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Ultra-small superparamagnetic iron oxide enhancement is associated with higher loss of brain tissue structure in clinically isolated syndrome

Abstract : Macrophages are important components of inflammatory processes in multiple sclerosis, closely linked to axonal loss, and can now be observed in vivo using ultra-small superparamagnetic iron oxide (USPIO). In the present 1-year longitudinal study, we aimed to determine the prevalence and the impact on tissue injury of macrophage infiltration in patients after the first clinical event of multiple sclerosis.
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https://www.hal.inserm.fr/inserm-02457660
Contributor : Gilles Edan <>
Submitted on : Tuesday, January 28, 2020 - 11:33:16 AM
Last modification on : Thursday, January 30, 2020 - 1:23:21 AM

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Adil Maarouf, Jean-Christophe Ferré, Wafaa Zaaraoui, Arnaud Le Troter, Elise Bannier, et al.. Ultra-small superparamagnetic iron oxide enhancement is associated with higher loss of brain tissue structure in clinically isolated syndrome. Multiple Sclerosis Journal, SAGE Publications, 2016, 22 (8), pp.1032-1039. ⟨10.1177/1352458515607649⟩. ⟨inserm-02457660⟩

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