P. J. Hotez, E. Dumonteil, and L. Woc-colburn, Chagas disease: "the new HIV/AIDS of the Americas, vol.6, p.1498, 2012.

A. Rassi, A. Rassi, M. De-rezende, and J. , American trypanosomiasis (Chagas disease), Infect. Dis. Clin. North Am, vol.26, issue.2, pp.275-291, 2012.

K. M. Bonney and D. M. Engman, Autoimmune pathogenesis of Chagas heart disease: looking back, looking ahead, Am. J. Pathol, vol.185, issue.6, pp.1537-1547, 2015.

R. J. Argüello, M. C. Albareda, and M. G. Alvarez, Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease, PLoS ONE, vol.7, issue.5, p.35966, 2012.

J. C. Villar, J. G. Perez, and O. L. Cortes, Trypanocidal drugs for chronic asymptomatic Trypanosoma cruzi infection, Cochrane Database Syst. Rev, vol.27, issue.5, p.3463, 2014.

Y. Sguassero, C. B. Cuesta, and K. N. Roberts, Course of chronic Trypanosoma cruzi infection after treatment based on parasitological and serological tests: a systematic review of follow-up studies, PLoS ONE, vol.10, issue.10, p.139363, 2015.

C. A. Morillo, J. A. Marin-neto, and A. Avezum, Randomized trial of benznidazole for chronic Chagas' cardiomyopathy, N. Engl. J. Med, vol.373, issue.14, pp.1295-1306, 2015.

O. Rodríguez-morales, V. Monteón-padilla, and S. C. Carrillo-sánchez, Experimental vaccines against Chagas disease: a journey through history, J. Immunol. Res, p.489758, 2015.

M. Arce-fonseca, M. Rios-castro, C. Sdel, C. Martínez-cruz, M. Rodríguez-morales et al., Prophylactic and therapeutic DNA vaccines against Chagas disease, Parasit. Vectors, vol.8, issue.121, p.121, 2015.

S. Gupta and N. J. Garg, A two-component DNA-prime/ protein-boost vaccination strategy for eliciting long-term, protective T cell immunity against Trypanosoma cruzi, PLoS Pathog, vol.11, issue.5, p.1004828, 2015.

I. R. Pereira, G. Vilar-pereira, and V. Marques, A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy, PLoS Pathog, vol.11, issue.1, p.1004594, 2015.

E. Dumonteil, J. Escobedo-ortegon, N. Reyes-rodriguez, A. Arjona-torres, and M. J. Ramirez-sierra, Immunotherapy of Trypanosoma cruzi infection with DNA vaccines in mice, Infect. Immun, vol.72, issue.1, pp.46-53, 2004.

E. Dumonteil, M. E. Bottazzi, and B. Zhan, Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects, Expert Rev. Vaccines, vol.11, issue.9, pp.1043-1055, 2012.

D. F. Hoft, C. S. Eickhoff, O. K. Giddings, J. R. Vasconcelos, and M. M. Rodrigues, Trans-sialidase recombinant protein mixed with CpG motif-containing oligodeoxynucleotide induces protective mucosal and systemic Trypanosoma cruzi immunity involving CD8 + CTL and B cell-mediated crosspriming, J. Immunol, vol.179, issue.10, pp.6889-6900, 2007.

O. K. Giddings, C. S. Eickhoff, N. L. Sullivan, and D. F. Hoft, Intranasal vaccinations with the trans-sialidase Antigen plus CpG Adjuvant induce mucosalimmunity protective against conjunctival Trypanosoma cruzi challenges, Infect. Immun, vol.78, issue.3, pp.1333-1338, 2010.

I. A. Bontempi, M. H. Vicco, and G. Cabrera, Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease, Vaccine, vol.33, issue.10, pp.1274-1283, 2015.

J. Bayry, E. Tartour, and D. F. Tough, Targeting CCR4 as an emerging strategy for cancer therapy and vaccines, Trends Pharmacol. Sci, vol.35, issue.4, pp.163-165, 2014.
URL : https://hal.archives-ouvertes.fr/inserm-02455519

J. M. Warfel, L. I. Zimmerman, and T. J. Merkel, Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model, Proc. Natl Acad. Sci. USA, vol.111, issue.2, pp.787-792, 2014.

N. Cerny, A. S. Alberti, and A. E. Bivona, Coadministration of cruzipain and GM-CSF DNAs, a new immunotherapeutic vaccine against Trypanosoma cruzi infection, Hum. Vaccin. Immunother, 2015.

J. Esparza, A brief history of the global effort to develop a preventive HIV vaccine, Vaccine, vol.31, issue.35, pp.3502-3518, 2013.