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Droplet-Based Microfluidics Digital PCR for the Detection of KRAS Mutations

Deniz Pekin 1 Valérie Taly 2, *
* Corresponding author
1 CRPP - Centre de Recherche Paul Pascal
2 MEPPOT - U1147 - Médecine Personnalisée, Pharmacogénomique, Optimisation Thérapeutique
Abstract : We demonstrate an accurate and sensitive quantification of mutated KRAS oncogene in genomic DNA, using droplet-based microfluidics and digital PCR.
Keywords : Biomarkers Cancer Digital PCR Droplet microfluidics KRAS
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Journal articles
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https://www.hal.inserm.fr/inserm-02299534
Contributor : Valerie Taly <>
Submitted on : Friday, September 27, 2019 - 6:06:59 PM
Last modification on : Friday, March 27, 2020 - 2:36:52 AM

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CNRS | UNIV-PARIS5 | USPC | UNIV-PARIS

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Deniz Pekin, Valérie Taly. Droplet-Based Microfluidics Digital PCR for the Detection of KRAS Mutations. Methods in Molecular Biology, Humana Press/Springer Imprint, 2017, 1547, pp.143-164. ⟨10.1007/978-1-4939-6734-6_12⟩. ⟨inserm-02299534⟩

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