Retroelements and the human genome: new perspectives on an old relation, Proc Natl Acad Sci, pp.14572-14581, 2004. ,
Comprehensive analysis of human endogenous retrovirus transcriptional activity in human tissues with a retrovirus-specific microarray, J Virol, vol.79, pp.341-52, 2005. ,
Human endogenous retrovirus expression profiles in samples from brains of patients with schizophrenia and bipolar disorders, J Virol, vol.79, pp.10890-901, 2005. ,
Endogenous retrovirus type W GAG and envelope protein antigenemia in serum of schizophrenic patients, Biol Psychiatry, vol.64, pp.1019-1042, 2008. ,
Implication of human endogenous retroviruses in the development of autoimmune diseases, Int Rev Immunol, vol.29, pp.351-70, 2010. ,
An ancestral retroviral protein identified as a therapeutic target in type-1 diabetes, JCI Insight, vol.2, p.94387, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-02059891
Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis, Ann Neurol, vol.69, pp.141-51, 2011. ,
Human endogenous retrovirus-K contributes to motor neuron disease, Sci Transl Med, vol.7, pp.307-153, 2015. ,
Leptomeningeal cell line from multiple sclerosis with reverse transcriptase activity and viral particles, Res Virol, vol.140, pp.551-61, 1989. ,
Isolation of retrovirus from patients with multiple sclerosis, Lancet, vol.337, pp.862-865, 1991. ,
Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. the collaborative research group on multiple sclerosis, Proc Natl Acad Sci, vol.94, pp.7583-7591, 1997. ,
Retrovirus-like particles in an Epstein-Barr virus-producing cell line derived from a patient with chronic progressive myelopathy, Acta Neurol Scand, vol.87, pp.71-77, 1993. ,
Multiple sclerosis-associated retrovirus (MSRV) in Sardinian MS patients, Neurology, vol.58, pp.471-474, 2002. ,
Detection of virion-associated MSRV-RNA in serum of patients with multiple sclerosis, Lancet, vol.351, p.33, 1998. ,
Multiple sclerosis-associated retrovirus in early multiple sclerosis: a sixyear follow-up of a Sardinian cohort, Mult Scler, vol.12, pp.698-703, 2006. ,
Human endogenous retroviruses in neurological diseases, Trends Mol Med, vol.24, pp.379-94, 2018. ,
Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen, Immunity, vol.15, pp.579-89, 2001. ,
Expression and activation by Epstein Barr virus of human endogenous retroviruses-W in blood cells and astrocytes: inference for multiple sclerosis, PLoS ONE, vol.7, p.44991, 2012. ,
HHV-6A infection induces expression of HERV-K18-encoded superantigen, J Clin Virol, vol.46, pp.47-55, 2009. ,
Human herpesvirus-6B induces expression of the human endogenous retrovirus K18-encoded superantigen, J Clin Virol, vol.46, pp.15-24, 2009. ,
Epstein-Barr virus and multiple sclerosis. From evidence to therapeutic strategies, J Neurol Sci, vol.361, pp.213-222, 2016. ,
Relationship of human herpes virus 6 and multiple sclerosis: A systematic review and meta-analysis, J Cell Physiol, vol.233, pp.2850-62, 2018. ,
CD46 is a cellular receptor for human herpesvirus 6, Cell, vol.99, pp.817-844, 1999. ,
Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b, J Exp Med, vol.163, pp.837-55, 1986. ,
The CD46-Jagged1 interaction is critical for human TH1 immunity, Nat Immunol, vol.13, pp.1213-1234, 2012. ,
Human Herpesvirus 6 and Neuroinflammation, ISRN Virol, p.834890, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-00972063
Four viruses, two bacteria, and one receptor: membrane cofactor protein (CD46) as pathogens' magnet, J Virol, vol.78, pp.4385-4393, 2004. ,
HTLV-1 propels thymic human T cell development in "human immune system" Rag2 ? / ? gamma c ? / ? mice, PLoS Pathog, vol.7, 2011. ,
SLAM (CD150)-independent measles virus entry as revealed by recombinant virus expressing green fluorescent protein, J Virol, vol.76, pp.6743-6752, 2002. ,
Recovery of pathogenic measles virus from cloned cDNA, J Virol, vol.74, pp.6643-6650, 2000. ,
Multiple isoforms of CD46 (membrane cofactor protein) serve as receptors for measles virus, Proc Natl Acad Sci USA, vol.91, pp.2161-2166, 1994. ,
Mapping of the primary binding site of measles virus to its receptor CD46, J Biol Chem, vol.272, pp.22072-22081, 1997. ,
A monoclonal antibody recognizes a human cell surface glycoprotein involved in measles virus binding, J Gen Virol, pp.2617-2641, 1992. ,
Monoclonal antibody GB24 recognizes a trophoblast-lymphocyte cross-reactive antigen, Am J Reprod Immunol Microbiol, vol.18, pp.21-28, 1988. ,
The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3, J Virol, vol.78, pp.4454-62, 2004. ,
Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation, Nat Immunol, vol.3, pp.659-66, 2002. ,
URL : https://hal.archives-ouvertes.fr/hal-02322420
Amplification of the antibody response by C3b complexed to antigen through an ester link, J Immunol, vol.162, pp.3647-52, 1999. ,
Preclinical and early clinical development of GNbAC1, a humanized IgG4 monoclonal antibody targeting endogenous retroviral MSRV-Env protein, mAbs, vol.7, pp.265-75, 2015. ,
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C, J Biol Chem, vol.266, pp.15771-81, 1991. ,
Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis, Proc Natl Acad Sci, vol.102, pp.7736-7777, 2005. ,
Autophagy induction by the pathogen receptor CD46, Cell Host Microbe, vol.6, pp.354-66, 2009. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00456148
Novel reliable real-time PCR for differential detection of MSRVenv and syncytin-1 in RNA and DNA from patients with multiple sclerosis, J Virol Methods, vol.161, pp.98-106, 2009. ,
Analysis of relative gene expression data using realtime quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods San Diego Calif, vol.25, pp.402-410, 2001. ,
Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis, J Clin Invest, vol.116, pp.3252-3259, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-02322380
The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments, Clin Chem, vol.55, pp.611-633, 2009. ,
CD134 is a cellular receptor specific for human herpesvirus-6B entry, Proc Natl Acad Sci, vol.110, pp.9096-9105, 2013. ,
Human herpesvirus 6 and measles virus employ distinct CD46 domains for receptor function, J Biol Chem, vol.277, pp.39112-39120, 2002. ,
Contribution of the repeating domains of membrane cofactor protein (CD46) of the complement system to ligand binding and cofactor activity, J Immunol, vol.147, pp.3005-3016, 1991. ,
Dissecting sites important for complement regulatory activity in membrane cofactor protein (MCP; CD46), J Biol Chem, vol.275, pp.37692-701, 2000. ,
CD46: the "multitasker" of complement proteins, Int J Biochem Cell Biol, vol.45, pp.2808-2828, 2013. ,
Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation, Proc Natl Acad Sci, vol.103, pp.18685-90, 2006. ,
CD46/CD3 costimulation induces morphological changes of human T cells and activation of Vav, Rac, and extracellular signal-regulated kinase mitogen-activated protein kinase, J Immunol, vol.167, pp.6780-6785, 2001. ,
URL : https://hal.archives-ouvertes.fr/hal-02322447
Membrane cofactor protein (MCP; CD46): isoform-specific tyrosine phosphorylation, J Immunol, vol.164, pp.1839-1885, 2000. ,
Emerging roles and new functions of CD46, Springer Semin Immunopathol, vol.27, pp.345-58, 2005. ,
Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4, Int Immunol, vol.27, pp.545-53, 2015. ,
URL : https://hal.archives-ouvertes.fr/inserm-01163817
Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation, Ann Neurol, vol.74, pp.721-753, 2013. ,
The envelope protein of a human endogenous retrovirus-W family activates innate immunity through CD14/TLR4 and promotes Th1-like responses, J Immunol, vol.176, pp.7636-7680, 2006. ,
URL : https://hal.archives-ouvertes.fr/inserm-00000108
MSRV envelope protein is a potent, endogenous and pathogenic agonist of human toll-like receptor 4: relevance of GNbAC1 in multiple sclerosis treatment, J Neuroimmunol, vol.291, pp.29-38, 2016. ,
Cutting edge: epstein-barr virus transactivates the HERV-K18 superantigen by docking to the human complement receptor 2 (CD21) on primary B cells, J Immunol, vol.177, pp.2056-60, 2006. ,
Non-random pairing of CD46 isoforms with skewing towards BC2 and C2 in activated and memory/effector T cells, Sci Rep, vol.6, p.35406, 2016. ,
Preferential activation of Toll-like receptor nine by CD46-utilizing adenoviruses, J Virol, vol.81, pp.1305-1317, 2007. ,
Efficient major histocompatibility complex class IIrestricted presentation of measles virus relies on hemagglutinin-mediated targeting to its cellular receptor human CD46 expressed by murine B cells, J Exp Med, vol.179, pp.353-361, 1994. ,
Enhanced MHC class II-restricted presentation of measles virus (MV) hemagglutinin in transgenic mice expressing human MV receptor CD46, Eur J Immunol, vol.28, pp.1301-1315, 1998. ,
CD46 is phosphorylated at tyrosine 354 upon infection of epithelial cells by Neisseria gonorrhoeae, J Cell Biol, vol.156, pp.951-958, 2002. ,
A functional interaction between CD46 and DLG4: a role for DLG4 in epithelial polarization, J Biol Chem, vol.277, pp.4477-84, 2002. ,
Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells, Nat Immunol, vol.11, pp.862-71, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-00564091
Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA, Nat Med, vol.3, pp.1394-1401, 1997. ,
Human Herpesvirus-6 (HHV-6) infection in multiple sclerosis: a preliminary report, Mult Scler Houndmills Basingstoke Engl, vol.4, pp.490-496, 1998. ,
Correlation between HHV-6 reactivation and multiple sclerosis disease activity, J Med Virol, vol.69, pp.111-118, 2003. ,
Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease, Mult Scler Houndmills Basingstoke Engl, vol.18, pp.1721-1757, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00826751
T-cell regulation by CD46 and its relevance in multiple sclerosis, Immunology, vol.124, pp.149-54, 2008. ,
URL : https://hal.archives-ouvertes.fr/hal-02322284
Complement as a regulator of adaptive immunity, Semin Immunopathol, vol.40, pp.37-48, 2017. ,
URL : https://hal.archives-ouvertes.fr/inserm-01593213
Développement d'un Modèle Murin Transgénique D'infection par L'herpèsvirus 6A et étude des Mécanismes D'induction de la Neuroinflammation, 2013. ,