Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis, Nature, vol.399, pp.809-813, 1999. ,
Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies, Oncogene, vol.6, pp.1699-1703, 1991. ,
Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro, Int. J. Cancer, vol.46, pp.839-844, 1990. ,
Induction of the growth inhibitor IGF-binding protein 3 by p53, Nature, vol.377, pp.646-649, 1995. ,
Thermodynamic stability of wild-type and mutant p53 core domain, Proc. Natl. Acad. Sci. USA, vol.94, pp.14338-14342, 1997. ,
Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy, Oncogene, vol.19, pp.1245-1256, 2000. ,
Different p73 splicing variants are expressed in distinct tumour areas of a multifocal neuroblastoma, Cell Death Differ, vol.6, pp.391-393, 1999. ,
, Cell, vol.99, pp.143-153, 1999.
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells, Genes Dev, vol.10, pp.2438-2451, 1996. ,
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations, Science, vol.265, pp.346-355, 1994. ,
High level expression of deltaN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)?, Oncogene, vol.19, pp.3439-3444, 2000. ,
Arrowsmith. 1999. p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53, J. Biol. Chem, vol.274, pp.18709-18714 ,
Two new p73 splice variants, gamma and delta, with different transcriptional activity, J. Exp. Med, vol.188, pp.1763-1768, 1998. ,
p73 function is inhibited by tumor-derived p53 mutants in mammalian cells, Mol. Cell. Biol, vol.19, pp.1438-1449, 1999. ,
URL : https://hal.archives-ouvertes.fr/inserm-02360310
Variable expression and absence of mutations in p73 in primary neuroblastoma tumors argues against a role in neuroblastoma development, Int. J. Mol. Med, vol.3, pp.585-589, 1999. ,
Definition of a consensus binding site for p53, Nat. Genet, vol.1, pp.45-49, 1992. ,
Genomic effects of the putative oncogene G alpha s: chronic transcriptional activation of the c-fos proto-oncogene in endocrine cells, J. Biol. Chem, vol.269, pp.22663-22671, 1994. ,
Activating mutations in p53 produce a common conformational effect: a monoclonal antibody specific for the mutant form, EMBO J, vol.9, pp.1595-1602, 1990. ,
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage, Nature, vol.399, pp.806-809, 1999. ,
, Biochim. Biophys. Acta, vol.1287, pp.77-102, 1996.
Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA, EMBO J, vol.12, pp.1021-1028, 1993. ,
Expression of the p53 homologue p63alpha and deltaNp63alpha in normal and neoplastic cells, Carcinogenesis, vol.21, pp.153-160, 2000. ,
Infrequent somatic mutations of the p73 gene in various human cancers, Eur. J. Surg. Oncol, vol.25, pp.194-198, 1999. ,
Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines, Mol. Cell. Biol, vol.7, pp.2863-2869, 1987. ,
Split-hand/split-foot malformation is caused by mutations in the p63 gene on 3q27, Am. J. Hum. Genet, vol.67, pp.59-66, 2000. ,
Caput, and A. Nakagawara. 1999. p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent, Oncogene, vol.18, pp.1061-1066 ,
Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus, Cell, vol.81, pp.1021-1029, 1995. ,
Functional dissection of p53 tumor suppressor protein, Methods Enzymol, vol.283, pp.245-256, 1997. ,
p73 is a human p53-related protein that can induce apoptosis, Nature, vol.389, pp.191-194, 1997. ,
Another p53 Doppelganger?, Science, vol.281, pp.57-58, 1998. ,
,
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers, Cell, vol.90, pp.809-819, 1997. ,
p53: puzzle and paradigm, Genes Dev, vol.10, pp.1054-1072, 1996. ,
Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastoma tumors and cell lines, Cell Growth Differ, vol.9, pp.897-903, 1998. ,
Mutations in p53 produce a common conformational effect that can be detected with a panel of monoclonal antibodies directed toward the central part of the p53 protein, Oncogene, vol.9, pp.3689-3694, 1994. ,
p53, the cellular gatekeeper for growth and division, Cell, vol.88, pp.323-331, 1997. ,
The p53/p63/p73 family of transcription factors: overlapping and distinct functions, J. Cell Sci, vol.113, pp.1661-1670, 2000. ,
A common polymorphism acts as an intragenic modifier of mutant p53 behaviour, Nat. Genet, vol.25, pp.47-54, 2000. ,
p63 is a p53 homologue required for limb and epidermal morphogenesis, Nature, vol.398, pp.708-713, 1999. ,
Different forms of p53 detected by monoclonal antibodies in non-dividing and dividing lymphocytes, Nature, vol.310, pp.143-145, 1984. ,
Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation, Cell, vol.65, pp.765-774, 1991. ,
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene, Cell, vol.80, pp.293-299, 1995. ,
Ping, and A. Nakagawara. 1998. p73, a gene related to p53, is not mutated in esophageal carcinomas, Int. J. Cancer, vol.78, pp.437-440 ,
Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers, Cancer Res, vol.58, pp.1380-1383, 1998. ,
Characterization of the expression pattern of p63alpha and deltanp63alpha in benign and malignant oral epithelial lesions, Int. J. Cancer, vol.87, pp.368-372, 2000. ,
A role of cyclin G in the process of apoptosis, Oncogene, vol.18, pp.4606-4615, 1999. ,
Lonely no more: p53 finds its kin in a tumor suppressor haven, Cell, vol.90, pp.829-832, 1997. ,
Cloning and functional analysis of human p51, which structurally and functionally resembles p53, Nat. Med, vol.4, pp.839-843, 1998. ,
Frequent alteration of p63 expression in human primary bladder carcinomas, Cancer Res, vol.60, pp.3370-3374, 2000. ,
Specific interaction between the p53 cellular tumour antigen and major heat shock proteins, Nature, vol.320, pp.182-184, 1986. ,
Tumor-derived mutations within the DNA-binding domain of p53 that phenotypically resemble the deletion of the proline-rich domain, Oncogene, vol.19, pp.1834-1842, 2000. ,
A novel protein with strong homology to the tumor suppressor p53, Oncogene, vol.15, pp.1363-1367, 1997. ,
,
A second p53-related protein, p73L, with high homology to p73, Biochem. Biophys. Res. Commun, vol.248, pp.603-607, 1998. ,
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites, Genes Dev, vol.14, pp.289-300, 2000. ,
Experiments with gene fusions, 1984. ,
Physical and functional interaction between p53 mutants and different isoforms of p73, J. Biol. Chem, vol.275, pp.29503-29512, 2000. ,
Mutational analysis of the p73 gene localized at chromosome 1p36.3 in colorectal carcinomas, Int. J. Oncol, vol.13, pp.319-323, 1998. ,
Expression of p73 and its relation to histopathology and prognosis in hepatocellular carcinoma, J. Natl. Cancer Inst, vol.91, pp.1154-1158, 1999. ,
Conformational changes in p53 analysed using new antibodies to the core DNA binding domain of the protein, Oncogene, vol.10, pp.389-393, 1995. ,
DNA damage enables p73, Nature, vol.399, pp.734-737, 1999. ,
Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma, Int. J. Cancer, vol.86, pp.684-689, 2000. ,
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities, Mol. Cell, vol.2, pp.305-316, 1998. ,
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development, Nature, vol.398, pp.714-718, 1999. ,
p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours, Nature, vol.404, pp.99-103, 2000. ,
Overexpression of the wild type p73 gene in human bladder cancer, Oncogene, vol.18, pp.1629-1633, 1999. ,
Alterations of p73 preferentially occur in gastric adenocarcinomas with foveolar epithelial phenotype, Int. J. Cancer, vol.83, pp.192-196, 1999. ,
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage, Nature, vol.399, pp.814-817, 1999. ,
Overexpression of the wild type p73 gene in breast cancer tissues and cell lines, Cancer Res, vol.59, pp.3257-3263, 1999. ,
Altered conformation of the p53 protein in myeloid leukemia cells and mitogenstimulated normal blood cells, Oncogene, vol.7, pp.1645-1647, 1992. ,
The potential tumor suppressor p73 differentially regulates cellular p53 target genes, Cancer Res, vol.58, pp.5061-5065, 1998. ,