Bis(het)aryl-1,2,3-triazole quinuclidines as α7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [18F]-radiolabeling and PET study in rats

Aziz Ouach; Johnny Vercouillie; Emilie Bertrand; Nuno Rodrigues; Frédéric Pin; Sophie Serriere; Liliana Boiaryna; Agnes Chartier; Nathalie Percina; Pakorn Tangpong; Zuhal Gulhan; Céline Mothes; Jean-Bernard Deloye; Denis Guilloteau; Guylène Page; Franck Suzenet; Frederic Buron; Sylvie Chalon; Sylvain Routier

doi:10.1016/j.ejmech.2019.06.049

Journal Articles European Journal of Medicinal Chemistry Year : 2019

Bis(het)aryl-1,2,3-triazole quinuclidines as α7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [18F]-radiolabeling and PET study in rats

(1) , (2) , (3) , (4) , (5) , (6) , (5) , , (1) , , , (7) , (8) , (2) , (9) , (10) , (1) , (2) , (1)

1
2
3
4
5
6
7
8
9
10

Aziz Ouach

Function : Author

Institut de Chimie Organique et Analytique

Johnny Vercouillie

Function : Author
PersonId : 184489
IdHAL : johnny-vercouillie
ORCID : 0000-0002-7474-7778
IdRef : 076157105

Imagerie et cerveau

Emilie Bertrand

Function : Author

Ecole Nationale de la Santé Publique

Nuno Rodrigues

Function : Author

Centro de Estudos Geograficos, IGOT

Frédéric Pin

Function : Author

Unité de Recherche en Chimie Organique et Macromoléculaire

Sophie Serriere

Function : Author

CHRU Tours, Hôpital Bretonneau

Liliana Boiaryna

Function : Author

Unité de Recherche en Chimie Organique et Macromoléculaire

Agnes Chartier

Function : Author
PersonId : 742332
IdHAL : agnes-chartier
ORCID : 0000-0003-4495-7755
IdRef : 032187904

Nathalie Percina

Function : Author

Institut de Chimie Organique et Analytique

Pakorn Tangpong

Function : Author

Zuhal Gulhan

Function : Author

Céline Mothes

Function : Author

Synthèse, Structure et Fonction de Molécules Bioactives

Jean-Bernard Deloye

Function : Author

Cyclopharma

Denis Guilloteau

Function : Author

Imagerie et cerveau

Guylène Page

Function : Author

Unité neurovasculaire et troubles cognitifs

Franck Suzenet

Function : Author
PersonId : 758200
ORCID : 0000-0003-1394-1603
IdRef : 151924996

Institut de Chimie Organique et Analytique

Frederic Buron

Function : Author

Institut de Chimie Organique et Analytique

Sylvie Chalon

Function : Author
PersonId : 180494
IdHAL : sylvie-chalon
ORCID : 0000-0003-1865-8380
IdRef : 076185249

Imagerie et cerveau

Sylvain Routier

Function : Author
PersonId : 936554
ORCID : 0000-0002-2823-0591
IdRef : 118636367

Institut de Chimie Organique et Analytique

Domains

Organic chemistry

Fichier principal

S0223523419305768.pdf (952.71 Ko)

Origin : Files produced by the author(s)

Sylvie Chalon : Connect in order to contact the contributor

https://www.hal.inserm.fr/inserm-02458368

Submitted on : Monday, October 25, 2021-1:29:34 PM

Last modification on : Friday, March 24, 2023-2:53:23 PM

Long-term archiving on: Wednesday, January 26, 2022-8:11:31 PM

Dates and versions

inserm-02458368 , version 1 (25-10-2021)

Licence

Attribution - NonCommercial - CC BY 4.0

Identifiers

HAL Id : inserm-02458368 , version 1
DOI : 10.1016/j.ejmech.2019.06.049
PII : S0223-5234(19)30576-8

Cite

Aziz Ouach, Johnny Vercouillie, Emilie Bertrand, Nuno Rodrigues, Frédéric Pin, et al.. Bis(het)aryl-1,2,3-triazole quinuclidines as α7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [18F]-radiolabeling and PET study in rats. European Journal of Medicinal Chemistry, 2019, 179, pp.449-469. ⟨10.1016/j.ejmech.2019.06.049⟩. ⟨inserm-02458368⟩

Export

BibTeX TEI Dublin Core DC Terms EndNote Datacite

Collections

INSERM CEA UNIV-TOURS CNRS UNIV-ORLEANS UNIV-POITIERS ICOA COMUE-NORMANDIE INC-CNRS CEA-DRF UNIV-RENNES UNILEHAVRE SORBONNE-UNIVERSITE URCOM SU-SCIENCES LABOS-XL-CHEM

88 View

38 Download

Bis(het)aryl-1,2,3-triazole quinuclidines as α7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [18F]-radiolabeling and PET study in rats

Domains

Dates and versions

Licence

Identifiers

Cite

Export

Collections

Altmetric

Share