C. L. Bowlus, J. Ahn, T. Chu, and J. R. Gruen, Cloning of a novel MHC-encoded serine peptidase highly expressed by cortical epithelial cells of the thymus, Cell. Immunol, vol.196, pp.80-86, 1999.

A. R. Burton, E. Vincent, P. Y. Arnold, G. P. Lennon, M. Smeltzer et al., On the pathogenicity of autoantigen-specific T-cell receptors, Diabetes, vol.57, pp.1321-1330, 2008.

A. Carrier, C. Nguyen, G. Victorero, S. Granjeaud, D. Rocha et al., Differential gene expression in CD3epsilon-and RAG1-deficient thymuses: definition of a set of genes potentially involved in thymocyte maturation, Immunogenetics, vol.50, pp.255-270, 1999.

S. Cheunsuk, T. Hsu, M. E. Gershwin, and C. L. Bowlus, Analysis of the IDDM candidate gene Prss16 in NOD and NON mice, Dev. Immunol, vol.9, pp.183-186, 2002.

S. Cheunsuk, Z. X. Lian, G. X. Yang, M. E. Gershwin, J. R. Gruen et al., Prss16 is not required for T-cell development, Mol. Cell. Biol, vol.25, pp.789-796, 2005.

P. J. Ebert, S. Jiang, J. Xie, Q. J. Li, and M. M. Davis, An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a, Nat. Immunol, vol.10, pp.1162-1169, 2009.

K. P. Goldman, C. S. Park, M. Kim, P. Matzinger, and C. C. Anderson, Thymic cortical epithelium induces self tolerance, Eur. J. Immunol, vol.35, pp.709-717, 2005.

J. Gommeaux, C. Grégoire, P. Nguessan, M. Richelme, M. Malissen et al., Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes, Eur. J. Immunol, vol.39, pp.956-964, 2009.
URL : https://hal.archives-ouvertes.fr/hal-00408418

C. S. Hsieh, P. Deroos, K. Honey, C. Beers, and A. Y. Rudensky, A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation, J. Immunol, vol.168, pp.2618-2625, 2002.

L. C. Hsing and A. Y. Rudensky, The lysosomal cysteine proteases in MHC class II antigen presentation, Immunol. Rev, vol.207, pp.229-241, 2005.

L. Klein, M. Hinterberger, G. Wirnsberger, and B. Kyewski, Antigen presentation in the thymus for positive selection and central tolerance induction, Nat. Rev. Immunol, vol.9, pp.833-844, 2009.

B. A. Lie, J. A. Todd, F. Pociot, J. Nerup, H. E. Akselsen et al., The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene, Am. J. Hum. Genet, vol.64, pp.793-800, 1999.

A. Lim, V. Baron, L. Ferradini, M. Bonneville, P. Kourilsky et al., Combination of MHC-peptide multimer-based T cell sorting with the Immunoscope permits sensitive ex vivo quantitation and follow-up of human CD8+ T cell immune responses, J. Immunol. Methods, vol.261, pp.177-194, 2002.

W. L. Lo, N. J. Felix, J. J. Walters, H. Rohrs, M. L. Gross et al., An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells, Nat. Immunol, vol.10, pp.1155-1161, 2009.

B. Manoury, E. W. Hewitt, N. Morrice, P. M. Dando, A. J. Barrett et al., An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation, Nature, vol.396, pp.695-699, 1998.

B. Manoury, D. Mazzeo, L. Fugger, N. Viner, M. Ponsford et al., Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP, Nat. Immunol, vol.3, pp.169-174, 2002.

P. Marrack and J. Kappler, Positive selection of thymocytes bearing alpha beta T cell receptors, Curr. Opin. Immunol, vol.9, pp.80144-80150, 1997.

T. M. Mccaughtry, T. A. Baldwin, M. S. Wilken, and K. A. Hogquist, Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla, J. Exp. Med, vol.205, pp.2575-2584, 2008.

J. A. Musson, N. Walker, H. Flick-smith, E. D. Williamson, and J. H. Robinson, Differential processing of CD4 T-cell epitopes from the protective antigen of Bacillus anthracis, J. Biol. Chem, vol.278, pp.52425-52431, 2003.

J. A. Musson, M. Morton, N. Walker, H. M. Harper, H. V. Mcneill et al., Sequential proteolytic processing of the capsular Caf1 antigen of Yersinia pestis for major histocompatibility complex class II-restricted presentation to T lymphocytes, J. Biol. Chem, vol.281, pp.26129-26135, 2006.

T. Y. Nakagawa, W. H. Brissette, P. D. Lira, R. J. Griffiths, N. Petrushova et al., Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice, Immunity, vol.10, pp.207-217, 1999.

C. Pannetier, M. Cochet, S. Darche, A. Casrouge, M. Zöller et al., The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments, Proc. Natl. Acad. Sci. USA, vol.90, pp.4319-4323, 1993.

E. B. Plüger, M. Boes, C. Alfonso, C. J. Schröter, H. Kalbacher et al., Specific role for cathepsin S in the generation of antigenic peptides in vivo, Eur. J. Immunol, vol.32, pp.467-476, 2002.

G. P. Shi, J. A. Villadangos, G. Dranoff, C. Small, L. Gu et al., Cathepsin S required for normal MHC class II peptide loading and germinal center development, Immunity, vol.10, pp.197-206, 1999.