, ROS, reactive oxygen species

E. Er and . Reticulum,

, CDDP

, H 2 DCFDA, 2?,7?-dichlorodihydrofluorescein diacetate; TrxR

. Edta,

, NEAA, nonessential amino acids; FBS, fetal bovine serum

D. Dmem, s modified eagle's medium; BME, basal medium eagle; NMR, nuclear magnetic resonance; ESI-MS, electrospray ionization-mass spectrometry; RP-HPLC, reverse phase-high-performance liquid chromatography; DMSO-d 6 , deuterated dimethyl sulfoxide; MeOH-d 4 , deuterated methanol; ddH 2 O, ultrapure water; ICP-OES, inductively couple plasma-optical emission spectrometry, ICP-MS

. Nadph,

, DTNB, vol.5, issue.2, p.5

, UPR, unfolded protein response

R. Ras, , pp.arene Schiff-base

T. Tpb, Bcl-2, B-cell lymphoma 2; Bcl-x L , B-cell lymphoma extra large; BAX, bcl-2-associated X protein

, CCAAT-enhancer-binding protein homologous protein; PERK, PKR-like ER kinase

. Ire1?, inositol-requiring enzyme 1A; ATF6, activating transcription factor 6; eif2?, eukaryotic translation initiation factor 2A; HBSS, Hank's balanced salt solution

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