Alternative isoform regulation in human tissue transcriptomes, Nature, vol.456, pp.470-476, 2008. ,
Expansion of the eukaryotic proteome by alternative splicing, Nature, vol.463, pp.457-463, 2010. ,
Cotranscriptional exon skipping in the genotoxic stress response, Nat Struct Mol Biol, vol.17, pp.1358-1366, 2010. ,
Alternative splicing: global insights, FEBS J, vol.277, pp.856-866, 2010. ,
Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged, Genes Dev, vol.24, pp.2343-2364, 2010. ,
Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications, Cell Mol Life Sci, vol.61, pp.2189-2199, 2004. ,
Splice variants in apoptotic pathway, Exp Oncol, vol.34, pp.212-217, 2012. ,
Regulation of apoptosis by alternative pre-mRNA splicing, Mol Cell, vol.19, pp.1-13, 2005. ,
Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics, Nat Rev Mol Cell Biol, vol.5, pp.89-99, 2004. ,
The multiple lives of NMD factors: balancing roles in gene and genome regulation, Nat Rev Genet, vol.9, pp.699-712, 2008. ,
Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array, BMC Genomics, vol.7, p.325, 2006. ,
Normal colon epithelium: a dataset for the analysis of gene expression and alternative splicing events in colon disease, BMC Genomics, vol.11, p.5, 2010. ,
Next-generation sequencing in the clinic: promises and challenges, Cancer Lett, vol.340, pp.248-295, 2012. ,
RNA-Seq: a revolutionary tool for transcriptomics, Nat Rev Genet, vol.10, pp.57-63, 2009. ,
Transcriptome analysis using next-generation sequencing, Curr Opin Biotechnol, vol.24, pp.22-30, 2013. ,
A comprehensive evaluation of alignment algorithms in the context of RNA-Seq, PLoS ONE, vol.7, p.52403, 2012. ,
Differential analysis of gene regulation at transcript resolution with RNA-seq, Nat Biotechnol, vol.31, pp.46-53, 2012. ,
Human transcriptome array for highthroughput clinical studies, Proc Natl Acad Sci, vol.108, pp.3707-3712, 2011. ,
Converting a breast cancer microarray signature into a high-throughput diagnostic test, BMC Genomics, vol.7, p.278, 2006. ,
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer, N Engl J Med, vol.353, pp.1673-1684, 2005. ,
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer, N Engl J Med, vol.353, pp.1659-1672, 2005. ,
de Vos AM: VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface, Structure, vol.6, pp.1153-1167, 1998. ,
The splice variants of vascular endothelial growth factor (VEGF) and their receptors, J Cell Sci, vol.114, pp.853-865, 2001. ,
VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma, Cancer Res, vol.62, pp.4123-4131, 2002. ,
Alternative splicing in angiogenesis: the vascular endothelial growth factor paradigm, Cancer Lett, vol.249, pp.133-142, 2007. ,
The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo, Oncogene, vol.29, pp.5392-5403, 2010. ,
The splicing factor SC35 has an active role in transcriptional elongation, Nat Struct Mol Biol, vol.15, pp.819-826, 2008. ,
Abnormal expression of the pre-mRNA splicing regulators SRSF1, SRSF2, SRPK1 and SRPK2 in non small cell lung carcinoma, PLoS ONE, vol.7, p.46539, 2012. ,
URL : https://hal.archives-ouvertes.fr/inserm-02337424
Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways, RNA, vol.1, pp.335-346, 1995. ,
Gene set enrichment analysis of RNA-Seq data: integrating differential expression and splicing, BMC Bioinforma, vol.14, p.16, 2013. ,
NURD: an implementation of a new method to estimate isoform expression from non-uniform RNA-seq data, BMC Bioinforma, vol.14, p.220, 2013. ,
Differential detection of alternatively spliced variants of Ciz1 in normal and cancer cells using a custom exon-junction microarray, BMC Cancer, vol.10, p.482, 2010. ,
Therapeutic potential of inhibitory VEGF splice variants, Future Oncol, vol.1, pp.467-473, 2005. ,
VEGF-A splicing: the key to anti-angiogenic therapeutics?, Nat Rev Cancer, vol.8, pp.880-887, 2008. ,
Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis, J Biol Chem, vol.285, pp.5532-5540, 2010. ,
The antiangiogenic isoforms of VEGF in health and disease, Biochem Soc Trans, vol.37, pp.1207-1213, 2009. ,
VEGF spliced variants: possible role of antiangiogenesis therapy, J Nucleic Acids, p.162692, 2012. ,
EGFR soluble isoforms and their transcripts are expressed in meningiomas, PLoS One, vol.7, p.37204, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00872638
Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity, Neoplasia, vol.13, pp.461-471, 2011. ,
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing, Cell, vol.150, pp.1107-1120, 2012. ,
VEGF165b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro-and antiangiogenic VEGF-A isoforms has implications for therapy, Br J Cancer, vol.98, pp.1366-1379, 2008. ,
New analysis workflow for MALDI imaging mass spectrometry: application to the discovery and identification of potential markers of childhood absence epilepsy, J Proteome Res, vol.11, pp.5453-5463, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00877728
, Topoisomerase I and II inhibitors control, p.2
URL : https://hal.archives-ouvertes.fr/hal-02262420
RNA splicing in human cells, Mol Cancer Res, vol.2, pp.53-61, 2004. ,
E2F1 induces apoptosis and sensitizes human lung adenocarcinoma cells to death-receptor-mediated apoptosis through specific downregulation of c-FLIPshort, Cell Death Differ, vol.13, pp.260-272, 2006. ,
E2F1, Skp2 and cyclin E oncoproteins are upregulated and directly correlated in high-grade neuroendocrine lung tumors, Oncogene, vol.26, pp.6927-6936, 2007. ,
URL : https://hal.archives-ouvertes.fr/inserm-00173067
Gene-and exon-expression profiling reveals an extensive LPS-induced response in immune cells in patients with cirrhosis, J Hepatol, vol.58, pp.936-948, 2013. ,
Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F, PLoS ONE, vol.7, p.51266, 2012. ,
Analysis of relative gene expression data using real-time quantitative PCR and the 2 ? ??CT method, Methods, vol.25, pp.402-408, 2001. ,
A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies, Molecular Cancer, vol.13, p.9, 2014. ,
URL : https://hal.archives-ouvertes.fr/inserm-00935318