The regulation of AMPK1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways, Cancer Res, vol.67, pp.3043-53, 2007. ,
Regulation of PTEN transcription by p53, Mol Cell, vol.8, pp.317-342, 2001. ,
PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes, Oncogene, vol.18, pp.127-164, 1999. ,
Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability, Oncogene, vol.21, pp.6017-6048, 2002. ,
p53 Target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling, Cell, vol.134, pp.451-60, 2008. ,
Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis, Oncogene, vol.21, pp.1299-303, 2002. ,
The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression, Cancer Res, vol.64, pp.2627-2660, 2004. ,
p53 regulates glucose metabolism through an IKK-NF-?B pathway and inhibits cell transformation, Nat Cell Biol, vol.10, pp.611-619, 2008. ,
TIGAR, a p53-inducible regulator of glycolysis and apoptosis, Cell, vol.126, pp.107-127, 2006. ,
p53 regulates mitochondrial respiration, Science, vol.312, pp.1650-1653, 2006. ,
P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA, Cancer Res, vol.63, pp.3729-3763, 2003. ,
Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma, EMBO J, vol.24, pp.3482-92, 2005. ,
Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53, J Biol Chem, vol.272, pp.22776-80, 1997. ,
GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress, Mol Cell, vol.36, pp.379-92, 2009. ,
ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress, Mol Cell, vol.44, pp.491-501, 2011. ,
p53, a novel regulator of lipid metabolism pathways, J Hepatol, vol.56, pp.656-62, 2012. ,
p53 activation in adipocytes of obese mice, J Biol Chem, vol.278, pp.25395-400, 2003. ,
Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence, Nature, vol.493, pp.689-93, 2013. ,
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function, Proc Natl Acad Sci, vol.107, pp.7455-60, 2010. ,
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species, Proc Natl Acad Sci, vol.107, pp.7461-7467, 2010. ,
Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells, Nature, vol.493, pp.542-548, 2013. ,
Glycolytic enzymes can modulate cellular life span, Cancer Res, vol.65, pp.177-85, 2005. ,
p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase, Nat Cell Biol, vol.13, pp.310-316, 2011. ,
PGC-1alpha, a key modulator of p53, promotes cell survival upon metabolic stress, Mol Cell, vol.44, pp.621-655, 2011. ,
Requirement of the ATM/p53 tumor suppressor pathway for glucose homeostasis, Mol Cell Biol, vol.30, pp.5787-94, 2010. ,
Glucose tolerance in mice is linked to the dose of the p53 transactivation domain, Endocr Res, vol.38, pp.139-50, 2012. ,
Redox regulation of p53, redox effectors regulated by p53: a subtle balance, Antioxid Redox Signal, vol.16, pp.1285-94, 2012. ,
A nucleocytoplasmic malate dehydrogenase regulates p53 transcriptional activity in response to metabolic stress, Cell Death Differ, vol.16, pp.738-786, 2009. ,
Engaging the p53 metabolic brake drives senescence, Cell Res, vol.23, pp.739-779, 2013. ,
The increase of cell-membranous phosphatidylcholines containing polyunsaturated fatty acid residues induces phosphorylation of p53 through activation of ATR, J Cell Sci, vol.120, pp.4134-4177, 2007. ,
Role of p53 in mitochondrial biogenesis and apoptosis in skeletal muscle, Physiol Genomics, vol.37, pp.58-66, 2009. ,
p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity, Cell Death Differ, vol.20, pp.744-83, 2013. ,
p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner. Preiss T, PloS One, vol.3, p.3707, 2008. ,
A crucial role for adipose tissue p53 in the regulation of insulin resistance, Nat Med, vol.15, pp.1082-1089, 2009. ,
Telomere dysfunction induces metabolic and mitochondrial compromise, Nature, vol.470, pp.359-65, 2011. ,
The antioxidant function of the p53 tumor suppressor, Nat Med, vol.11, pp.1306-1319, 2005. ,
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence, Cell, vol.149, pp.1269-83, 2012. ,
La sénescence cellulaire, Med Sci, vol.28, pp.288-96, 2012. ,
Une re-vue de la sénescence cellulaire, Med Sci (Paris), vol.25, pp.153-60, 2009. ,
La réactivation par translecture du gène p53 possédant une mutation non-sens induit l'apoptose de cellules cancéreuses, Med Sci, vol.27, pp.585-591, 2011. ,