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Regulatory T Cells under the Mercy of Mitochondria

Abstract : Mitochondria, the powerhouse of the cell, known for producing energy through oxidative phosphorylation and the Krebs cycle, continue gaining notoriety for roles beyond bioenergetics. Recently in Nature, Weinberg et al. (2019) reported that mitochondrial complex III is indispensable for suppressive function of regulatory T cells, thus highlighting the importance of mitochondria in immune tolerance.
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https://www.hal.inserm.fr/inserm-02455433
Contributor : Jagadeesh Bayry <>
Submitted on : Sunday, January 26, 2020 - 10:53:25 AM
Last modification on : Tuesday, July 21, 2020 - 3:53:34 AM

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Mrinmoy Das, Fawaz Alzaid, Jagadeesh Bayry. Regulatory T Cells under the Mercy of Mitochondria. Cell Metabolism, Elsevier, 2019, 29 (2), pp.243-245. ⟨10.1016/j.cmet.2019.01.012⟩. ⟨inserm-02455433⟩

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