Ultra-small superparamagnetic iron oxide enhancement is associated with higher loss of brain tissue structure in clinically isolated syndrome - Archive ouverte HAL Access content directly
Journal Articles Multiple Sclerosis Journal Year : 2016

Ultra-small superparamagnetic iron oxide enhancement is associated with higher loss of brain tissue structure in clinically isolated syndrome

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Adil Maarouf
Isabelle Berry
  • Function : Author
  • PersonId : 935780
Laurent Pierot

Abstract

Macrophages are important components of inflammatory processes in multiple sclerosis, closely linked to axonal loss, and can now be observed in vivo using ultra-small superparamagnetic iron oxide (USPIO). In the present 1-year longitudinal study, we aimed to determine the prevalence and the impact on tissue injury of macrophage infiltration in patients after the first clinical event of multiple sclerosis.
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Dates and versions

inserm-02457660 , version 1 (28-01-2020)

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Adil Maarouf, Jean-Christophe Ferré, W Zaaraoui, Arnaud Le Troter, Elise Bannier, et al.. Ultra-small superparamagnetic iron oxide enhancement is associated with higher loss of brain tissue structure in clinically isolated syndrome. Multiple Sclerosis Journal, 2016, 22 (8), pp.1032-1039. ⟨10.1177/1352458515607649⟩. ⟨inserm-02457660⟩
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