5167-5175, 2013. ,
The multiple functions and mechanisms of osteopontin, Clin. Biochem, vol.59, pp.17-24, 2018. ,
Autocrine expression of osteopontin contributes to PDGF-mediated arterial smooth muscle cell migration, Cardiovasc. Res, vol.75, pp.738-747, 2007. ,
The role of osteopontin in inflammatory processes, J. Cell Commun. Signal, vol.3, pp.311-322, 2009. ,
NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival, J. Cell Biol, vol.141, pp.1083-1093, 1998. ,
N-terminal rather than full-length osteopontin or its C-terminal fragment is associated with carotid-plaque inflammation in hypertensive patients, Am. J. Hypertens, vol.26, pp.326-333, 2013. ,
Age-dependent functional crosstalk between cardiac fibroblasts and cardiomyocytes in a 3D engineered cardiac tissue, Acta Biomater, vol.55, pp.120-130, 2017. ,
Role of Matricellular Proteins in Cardiac Allograft Fibrosis, Cardiac Transplantation, pp.99-122, 2012. ,
Pathological role of serum-and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling, Circulation, vol.126, pp.2208-2219, 2012. ,
Myocardial osteopontin expression is associated with left ventricular hypertrophy, Circulation, vol.96, pp.3063-3071, 1997. ,
Osteopontin modulates myocardial hypertrophy in response to chronic pressure overload in mice, Hypertension, vol.44, pp.826-831, 2004. ,
Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy, Hypertension, vol.43, pp.1195-1201, 2004. ,
Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase, Physiol. Genom, vol.50, pp.332-342, 2018. ,
URL : https://hal.archives-ouvertes.fr/inserm-02468916
Na + /H + exchanger isoform 1 induced osteopontin expression in cardiomyocytes involves NFAT3/Gata4, Mol. Cell Biochem, vol.404, pp.211-220, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-02519417
Osteopontin regulates development and function of invariant natural killer T cells, Proc. Natl. Acad. Sci, vol.105, pp.15884-15889, 2008. ,
Elevated myocardial Na + /H + exchanger isoform 1 activity elicits gene expression that leads to cardiac hypertrophy, Physiol. Genom, vol.42, pp.374-383, 2010. ,
Sgk1 sensitivity of Na+/H+ exchanger activity and cardiac remodeling following pressure overload, Basic Res. Cardiol, vol.107, pp.1-15, 2012. ,
Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: Possible involvement of PKC-MAPK signaling pathway, Eur. J. Pharm. Sci, vol.47, pp.604-614, 2012. ,
Nuclear factor of activated T cells regulates osteopontin expression in arterial smooth muscle in response to diabetes-induced hyperglycemia, Arter. Thromb. Vasc. Biol, vol.30, pp.218-224, 2010. ,
, Osteopontin expression in cardiomyocytes induces dilated cardiomyopathy. Circ. Heart Fail, vol.3, pp.431-439, 2010.
Osteopontin and cardiovascular system, Mol. Cell Biochem, vol.300, pp.1-7, 2007. ,
Lack of osteopontin improves cardiac function in streptozotocin-induced diabetic mice, Am. J. Physiol. Heart Circ. Physiol, vol.292, pp.673-683, 2007. ,
Three in a Box: Understanding Cardiomyocyte, Fibroblast, and Innate Immune Cell Interactions to Orchestrate Cardiac Repair Processes, Front. Cardiovasc. Med, vol.6, 2019. ,
CD44 is critically involved in infarct healing by regulating the inflammatory and fibrotic response, J. Immunol, vol.180, pp.2625-2633, 2008. ,
Osteopontin-mediated myocardial fibrosis in heart failure: A role for lysyl oxidase?, Cardiovasc. Res, vol.99, pp.111-120, 2013. ,
Regulation of adverse remodelling by osteopontin in a genetic heart failure model, Eur Heart J, vol.33, pp.1954-1963, 2012. ,
Matricellular proteins in cardiac adaptation and disease, Physiol. Rev, vol.92, pp.635-688, 2012. ,
Association between osteopontin promoter variants and diastolic dysfunction in hypertensive heart in the Japanese population, Hypertens Res, vol.34, pp.1141-1146, 2011. ,
Osteopontin modulates angiotensin II-induced fibrosis in the intact murine heart, J. Am. Coll. Cardiol, vol.43, pp.1698-1705, 2004. ,
Deep Sequence Analysis of Gene Expression Identifies Osteopontin as a Downstream Effector of Integrin-Linked Kinase (ILK) in Cardiac-Specific ILK Knockout Mice, Circ. Heart Fail, vol.7, pp.184-193, 2014. ,
ERK1/2 and JNKs, but not p38 kinase, are involved in reactive oxygen species-mediated induction of osteopontin gene expression by angiotensin II and interleukin-1beta in adult rat cardiac fibroblasts, J. Cell Physiol, vol.198, pp.399-407, 2004. ,
Downregulating osteopontin reduces angiotensin II-induced inflammatory activation in vascular smooth muscle cells, Inflamm. Res, vol.58, pp.67-73, 2009. ,
Exaggerated left ventricular dilation and reduced collagen deposition after myocardial infarction in mice lacking osteopontin, Circ. Res, vol.88, pp.1080-1087, 2001. ,
Deletion of Osteopontin Enhances beta(2)-Adrenergic Receptor-Dependent Anti-Fibrotic Signaling in Cardiomyocytes, Int. J. Mol. Sci, vol.20, 1396. ,
Application of nanoparticle-based siRNA and CRISPR/Cas9 delivery systems in gene-targeted therapy, Nanomedicine, vol.14, pp.511-514, 2019. ,
Osteopontin is a strong predictor of incipient diabetic nephropathy, cardiovascular disease, and all-cause mortality in patients with type 1 diabetes, Diabetes Care, vol.37, pp.2593-2600, 2014. ,
Osteopontin predicts adverse right ventricular remodelling and dysfunction in pulmonary hypertension, Eur. J. Clin. Invest, vol.42, pp.933-942, 2012. ,
Plasma osteopontin levels in prediction of prognosis in acute myocardial infarction, Acta Cardiol, vol.66, pp.197-202, 2011. ,
Time-dependent changes in plasma osteopontin levels in patients with anterior-wall acute myocardial infarction after successful reperfusion: Correlation with left-ventricular volume and function, J. Lab. Clin. Med, vol.145, pp.33-40, 2005. ,
Plasma osteopontin reveals left ventricular reverse remodelling following cardiac resynchronization therapy in heart failure, Int. J. Cardiol, vol.153, pp.306-310, 2011. ,
, This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, © 2019 by the authors. Licensee MDPI