Janeway's Immunobiology (Garland Science, 2016. ,
Immunologic selftolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25): Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases, J Immunol, vol.155, pp.1151-1164, 1995. ,
Naturally arising Foxp3-expressing CD25 + CD4 + regulatory T cells in immunological tolerance to self and non-self, Nat Immunol, vol.6, pp.345-352, 2005. ,
Suppressor T cells, J Immunol, vol.108, pp.586-590, 1972. ,
A CD4 + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis, Nature, vol.389, pp.737-742, 1997. ,
How regulatory T cells work, Nat Rev Immunol, vol.8, pp.523-532, 2008. ,
Regulatory T cells in infection, Adv Immunol, vol.112, pp.73-136, 2011. ,
Roles of regulatory T cells in cancer immunity, Int Immunol, vol.28, pp.401-409, 2016. ,
Regulatory T cells in allergic diseases, J Allergy Clin Immunol, vol.138, pp.639-652, 2016. ,
The role of regulatory T cells in the biology of graftversus-host disease, Front Immunol, vol.4, p.163, 2013. ,
IL-10-producing and naturally occurring CD4 + Tregs: Limiting collateral damage, J Clin Invest, vol.114, pp.1372-1378, 2004. ,
IFN-? and CD46 stimulation are associated with active lupus and skew natural T regulatory cell differentiation to type 1 regulatory T (Tr1) cells, Proc Natl Acad Sci, vol.108, pp.18995-19000, 2011. ,
Qa-1 restriction of CD8 + suppressor T cells, J Clin Invest, vol.114, pp.1218-1221, 2004. ,
Control of regulatory T cell development by the transcription factor Foxp3, Science, vol.299, pp.1057-1062, 2003. ,
Transient expression of FOXP3 in human activated nonregulatory CD4 + T cells, Eur J Immunol, vol.37, pp.129-138, 2007. ,
Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function, J Transl Med, vol.7, p.89, 2009. ,
Human memory FOXP3 + Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t, Proc Natl Acad Sci, vol.106, pp.8635-8640, 2009. ,
IL-17-producing human peripheral regulatory T cells retain suppressive function, Blood, vol.113, pp.4240-4249, 2009. ,
Conversion of peripheral CD4 + CD25 ? naive T cells to CD4 + CD25 + regulatory T cells by TGF-? induction of transcription factor Foxp3, J Exp Med, vol.198, pp.1875-1886, 2003. ,
IL-2 is essential for TGF-beta to convert naive CD4 + CD25 ? cells to CD25 + Foxp3 + regulatory T cells and for expansion of these cells, J Immunol, vol.178, pp.2018-2027, 2007. ,
Cell-based therapies with T regulatory cells, BioDrugs, vol.31, pp.335-347, 2017. ,
CD4 + CD25 high regulatory cells in human peripheral blood, J Immunol, vol.167, pp.1245-1253, 2001. ,
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression, J Exp Med, vol.204, pp.1257-1265, 2007. ,
Extracellular adenosine-mediated modulation of regulatory T cells, Front Immunol, vol.5, p.304, 2014. ,
Characterization of adenosine deaminase binding to human CD26 on T cells and its biologic role in immune response, J Immunol, vol.156, pp.1349-1355, 1996. ,
CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines, Proc Natl Acad Sci, vol.86, pp.1333-1337, 1989. ,
Interleukins-1? and -6 but not transforming growth factor-? are essential for the differentiation of interleukin-17-producing human T helper cells, Nat Immunol, vol.8, pp.942-949, 2007. ,
Activation of human CD4 + cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype, Nature, vol.421, pp.388-392, 2003. ,
Forcing cells to change lineages, Nature, vol.462, pp.587-594, 2009. ,
DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells, Eur J Immunol, vol.37, pp.2378-2389, 2007. ,
Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood, J Exp Med, vol.193, pp.1285-1294, 2001. ,
Interindividual variation in human T regulatory cells, Proc Natl Acad Sci, vol.111, pp.1111-1120, 2014. ,
Monitoring regulatory T cells in clinical samples: Consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry, Cancer Immunol Immunother, vol.64, pp.1271-1286, 2015. ,
Immune reconstitution after allogeneic hematopoietic stem cell transplantation, Front Immunol, vol.7, p.507, 2016. ,
Regulatory T cells and autoimmune disease, Immunol Rev, vol.204, pp.195-207, 2005. ,
First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4 + CD25 + CD127 ? T regulatory cells, Clin Immunol, vol.133, pp.22-26, 2009. ,
Generation and accumulation of immunosuppressive adenosine by human CD4 + CD25 high FOXP3 + regulatory T cells, J Biol Chem, vol.285, pp.7176-7186, 2010. ,