Service interruption on Monday 11 July from 12:30 to 13:00: all the sites of the CCSD (HAL, Epiciences, SciencesConf, AureHAL) will be inaccessible (network hardware connection).
Skip to Main content Skip to Navigation
Journal articles

C3 glomerulonephritis in a patient treated with anti–PD-1 antibody

Abstract : Immune checkpoint inhibitors (ICIs) have dramati-cally transformed the treatment of solid tumors. ICIsinduce an immune response against tumoral cells as aresult of the removal of T-cell inhibition [1]. The logicalcounterpart of turning off T-cell inhibitory mechanismsis the onset of immune-related adverse events (irAEs)that affect different organs. Although the most frequentrenal irAE is acute interstitial nephritis [2], we report afirst case of C3 glomerulonephritis (GN) associated withthe use of an antieProgrammed Cell Death 1 (PD-1)humanised antibody.
Document type :
Journal articles
Complete list of metadata
Contributor : Sylvie Le Bihan Connect in order to contact the contributor
Submitted on : Wednesday, January 22, 2020 - 4:03:35 PM
Last modification on : Wednesday, April 27, 2022 - 3:42:52 AM



Simon Ville, Christine Kandel-Aznar, Veronique Fremeaux-Bacchi, Fadi Fakhouri. C3 glomerulonephritis in a patient treated with anti–PD-1 antibody. European Journal of Cancer, Elsevier, 2020, 125, pp.46-48. ⟨10.1016/j.ejca.2019.11.011⟩. ⟨inserm-02449014⟩



Record views