Skip to Main content Skip to Navigation
Journal articles

Comparison of echocardiographic indices of right ventricular systolic function and ejection fraction obtained with continuous thermodilution in critically ill patients

Abstract : BACKGROUND: Though echocardiographic evaluation assesses the right ventricular systolic function, which of the existing parameters best reflects the right ventricular ejection fraction (RVEF) in the critically ill patients is still uncertain. We aimed to determine the relationship between echocardiographic indices of right ventricular systolic function and RVEF. METHODS: Prospective observational study was conducted in a mixed Surgical Intensive Care Unit (Hôpital Lariboisière, Paris, France) from November 2017 to November 2018. All critically ill patients monitored with a pulmonary artery catheter were assessed. We collected echocardiographic indices of right ventricular function (tricuspid annular plane systolic excursion, TAPSE; peak systolic velocity of pulsed tissue Doppler at lateral tricuspid annulus, S'; fractional area change, FAC; right ventricular index of myocardial performance, RIMP; isovolumic acceleration, IVA; end-diastolic diameter ratio, EDDr) and compared them with the RVEF obtained from continuous volumetric pulmonary artery catheter. RESULTS: Twenty-five patients were analyzed. Admission diagnosis was acute heart failure in 11 patients and septic shock in 14 patients. Median age was 70 years [57-80], norepinephrine median dose was 0.29 μg/kg/min [0.14-0.50], median Sequential Organ Failure Assessment score was 12 [10-14], and mortality at day 28 was 56%. When compared to RVEF, TAPSE had the highest correlation coefficient (rho = 0.78, 95% CI 0.52 to 0.89, p < 0.001). S' was also correlated to RVEF (rho = 0.64, 95% CI 0.60 to 0.80, p = 0.001) whereas FAC, RIMP, IVA, and EDDr did not. TAPSE lower than 16 mm, S' lower than 11 cm/s, and EDDr higher than 1 were always associated with a reduced RVEF. CONCLUSIONS: We found that amongst indices of right ventricular systolic function, TAPSE and S' were well correlated with thermodilution-derived RVEF in critically ill patients.
Complete list of metadatas

Cited literature [46 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-02465896
Contributor : Myriam Bodescot <>
Submitted on : Tuesday, February 4, 2020 - 11:01:53 AM
Last modification on : Tuesday, November 10, 2020 - 4:50:20 PM
Long-term archiving on: : Tuesday, May 5, 2020 - 2:02:58 PM

File

s13054-019-2582-7.pdf
Publication funded by an institution

Identifiers

Citation

Romain Barthélémy, Xavier Roy, Tujia Javanainen, Alexandre Mebazaa, Benjamin Chousterman. Comparison of echocardiographic indices of right ventricular systolic function and ejection fraction obtained with continuous thermodilution in critically ill patients. Critical Care, BioMed Central, 2019, 23 (1), pp.312. ⟨10.1186/s13054-019-2582-7⟩. ⟨inserm-02465896⟩

Share

Metrics

Record views

288

Files downloads

634