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, Right panel: Results are 740 expressed as specific median fluorescence intensity (MFI) (mean ± SD, p.741
Tumor cell surface phenotyping was 743 performed by flow cytometry using specific antibodies against ULBP 1, ULBP 2/5/6, ULBP 3 744 and MIC A/B expression. Histograms correspond to, respectively, CNP and MES GBM 745 cultures as in (B). Results are expressed as specific median fluorescence intensity (MFI) 746 (mean ± SD ,
, Allogeneic human V?9V?2 T lymphocytes efficiently eliminate primary 749 mesenchymal GBM cells in vivo
, Allogeneic 752 human V?9V?2 T lymphocytes were injected at the tumor site at days 7, 14 and 21 after 753 tumor cell implantation. Bottom panel Relative number of subjects at risk for each group and 754 median survival of GBM-1 tumor-bearing mice treated with V?9V?2 T lymphocytes are 755 indicated in the table, Mice treated with highly reactive V?9V?2 T lymphocytes were divided 756 in poor and good responders (R) (n=15 mice treated with poorly or highly reactive V?9V?2 T 757 lymphocytes, n=8 for poor responders and n=7 for good responders; Log-rank Test
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