Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation, Proc. Natl. Acad. Sci. USA, vol.87, pp.5935-5939, 1990. ,
,
Gene expression and localization of opioid peptides in immune cells of inflamed tissue: functional role in antinociception, Neuroscience, vol.48, pp.491-500, 1992. ,
Peripheral mechanisms of opioid antinociception in inflammation: involvement of cytokines, Eur. J. Pharmacol, vol.242, pp.229-235, 1993. ,
Interleukin 1? and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue, Proc. Natl. Acad. Sci. USA, vol.91, pp.4219-4223, 1994. ,
,
, Local upregulation of CRH and IL-1 receptors in inflamed tissue and local CRH-and IL-1?-induced antinociception, Eur. J. Pharmacol, vol.311, pp.221-231
The role of endogenous opioids and their receptors in the immune system, Proc. Soc. Exp. Biol. Med, vol.198, pp.710-720, 1991. ,
No tolerance to peripheral morphine analgesia in presence of opioid expression in inflamed synovia, J. Clin. Invest, vol.98, pp.793-799, 1996. ,
Substance P release from knee joint afferent terminals: modulation by opioids, Brain Res, vol.458, pp.319-324, 1988. ,
The control of pain in peripheral tissue by opioids, N. Engl. J. Med, vol.332, pp.1685-1690, 1995. ,
Intrinsic mechanisms of antinociception in inflammation: local opioid receptors and beta-endorphin, J. Neurosci, vol.10, pp.1292-1298, 1990. ,
Newcastle disease virus-infected splenocytes express the proopiomelanocortin gene, J. Exp. Med, vol.163, pp.1589-1594, 1986. ,
?-endorphin: cytokine and neuropeptide, Immunol. Rev, vol.119, pp.41-63, 1991. ,
What do we know about the expression of proopiomelanocortin transcripts and related peptides in lymphoid tissue?, Endocrinology, vol.133, pp.1921-1921, 1993. ,
Homing of naive, memory and effector lymphocytes, Curr. Opin. Immunol, vol.5, pp.423-427, 1993. ,
Peptidases in the CNS: formation of biologically active, receptor-specific peptide fragments, Crit. Rev. Neurobiol, vol.7, pp.163-174, 1993. ,
, , 1995.
, Active ?-endorphin metabolites generated by T-cell ectopeptidases, The Brain Immune Axis and Substance, pp.49-56
Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: alterations in behavior and nociceptive thresholds, Pharmacol. Biochem. Behav, vol.31, pp.455-451, 1988. ,
Migration pathways of CD4 T cell subsets in vivo: the CD45RC-subset enters the thymus via alpha 4 integrin-VCAM-1 interaction, Int. Immunol, vol.7, pp.1861-1871, 1995. ,
Lymphocyte interactions with extracellular matrix, Exp. Biol.) J, vol.5, pp.2292-2299, 1991. ,
Altered patterns of T cell migration through lymph nodes and skin following antigen challenge, Eur. J. Immunol, vol.22, pp.2205-2210, 1992. ,
Migration of so-called naive and memory T lymphocytes from blood to lymph in the rat. The influence of IFN-gamma on the circulation pattern, J. Immunol, vol.152, pp.1744-1750, 1994. ,
Expression of corticotropin-releasing factor in inflamed tissue is required for intrinsic peripheral opioid analgesia, Proc. Natl. Acad. Sci. USA, vol.93, pp.6090-6100, 1996. ,
Structure and Physiology of the Slow Inward Calcium Channel, In Receptor Biochemistry and Methodology, vol.9, pp.161-246, 1987. ,
Role of B7 signaling in the differentiation of naive CD4 ? T cells to effector interleukin-4-producing T helper cells, Immunol. Res, vol.14, pp.176-188, 1995. ,
Opioid receptors and endogenous opioid peptides, Med. Res. Rev, vol.11, pp.357-374, 1991. ,