P. R. Dodge and M. N. Swartz, Bacterial meningitis-a review of selected aspects. II. Special neurologic problems, postmeningitic complications and clinicopathological correlations, N Engl J Med, vol.272, pp.954-960, 1965.

D. Van-de-beek, J. De-gans, A. R. Tunkel, and E. F. Wijdicks, Community-acquired bacterial meningitis in adults, N Engl J Med, vol.354, pp.44-53, 2006.

S. I. Aronin, P. Peduzzi, and V. J. Quagliarello, Community-acquired bacterial meningitis: risk stratification for adverse clinical outcome and effect of antibiotic timing, Ann Intern Med, vol.129, pp.862-869, 1998.

M. C. Brouwer, A. R. Tunkel, and D. Van-de-beek, Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis, Clin Microbiol Rev, vol.23, pp.467-492, 2010.

N. G. Martin, M. A. Iro, M. Sadarangani, R. Goldacre, A. J. Pollard et al., Hospital admissions for viral meningitis in children in England over five decades: a population-based observational study, Lancet Infect Dis, vol.16, issue.16, pp.30201-30209, 2016.

. Socié-té-française-de-microbiologie,

, Diagnostic microbiologique des infections du système nerveux central [Microbiological diagnostic of central nervous system infections

, Référentiel en microbiologie mé dicale (REMIC): Socié té Française de Microbiologie Ed, pp.155-164, 2015.

D. Chang, J. F. Okulicz, L. E. Nielsen, and B. K. White, A tertiary care center's experience with novel molecular meningitis/encephalitis diagnostics and implementation with antimicrobial stewardship, Mil Med, vol.183, pp.24-27, 2018.

G. K. Bårnes, E. K. Gudina, M. Berhane, A. Abdissa, G. Tesfaw et al., New molecular tools for meningitis diagnostics in Ethiopia-a necessary step towards improving antimicrobial prescription, BMC Infect Dis, vol.18, p.684, 2018.

A. L. Leber, K. Everhart, J. M. Balada-llasat, J. Cullison, J. Daly et al., Multicenter evaluation of Bio-Fire FilmArray Meningitis/Encephalitis panel for detection of bacteria, viruses, and yeast in cerebrospinal fluid specimens, J Clin Microbiol, vol.54, pp.2251-2261, 2016.

D. Bard, J. Alby, and K. , Point-counterpoint: meningitis/encephalitis syndromic testing in the clinical laboratory, J Clin Microbiol, vol.56, 2018.

S. F. Lumley, D. Pritchard, A. Dutta, P. C. Matthews, and K. Cann, Multiplex PCR reveals high prevalence of enterovirus and HHV6 in acellular paediatric cerebrospinal fluid samples, J Infect, vol.77, issue.3, pp.249-257, 2018.

S. H. Lee, S. Y. Chen, J. Y. Chien, T. F. Lee, J. M. Chen et al., Usefulness of the FilmArray meningitis/ encephalitis (M/E) panel for the diagnosis of infectious meningitis and encephalitis in Taiwan, J Microbiol Immunol Infect, 2019.

R. M. Liesman, A. P. Strasburg, A. K. Heitman, E. S. Theel, R. Patel et al., Evaluation of a commercial multiplex molecular panel for diagnosis of infectious meningitis and encephalitis, J Clin Microbiol, vol.26, 2018.

S. H. Wootton, E. Aguilera, L. Salazar, A. C. Hemmert, and R. Hasbun, Enhancing pathogen identification in patients with meningitis and a negative Gram stain using the BioFire FilmArray( ® ) Meningitis/Encephalitis panel, Ann Clin Microbiol Antimicrob, vol.15, p.26, 2016.

A. Eichinger, A. Hagen, M. Meyer-bü-hn, and J. Huebner, Clinical benefits of introducing real-time multiplex PCR for cerebrospinal fluid as routine diagnostic at a tertiary care pediatric center, Infection, vol.47, issue.1, p.30187216, 2019.

A. J. Blaschke, K. M. Holmberg, J. A. Daly, A. L. Leber, D. Bard et al., Retrospective evaluation of infants aged 1 to 60 days with residual cerebrospinal fluid (CSF) tested using the FilmArray Routine use evaluation of FilmArray Meningitis/Encephalitis panel, PLOS ONE, 2019.

, Meningitis/Encephalitis (ME) panel, J Clin Microbiol, vol.56, 2018.

H. S. Arora, B. I. Asmar, H. Salimnia, P. Agarwal, S. Chawla et al., Enhanced identification of group B Streptococcus and Escherichia coli in young infants with meningitis using the Biofire Filmarray Meningitis/Encephalitis panel, Pediatr Infect Dis J, vol.36, pp.685-687, 2017.

E. H. Graf and M. V. Farquharson, Cá rdenas AM. Comparative evaluation of the FilmArray meningitis/encephalitis molecular panel in a pediatric population, Diagn Microbiol Infect Dis, vol.87, pp.92-94, 2017.

K. Messacar, G. Breazeale, C. C. Robinson, and S. R. Dominguez, Potential clinical impact of the film array meningitis encephalitis panel in children with suspected central nervous system infections, Diagn Microbiol Infect Dis, vol.86, pp.118-120, 2016.

J. Rhein, N. C. Bahr, A. C. Hemmert, J. L. Cloud, S. Bellamkonda et al., Diagnostic performance of a multiplex PCR assay for meningitis in an HIV-infected population in Uganda, Diagn Microbiol Infect Dis, vol.84, pp.268-273, 2016.

R. J. Richards, M. S. Simon, C. D. Phillips, L. Lief, S. G. Jenkins et al., Rapid detection of Listeria monocytogenes rhombencephalitis in an immunocompetent patient by multiplexed PCR, BMJ Case Rep, vol.8, 2018.

S. Kenneth, A. S. Bangdiwala, R. Kwizera, T. K. Kandole, L. Tugume et al., Symptomatic cryptococcal antigenemia presenting as early cryptococcal meningitis with negative CSF analysis, Clin Infect Dis. Forthcoming, 2018.

D. A. Green, M. Pereira, B. Miko, S. Radmard, S. Whittier et al., Clinical significance of Human Herpesvirus 6 positivity on the FilmArray Meningitis/Encephalitis panel, Clin Infect Dis, vol.67, pp.1125-1128, 2018.

C. Launes, D. Casas-alba, C. Fortuny, A. Valero-rello, M. Cabrerizo et al., Utility of FilmArray Meningitis/Encephalitis panel during outbreak of brainstem encephalitis caused by enterovirus in Catalonia in 2016, J Clin Microbiol, vol.55, pp.336-338, 2016.

S. N. Naccache, M. Lustestica, M. Fahit, J. Mestas, D. Bard et al., One year in the life of a rapid syndromic panel for meningitis/encephalitis: a pediatric tertiary care facility's experience, J Clin Microbiol, vol.56, p.29540454, 2018.

S. Radmard, S. Reid, P. Ciryam, A. Boubour, N. Ho et al., Clinical utilization of the FilmArray Meningitis/Encephalitis (ME) multiplex Polymerase Chain Reaction (PCR) assay, Front Neurol, vol.10, p.281, 2019.

B. Tarai and P. Das, FilmArray ® meningitis/encephalitis (ME) panel, a rapid molecular platform for diagnosis of CNS infections in a tertiary care hospital in North India: one-and-half-year review, Neurol Sci, vol.40, pp.81-88, 2019.

H. Marchandin, V. Ventura, J. M. Alonso, and P. Van-de-perre, Mixed bacterial meningitis due to Streptococcus pneumoniae and Neisseria meningitidis in an 18-month-old child, J Clin Microbiol, vol.43, pp.1477-1479, 2005.

N. Sorek, S. Ashkenazi, G. Livni, and H. Ben-zvi, Neisseria meningitidis and cytomegalovirus simultaneous detection in the filmarray meningitis/encephalitis panel and its clinical relevance, IDCases, vol.17, p.516, 2019.

C. K. Lee, L. Chiu, G. Yan, K. L. Chew, B. Yan et al., False negative results caused by erroneous automated result interpretation algorithm on the FilmArray 2.0 instrument, Clin Chem Lab Med, vol.56, pp.43-45, 2018.

P. Gonzá-lez-donapetry, J. García-rodríguez, C. Bueno, and E. , A case of a FilmArray ® ME false negative in meningococcal meningitis, J Infect, 2019.

G. Piccirilli, A. Chiereghin, L. Gabrielli, M. Giannella, D. Squarzoni et al., Infectious meningitis/ encephalitis: evaluation of a rapid and fully automated multiplex PCR in the microbiological diagnostic workup, New Microbiol, vol.41, pp.118-125, 2018.

A. K. Slenker, T. L. Royer, and T. Villalobos, Human Herpes Virus 6 positivity on theFilmArray Meningitis/ Encephalitis needs clinical interpretation, Clin. Infect.Dis. Forthcoming, 2019.

A. C. Ericsdotter, M. Brink, M. Studahl, and M. Bengnér, Reactivation of herpes simplex type 1 in pneumococcal meningitis, J Clin Virol, vol.66, pp.100-102, 2015.

C. A. Gomez, B. A. Pinsky, A. Liu, and N. Banaei, Delayed diagnosis of tuberculous meningitis misdiagnosed as Herpes Simplex Virus-1 encephalitis with the FilmArray syndromic polymerase chain reaction panel, Open Forum Infect Dis, vol.4, p.245, 2016.

K. E. Hanson, The first fully automated molecular diagnostic panel for meningitis and encephalitis: how well does it perform, and when should it be used?, J Clin Microbiol, vol.54, pp.2222-2224, 2016.

S. Duff, R. Hasbun, C. C. Ginocchio, J. M. Balada-llasat, L. Zimmer et al., Economic analysis of rapid multiplex polymerase chain reaction testing for meningitis/encephalitis in pediatric patients, Future Microbiol, vol.13, pp.617-629, 2018.

D. K. Soucek, L. E. Dumkow, K. M. Vanlangen, and A. P. Jameson, Cost justification of the BioFire FilmArray Meningitis/Encephalitis panel versus standard of care for diagnosing meningitis in a community hospital, J Pharm Pract, vol.32, issue.1, pp.36-40, 2019.

R. Hasbun, J. M. Balada-llasat, and S. Duff, Letter to the Editor reply: economic model of the FilmArray Meningitis Encephalitis panel in children, Future Microbiol, vol.13, pp.1555-1556, 2018.