Calcium influx through calcium leak channels is responsible for the elevated levels of calcium-dependent proteolysis in dystrophic myotubes, J. Biol. Chem, vol.275, pp.9452-9460, 2000. ,
Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IkappaB alpha/NF-kappaB pathway in limbgirdle muscular dystrophy type 2A, Nat. Med, vol.5, pp.503-511, 1999. ,
Three fast myosin heavy chains in adult rat skeletal muscle, FEBS Lett, vol.235, pp.153-155, 1988. ,
ATPase activity of myosin correlated with speed of muscle shortening, J. Gen. Physiol, vol.50, pp.197-218, 1967. ,
Calpains in muscle wasting, Int. J. Biochem. Cell Biol, vol.37, pp.2115-2133, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-01610051
Molecular, cellular, and muscle strip mechanics of the mdx mouse diaphragm, Am. J. Physiol. Cell Physiol, vol.304, 2013. ,
Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle, Nat. Med, vol.15, pp.325-330, 2009. ,
Lateral force transmission across costameres in skeletal muscle, Exerc. Sport Sci. Rev, vol.31, pp.73-78, 2003. ,
Costameres mediate force transduction in healthy skeletal muscle and are altered in muscular dystrophies, J. Muscle Res. Cell Motil, vol.25, pp.590-592, 2004. ,
Maximum shortening velocity and coexistence of myosin heavy chain isoforms in single skinned fast fibres of rat skeletal muscle, J. Muscle Res. Cell Motil, vol.15, pp.413-419, 1994. ,
Myofibrillar ATPase activity during isometric contraction and isomyosin composition in rat single skinned muscle fibres, J. Physiol, vol.481, pp.663-675, 1994. ,
The sites and topology of mitochondrial superoxide production, Exp. Gerontol, vol.45, pp.466-472, 2010. ,
Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy, Cell, vol.82, pp.90471-90480, 1995. ,
Actin sliding velocity on pure myosin isoforms from dystrophic mouse muscles, Muscle Nerve, vol.40, pp.249-256, 2009. ,
Effect of inorganic phosphate on the force and number of myosin cross-bridges during the isometric contraction of permeabilized muscle fibers from rabbit psoas, Biophys. J, vol.95, pp.5798-5808, 2008. ,
Parallel protein and transcript profiles of FSHD patient muscles correlate to the D4Z4 arrangement and reveal a common impairment of slow to fast fibre differentiation and a general deregulation of MyoD-dependent genes, Proteomics, vol.6, pp.5303-5321, 2006. ,
Nebulin alters cross-bridge cycling kinetics and increases thin filament activation: a novel mechanism for increasing tension and reducing tension cost, J. Biol. Chem, vol.284, pp.30889-30896, 2009. ,
Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5, Gene, vol.269, pp.131-140, 2001. ,
Identification of putative in vivo substrates of calpain 3 by comparative proteomics of overexpressing transgenic and nontransgenic mice, Proteomics, vol.6, pp.6075-6084, 2006. ,
Molecular basis of muscular dystrophies, Muscle Nerve, vol.23, pp.1456-1471, 2000. ,
Oxidative stress of myosin contributes to skeletal muscle dysfunction in rats with chronic heart failure, Am. J. Physiol. Heart Circ. Physiol, vol.292, 2007. ,
Myosin molecular motor dysfunction in dystrophic mouse diaphragm, Am. J. Physiol, vol.277, pp.1170-1176, 1999. ,
Velocity of actomyosin sliding in vitro is reduced in dystrophic mouse diaphragm, Am. J. Respir. Crit. Care Med, vol.165, pp.250-253, 2002. ,
Structural and functional alterations of muscle fibres in the novel mouse model of facioscapulohumeral muscular dystrophy, J. Physiol, vol.584, pp.997-1009, 2007. ,
Reversal of the cross-bridge force-generating transition by photogeneration of phosphate in rabbit psoas muscle fibres, J. Physiol, vol.451, pp.247-278, 1992. ,
Proteomics identification of differentially expressed proteins in the muscle of dysferlin myopathy patients, Proteomics Clin. Appl, vol.3, pp.486-497, 2009. ,
Evidence of oxidative stress in mdx mouse muscle: studies of the prenecrotic state, J. Neurol. Sci, vol.161, pp.77-84, 1998. ,
Methionine oxidation activates a transcription factor in response to oxidative stress, Proc. Natl. Acad. Sci. U.S.A, vol.110, pp.9493-9498, 2013. ,
Free radicals in the physiological control of cell function, Physiol. Rev, vol.82, pp.47-95, 2002. ,
Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions, J. Clin. Invest, vol.113, pp.115-123, 2004. ,
The relation of muscle biochemistry to muscle physiology, Annu. Rev. Physiol, vol.42, pp.293-309, 1980. ,
Cross-bridge model of muscle contraction. Quantitative analysis, Biophys. J, vol.29, pp.85126-85131, 1980. ,
Costameres: the Achilles' heel of Herculean muscle, J. Biol. Chem, vol.278, pp.13591-13594, 2003. ,
Membrane organization of the dystrophin-glycoprotein complex, Neuropathol. Appl. Neurobiol, vol.66, pp.461-470, 1991. ,
The muscular dystrophies, Semin. Neurol, vol.32, pp.255-263, 2012. ,
Tropomodulin is associated with the free (pointed) ends of the thin filaments in rat skeletal muscle, J. Cell Biol, vol.120, pp.411-420, 1993. ,
Structural basis for the regulation of muscle contraction by troponin and tropomyosin, J. Mol. Biol, vol.379, pp.929-935, 2008. ,
Qualitatively different cross-bridge attachments in fast and slow muscle fiber types, Biochem. Biophys. Res. Commun, vol.385, pp.44-48, 2009. ,
Molecular mechanism of actomyosin-based motility, Cell. Mol. Life Sci, vol.62, pp.1462-1477, 2005. ,
Oxidoreduction of protein thiols in redox regulation, Biochem. Soc. Trans, vol.33, pp.1378-1381, 2005. ,
Atrophy, fibrosis, and increased PAX7-positive cells in pharyngeal muscles of oculopharyngeal muscular dystrophy patients, J. Neuropathol. Exp. Neurol, vol.72, pp.234-243, 2013. ,
, , 2014.
, Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle, Mol. Biol. Cell, vol.25, pp.852-865
The calpain system, Physiol. Rev, vol.83, pp.731-801, 2003. ,
Regulation of contraction in striated muscle, Physiol. Rev, vol.80, pp.853-924, 2000. ,
Accessibility of myofilament cysteines and effects on ATPase depend on the activation state during exposure to oxidants, PLoS ONE, vol.8, p.69110, 2013. ,
Role of oxidative stress in cardiac dysfunction of PPARalpha-/-mice, Am. J. Physiol. Heart Circ. Physiol, vol.293, pp.93-102, 2007. ,
Oxidation and S-nitrosylation of cysteines in human cytosolic and mitochondrial glutaredoxins: effects on structure and activity, J. Biol. Chem, vol.282, pp.14428-14436, 2007. ,
Differential susceptibility of human skeletal muscle proteins to free radical induced oxidative damage: a histochemical, immunocytochemical and electron microscopical study in vitro, Acta Neuropathol, vol.92, pp.331-340, 1996. ,
SelR reverses Mical-mediated oxidation of actin to regulate F-actin dynamics, Nat. Cell Biol, vol.15, pp.1445-1454, 2013. ,
Muscle structure and theories of contraction, Prog. Biophys. Biophys. Chem, vol.7, pp.255-318, 1957. ,
Proposed mechanism of force generation in striated muscle, Nature, vol.233, pp.533-538, 1971. ,
Time-resolved X-ray diffraction studies of the myosin layer-line reflections during muscle contraction, J. Mol. Biol, vol.158, issue.82, pp.90253-90257, 1982. ,
Redox regulation of skeletal muscle, IUBMB Life, vol.60, pp.497-501, 2008. ,
Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic, Biol. Med, vol.45, pp.1-17, 2008. ,
Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle, FASEB J, vol.18, pp.1499-1506, 2004. ,
Oxidized proteins: intracellular distribution and recognition by the proteasome, Arch. Biochem. Biophys, vol.462, pp.231-237, 2007. ,
Congenital fiber type disproportion myopathy caused by LMNA mutations, J. Neurol. Sci, vol.340, pp.94-98, 2014. ,
The 2013 version of the gene table of monogenic neuromuscular disorders (nuclear genome), Neuromuscul. Disord, vol.22, pp.1108-1135, 2012. ,
Structural changes during activation of frog muscle studied by time-resolved X-ray diffraction, J. Mol. Biol, vol.188, pp.325-342, 1986. ,
Exacerbation of pathology by oxidative stress in respiratory and locomotor muscles with Duchenne muscular dystrophy, J. Physiol, vol.589, pp.2161-2170, 2011. ,
MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation, Mol. Cell, vol.51, pp.397-404, 2013. ,
The essential requirement for superoxide radical and nitric oxide formation for normal physiological function and healthy aging, Mitochondrion, vol.7, pp.1-5, 2007. ,
Studies of the diffuse x-ray scattering from contracting frog skeletal muscles, Biophys. J, vol.57, pp.82617-82622, 1990. ,
Mechanism of adenosine triphosphate hydrolysis by actomyosin, Biochemistry, vol.10, pp.4617-4624, 1971. ,
Increased myofibrillar protein catabolism in Duchenne muscular dystrophy measured by 3-methylhistidine excretion in the urine, J. Neurol. Neurosurg. Psychiatry, vol.40, pp.979-981, 1977. ,
Single-molecule biomechanics with optical methods, Science, vol.283, pp.1689-1695, 1999. ,
Oxidative stress by monoamine oxidases is causally involved in myofiber damage in muscular dystrophy, Hum. Mol. Genet, vol.19, pp.4207-4215, 2010. ,
Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo, Mol. Cell, vol.9, pp.387-399, 2002. ,
Muscular dystrophies, Lancet, vol.381, pp.845-860, 2013. ,
Dystrophin-glycoprotein complex: post-translational processing and dystroglycan function, J. Biol. Chem, vol.278, pp.15457-15460, 2003. ,
S-glutathionylation of troponin I (fast) increases contractile apparatus Ca2+ sensitivity in fast-twitch muscle fibres of rats and humans, J. Physiol, vol.590, pp.1443-1463, 2012. ,
Movement and force produced by a single myosin head, Nature, vol.378, pp.209-212, 1995. ,
Oxidative stress, chronic disease, and muscle wasting, Muscle Nerve, vol.35, pp.411-429, 2007. ,
How mitochondria produce reactive oxygen species, Biochem. J, vol.417, pp.1-13, 2009. ,
Calpain-3 is autolyzed and hence activated in human skeletal muscle 24 h following a single bout of eccentric exercise, J. Appl. Physiol, vol.103, pp.926-931, 1985. ,
Endogenous calpain-3 activation is primarily governed by small increases in resting cytoplasmic [Ca2+] and is not dependent on stretch, J. Biol. Chem, vol.284, pp.7811-7819, 2009. ,
Ca2+ activation of diffusible and bound pools of mu-calpain in rat skeletal muscle, J. Physiol, vol.576, pp.595-612, 2006. ,
Oxidative stress and muscle homeostasis, Curr. Opin. Clin. Nutr. Metab. Care, vol.13, pp.236-242, 2010. ,
Myosin is reversibly inhibited by S-nitrosylation, Biochem. J, vol.424, pp.221-231, 2009. ,
Pointed-end capping by tropomodulin modulates actomyosin crossbridge formation in skeletal muscle fibers, FASEB J, vol.28, pp.408-415, 2014. ,
A vinculin-containing cortical lattice in skeletal muscle: transverse lattice elements ("costameres") mark sites of attachment between myofibrils and sarcolemma, Proc. Natl. Acad. Sci. U.S.A, vol.80, pp.1008-1012, 1983. ,
A model of crossbridge action: the effects of ATP, ADP and Pi. J. Muscle Res. Cell Motil, vol.10, pp.181-196, 1989. ,
Early decrease of IIx myosin heavy chain transcripts in Duchenne muscular dystrophy, Biochem. Biophys. Res. Commun, vol.255, pp.466-469, 1999. ,
Adaptations in myosin heavy chain expression and contractile function in dystrophic mouse diaphragm, Am. J. Physiol, vol.265, pp.834-841, 1993. ,
Protein maintenance in aging and replicative senescence: a role for the peptide methionine sulfoxide reductases, Biochim. Biophys. Acta, vol.1703, pp.261-266, 2005. ,
Cellular and molecular diversities of mammalian skeletal muscle fibers, Rev. Physiol. Biochem. Pharmacol, vol.116, pp.1-76, 1990. ,
Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production, Physiol. Rev, vol.88, pp.1243-1276, 2008. ,
Reactive oxygen species: impact on skeletal muscle, Compr. Physiol, vol.1, pp.941-969, 2011. ,
Mechanisms of disuse muscle atrophy: role of oxidative stress, Am. J. Physiol. Regul. Integr. Comp. Physiol, vol.288, pp.337-344, 2005. ,
Oxidative stress as a potential pathogenic mechanism in an animal model of Duchenne muscular dystrophy, Neuromuscul. Disord, vol.7, pp.379-386, 1997. ,
Lateral transmission of force is impaired in skeletal muscles of dystrophic mice and very old rats, J. Physiol, vol.589, pp.1195-1208, 2011. ,
Muscle cells from mdx mice have an increased susceptibility to oxidative stress, Neuromuscul. Disord, vol.8, pp.14-21, 1998. ,
Sarcomere-length dependence of myosin filament structure in skeletal muscle fibres of the frog, J. Physiol, vol.592, pp.1119-1137, 2014. ,
Motion of myosin head domains during activation and force development in skeletal muscle, Proc. Natl. Acad. Sci. U.S.A, vol.108, 2011. ,
The myosin motor in muscle generates a smaller and slower working stroke at higher load, Nature, vol.428, pp.578-581, 2004. ,
Cell signaling. H2O2, a necessary evil for cell signaling, Science, vol.312, pp.1882-1883, 2006. ,
The dystrophin complex forms a mechanically strong link between the sarcolemma and costameric actin, J. Cell Biol, vol.150, pp.1209-1214, 2000. ,
Fibre types in extraocular muscles: a new myosin isoform in the fast fibres, J. Muscle Res. Cell Motil, vol.8, pp.161-172, 1987. ,
Predominant fiber atrophy and fiber type disproportion in early ullrich disease, Muscle Nerve, vol.38, pp.1184-1191, 2008. ,
Three myosin heavy chain isoforms in type 2 skeletal muscle fibres, J. Muscle Res. Cell Motil, vol.10, pp.197-205, 1989. ,
Molecular diversity of myofibrillar proteins: gene regulation and functional significance, Physiol. Rev, vol.76, pp.371-423, 1996. ,
The role of immunocytochemistry in congenital myopathies, Neuromuscul. Disord, vol.8, 1998. ,
Redox modulation of contractile function in respiratory and limb skeletal muscle, Respir. Physiol. Neurobiol, vol.151, pp.229-241, 2006. ,
Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence, J. Biol. Chem, vol.270, pp.31158-31162, 1995. ,
Calpains are activated in necrotic fibers from mdx dystrophic mice, J. Biol. Chem, vol.270, pp.10909-10914, 1995. ,
Cyclic oxidation and reduction of protein methionine residues is an important antioxidant mechanism, Mol. Cell Biochem. 234, vol.235, pp.3-9, 2002. ,
The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy, Nature, vol.352, pp.536-539, 1991. ,
Repriming the actomyosin crossbridge cycle, Proc. Natl. Acad. Sci. U.S.A, vol.101, pp.12904-12909, 2004. ,
Myofibrillar ATPase activity in skinned human skeletal muscle fibres: fibre type and temperature dependence, J. Physiol, vol.493, pp.299-307, 1996. ,
Hydrogen peroxide: a signaling messenger, Antioxid. Redox Signal, vol.8, pp.243-270, 2006. ,
Lateral transmission of tension in frog myofibers: a myofibrillar network and transverse cytoskeletal connections are possible transmitters, J. Cell. Physiol, vol.114, pp.346-364, 1983. ,
Calpains and muscular dystrophies, Int. J. Biochem. Cell Biol, vol.32, pp.1-5, 2000. ,
The role of free radicals in the pathophysiology of muscular dystrophy, J. Appl. Physiol, vol.102, pp.1677-1686, 1985. ,
Oxidized mitochondrial protein degradation and repair in aging and oxidative stress, Antioxid. Redox Signal, vol.13, pp.539-549, 2010. ,
The stiffness of rabbit skeletal actomyosin cross-bridges determined with an optical tweezers transducer, Biophys. J, vol.75, issue.98, pp.74061-74066, 1998. ,
Increased rates of myofibrillar protein breakdown in muscle-wasting diseases, Muscle Nerve, vol.4, pp.62-66, 1981. ,
Tropomodulin caps the pointed ends of actin filaments, J. Cell Biol, vol.127, pp.1627-1635, 1994. ,
Fast muscle fibers are preferentially affected in Duchenne muscular dystrophy, Cell, vol.52, pp.503-513, 1988. ,
Co-expression of multiple myosin heavy chain genes, in addition to a tissue-specific one, in extraocular musculature, J. Cell Biol, vol.101, pp.618-629, 1985. ,
Nitric oxide (NO) protects against cellular damage by reactive oxygen species, Toxicol. Lett, pp.221-226, 1995. ,
Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme, EMBO J, vol.11, pp.3323-3335, 1992. ,
An x-ray diffraction study on early structural changes in skeletal muscle contraction, Biophys. J, vol.84, p.74925, 2003. ,
Role of the calcium-calpain pathway in cytoskeletal damage after eccentric contractions, J. Appl. Physiol, vol.105, pp.352-357, 1985. ,
, Conflict of Interest Statement: The authors declare that the research was con