Intravenous immunoglobulin protects from experimental allergic bronchopulmonary aspergillosis via a sialylation-dependent mechanism - Inserm - Institut national de la santé et de la recherche médicale Accéder directement au contenu
Article Dans Une Revue European Journal of Immunology Année : 2019

Intravenous immunoglobulin protects from experimental allergic bronchopulmonary aspergillosis via a sialylation-dependent mechanism

Résumé

Intravenous immunoglobuin (IVIG) exerts protective effects in experimental allergic bronchopulmonary aspergillosis (ABPA) via a sialylation-dependent mechanism. The protection was associated with reduced recruitment of eosinophils, diminished goblet cell hyperplasia, suppressed Th2 and Th17 responses and reciprocally enhanced regulatory T cells and IL-10, and decreased IgE levels in the circulation.

Domaines

Immunité innée Allergologie

Jagadeesh Bayry  : Connectez-vous pour contacter le contributeur

https://inserm.hal.science/inserm-02455434

Soumis le : dimanche 26 janvier 2020-10:55:46

Dernière modification le : vendredi 19 avril 2024-16:18:59

Consulter le texte intégral

Dates et versions

inserm-02455434 , version 1 (26-01-2020)

Identifiants

Citer

Silvia Bozza, Fabian Käsermann, Srini V. Kaveri, Luigina Romani, Jagadeesh Bayry. Intravenous immunoglobulin protects from experimental allergic bronchopulmonary aspergillosis via a sialylation-dependent mechanism. European Journal of Immunology, 2019, 49 (1), pp.195-198. ⟨10.1002/eji.201847774⟩. ⟨inserm-02455434⟩

Exporter

BibTeX XML-TEI Dublin Core DC Terms EndNote DataCite

Collections

INSERM UNIV-PARIS7 EPHE CORDELIERS PSL USPC SORBONNE-UNIVERSITE SU-SCIENCES UP-SANTE
28 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More