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Intravenous immunoglobulin protects from experimental allergic bronchopulmonary aspergillosis via a sialylation-dependent mechanism

Abstract : Intravenous immunoglobuin (IVIG) exerts protective effects in experimental allergic bronchopulmonary aspergillosis (ABPA) via a sialylation-dependent mechanism. The protection was associated with reduced recruitment of eosinophils, diminished goblet cell hyperplasia, suppressed Th2 and Th17 responses and reciprocally enhanced regulatory T cells and IL-10, and decreased IgE levels in the circulation.
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https://www.hal.inserm.fr/inserm-02455434
Contributor : Jagadeesh Bayry <>
Submitted on : Sunday, January 26, 2020 - 10:55:46 AM
Last modification on : Friday, September 18, 2020 - 2:35:04 PM

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Silvia Bozza, Fabian Käsermann, Srini Kaveri, Luigina Romani, Jagadeesh Bayry. Intravenous immunoglobulin protects from experimental allergic bronchopulmonary aspergillosis via a sialylation-dependent mechanism. European Journal of Immunology, Wiley-VCH Verlag, 2019, 49 (1), pp.195-198. ⟨10.1002/eji.201847774⟩. ⟨inserm-02455434⟩

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