P. Medina, M. R. Paillasse, G. Segala, M. Voisin, L. Mhamdi et al., Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties, Nat. Commun, vol.4, p.1840, 2013.
URL : https://hal.archives-ouvertes.fr/inserm-00823974

M. Bauriaud-mallet, L. Vija-racaru, S. Brillouet, A. Mallinger, P. Medina et al., The cholesterol-derived metabolite dendrogenin A functionally reprograms breast adenocarcinoma and undifferentiated thyroid cancer cells, J. Steroid Biochem. Mol. Biol, vol.192, p.105390, 2019.
URL : https://hal.archives-ouvertes.fr/inserm-02380538

S. Silvente-poirot, F. Dalenc, and M. Poirot, The effects of cholesterol-derived oncometabolites on nuclear receptor function in Cancer, Cancer Res, vol.78, pp.4803-4808, 2018.
URL : https://hal.archives-ouvertes.fr/inserm-02380550

M. Poirot and S. Silvente-poirot, The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers, Biochem. Pharmacol, vol.153, pp.75-81, 2018.

M. Voisin, P. Medina, A. Mallinger, F. Dalenc, E. Huc-claustre et al., Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor, Proc. Natl. Acad. Sci. U. S. A, vol.114, pp.9346-9355, 2017.
URL : https://hal.archives-ouvertes.fr/hal-02316171

G. Segala, M. David, P. Medina, M. C. Poirot, N. Serhan et al., Nat. Commun, vol.8, p.1903, 2017.

F. Dalenc, M. Poirot, and S. Silvente-poirot, Dendrogenin a: a mammalian metabolite of cholesterol with tumor suppressor and neurostimulating properties, Curr. Med. Chem, vol.22, pp.3533-3549, 2015.

S. Silvente-poirot and M. Poirot, the balance, vol.343, pp.1445-1446, 2014.
URL : https://hal.archives-ouvertes.fr/inserm-00968924

S. A. Khalifa, P. Medina, A. Erlandsson, H. R. El-seedi, S. Silvente-poirot et al., The novel steroidal alkaloids dendrogenin A and B promote proliferation of adult neural stem cells, Biochem. Biophys. Res. Commun, vol.446, pp.681-686, 2014.
URL : https://hal.archives-ouvertes.fr/inserm-00968932

P. Medina, M. R. Paillasse, B. Payre, S. Silvente-poirot, and M. Poirot, Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases, J. Med. Chem, vol.52, pp.7765-7777, 2009.
URL : https://hal.archives-ouvertes.fr/inserm-00519151

S. Silvente-poirot, G. Segala, M. C. Poirot, and M. Poirot, Ligand-dependent transcriptional induction of lethal autophagy: a new perspective for cancer treatment, Autophagy, vol.14, pp.555-557, 2018.

M. Poirot, R. Soules, A. Mallinger, F. Dalenc, and S. , Silvente-Poirot, Chemistry, biochemistry, metabolic fate and mechanism of action of 6-oxo-cholestan-3be-ta,5alpha-diol (OCDO), a tumor promoter and cholesterol metabolite, Biochimie, vol.153, pp.139-149, 2018.

A. Fransson, P. Medina, M. R. Paillasse, S. Silvente-poirot, M. Poirot et al., Dendrogenin A and B two new steroidal alkaloids increasing neural responsiveness in the deafened guinea pig, Front. Aging Neurosci, vol.7, p.145, 2015.

S. Silvente-poirot, P. Medina, M. Record, M. Poirot, R. From-tamoxifen-to et al., Journal of Steroid Biochemistry and Molecular Biology, vol.194, p.105447, 2019.

, A: the discovery of a mammalian tumor suppressor and cholesterol metabolite, Biochimie, vol.130, pp.109-114, 2016.

M. Poirot and S. Silvente-poirot, When cholesterol meets histamine, it gives rise to dendrogenin A: a tumour suppressor metabolite, Biochem. Soc. Trans, vol.44, pp.631-637, 2016.

E. G. Bligh and W. J. Dyer, A rapid method of total lipid extraction and purification, Can. J. Biochem. Physiol, vol.37, pp.911-917, 1959.

E. Noguer, R. Soules, C. Netter, C. Nagarathinam, J. Leignadier et al., Quantitative analysis of the tumor suppressor dendrogenin A using liquid chromatography tandem mass spectrometry, Chem. Phys. Lipids, vol.207, pp.81-86, 2017.

B. Buszewski and S. Noga, Hydrophilic interaction liquid chromatography (HILIC)-a powerful separation technique, Anal. Bioanal. Chem, vol.402, pp.231-247, 2012.

F. Qin, Y. Y. Zhao, M. B. Sawyer, and X. F. Li, Hydrophilic interaction liquid chromatography-tandem mass spectrometry determination of estrogen conjugates in human urine, Anal. Chem, vol.80, pp.3404-3411, 2008.

K. M. Hines, J. Herron, and L. Xu, Assessment of altered lipid homeostasis by HILIC-ion mobility-mass spectrometry-based lipidomics, J. Lipid Res, vol.58, pp.809-819, 2017.

J. Chen, L. Chen, M. Li, and Y. Sun, Quantitative determination of six steroid alkaloids by sensitive hydrophilic interaction liquid chromatography electrospray ionization mass spectrometry and its application to pharmacokinetic study in rats, Biomed. Chromatogr, vol.33, p.4377, 2019.

M. M. Bradford, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem, vol.72, pp.248-254, 1976.

N. F. Bouzas, S. Dresen, B. Munz, and W. Weinmann, Determination of basic drugs of abuse in human serum by online extraction and LC-MS/MS, Anal. Bioanal. Chem, vol.395, pp.2499-2507, 2009.

R. J. Meeters and S. Voswinkel, Bioanalytical method development and validation: from the USFDA 2001 to the USFDA 2018 guidance for industry, J Appl Bioanal, vol.4, pp.67-73, 2018.

M. N. Paludetto, F. Puisset, F. L. Louedec, B. Allal, T. Lafont et al., Simultaneous monitoring of pazopanib and its metabolites by UPLC-MS/MS, J. Pharm. Biomed. Anal, vol.154, pp.373-383, 2018.

D. Beauvais, J. F. Goossens, E. Boyle, B. Allal, T. Lafont et al., Development and validation of an UHPLC-MS/MS method for simultaneous quantification of ibrutinib and its dihydrodiol-metabolite in human cerebrospinal fluid, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci, pp.158-166, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02178925

J. Ma, J. Shi, H. Le, R. Cho, J. C. Huang et al., A fully automated plasma protein precipitation sample preparation method for LC-MS/MS bioanalysis, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci, vol.862, pp.219-226, 2008.

M. R. Paillasse, N. Saffon, H. Gornitzka, S. Silvente-poirot, M. Poirot et al., Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles, J. Lipid Res, vol.53, pp.718-725, 2012.
URL : https://hal.archives-ouvertes.fr/inserm-00743457