Coins in microfluidics: From mere scale objects to font of inspiration for microchannel circuits

Abstract : The fabrication of microfluidic chips remains a complex and expensive process requiring specific equipment and protocols, often if not always limited to the most privileged laboratories. As an alternative to the most sophisticated methods, the present paper describes the fabrication of microfluidic chips by an approach that uses coins as positive master for the rapid production of multigeometry chips. All steps of chip production were carried out using inexpensive approaches by low-cost chemicals and equipment. The chips were validated by different "classic" microfluidic tasks, such as hydrodynamic focusing, droplets generation, micromixing, and on-chip cell culture. The use of coins is not only an efficient method for rapid prototyping but also represents an inspiring possibility for the design of new microfluidic chips. Finally, coin-inspired chips could represent a laboratory experiment doable at a high school level.
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Journal articles
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https://www.hal.inserm.fr/inserm-02299485
Contributor : Valerie Taly <>
Submitted on : Friday, September 27, 2019 - 5:36:30 PM
Last modification on : Wednesday, October 2, 2019 - 1:14:41 AM

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Gabriele Pitingolo, Valérie Taly, Claudio Nastruzzi. Coins in microfluidics: From mere scale objects to font of inspiration for microchannel circuits. Biomicrofluidics, American Institute of Physics, 2019, 13 (2), pp.024106. ⟨10.1063/1.5086535⟩. ⟨inserm-02299485⟩

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