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Kinesin-1 Is a New Actor Involved in Platelet Secretion and Thrombus Stability

Frédéric Adam 1, 2 Alexandre Kauskot 2 Mathieu Kurowska 3 Nicolas Goudin 4 Isabelle Munoz 3 Jean-Claude Bordet 5 Jian-Dong Huang 3 Marijke Bryckaert 2 Alain Fischer 6, 7 Delphine Borgel 8, 2 Geneviève de Saint Basile 3 Olivier D. Christophe 2 Gaël Ménasché 3 
1 UCC - University College Cork
2 HITH - U1176 Inserm - CHU Bicêtre - Hémostase, Inflammation, Thrombose
3 IMAGINE - U1163 - Imagine - Institut des maladies génétiques
4 CHU Necker - Enfants Malades [AP-HP]
5 EA 4609 - Hémostase, Inflammation et sepsis
6 Developpement Normal et Pathologique du Système Immunitaire
7 Chaire Médecine expérimentale (A. Fischer)
8 Department of Hematology [Paris]
Abstract : Platelet secretion is crucial for many physiological platelet responses. Even though several regulators of the fusion machinery for secretory granule exocytosis have been identified in platelets, the underlying mechanisms are not yet fully characterized.
Keywords : blood platelets hemostasis kinesin platelet secretion
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Journal articles
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https://www.hal.inserm.fr/inserm-02440288
Contributor : Gaël Ménasché Connect in order to contact the contributor
Submitted on : Friday, January 31, 2020 - 10:02:47 AM
Last modification on : Saturday, June 25, 2022 - 10:43:56 PM

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INSERM | UNIV-PARIS5 | CNRS | CDF | UNIV-LYON1 | PSL | USPC | UNIV-PARIS-SACLAY | UDL | UNIV-PARIS | UP-SANTE | GS-HEALTH-DRUG-SCIENCES

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Frédéric Adam, Alexandre Kauskot, Mathieu Kurowska, Nicolas Goudin, Isabelle Munoz, et al.. Kinesin-1 Is a New Actor Involved in Platelet Secretion and Thrombus Stability. Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2018, 38 (5), pp.1037-1051. ⟨10.1161/ATVBAHA.117.310373⟩. ⟨inserm-02440288⟩

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