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Pixantrone: a B-cell-depleting immunosuppressant for multiple sclerosis patients with active disease

Richard Gonsette 1 Marc Debouverie 2 Christian Sindic 1 Jean-Christophe Ferré 3 Gilles Edan 4
4 VisAGeS - Vision, Action et Gestion d'informations en Santé
INSERM - Institut National de la Santé et de la Recherche Médicale : U746, Inria Rennes – Bretagne Atlantique , IRISA-D5 - SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE
Abstract : Mitoxantrone has been approved for patients with worsening relapsing-remitting (RR) or secondary progressive multiple sclerosis (SPMS), but its long-term use is limited by its cardiotoxicity. Pixantrone (PIX) is an analog of mitoxantrone.
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https://www.hal.inserm.fr/inserm-02457664
Contributor : Gilles Edan <>
Submitted on : Tuesday, January 28, 2020 - 11:34:37 AM
Last modification on : Thursday, January 30, 2020 - 1:23:22 AM

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Richard Gonsette, Marc Debouverie, Christian Sindic, Jean-Christophe Ferré, Gilles Edan. Pixantrone: a B-cell-depleting immunosuppressant for multiple sclerosis patients with active disease. Multiple Sclerosis Journal, SAGE Publications, 2016, 22 (6), pp.817-821. ⟨10.1177/1352458515601902⟩. ⟨inserm-02457664⟩

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