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Prospective assessment of the predictive value of the BRCA1 gene status in sarcoma patients treated with trabectedin: an updated analysis of the EORTC 62091 trial

Abstract : We describe the predictive value of BRCA1 gene status on trabectedin efficacy and found no correlation despite the mechanisms of action of this drug that rely on DNA repair systems.
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https://hal.umontpellier.fr/hal-02289349
Contributor : Anthony Herrada <>
Submitted on : Monday, September 16, 2019 - 3:37:40 PM
Last modification on : Wednesday, November 25, 2020 - 11:30:08 AM

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Antoine Italiano, Nathan Touati, Saskia Litière, Françoise Collin, Philippe Pourquier, et al.. Prospective assessment of the predictive value of the BRCA1 gene status in sarcoma patients treated with trabectedin: an updated analysis of the EORTC 62091 trial. Cancer Medicine, Wiley, 2018, 7 (5), pp.1575-1577. ⟨10.1002/cam4.1403⟩. ⟨hal-02289349⟩

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