L. Tautz, D. A. Critton, and S. Grotegut, Protein tyrosine phosphatases: structure, function, and implication in human disease, Methods Mol. Biol, vol.1053, pp.179-221, 2013.

N. K. Tonkss, C. D. Diltz, and E. H. Fischer, Purification of the major protein-tyrosine-phosphatases of human placenta, J. Biol. Chem, vol.263, pp.6722-6730, 1988.

N. K. Tonks, C. D. Diltz, and E. H. Fischer, Characterization of the major protein-tyrosinephosphatases of human placenta, J. Biol. Chem, vol.263, pp.6731-6737, 1988.

P. S. Tappia, R. P. Sharma, and G. J. Sale, Dephosphorylation of autophosphorylated insulin and epidermal-growth-factor receptors by two major subtypes of protein-tyrosinephosphatase from human placenta, Biochem. J, vol.278, pp.69-74, 1991.

N. Hashimoto, W. R. Zhang, and B. J. Goldstein, Insulin receptor and epidermal growth factor receptor dephosphorylation by three major rat liver protein-tyrosine phosphatases expressed in a recombinant bacterial system, Biochem. J, vol.284, pp.569-576, 1992.

F. Ahmad, P. M. Li, J. Meyerovitch, and B. J. Goldstein, Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway, J. Biol. Chem, vol.270, pp.20503-20508, 1995.

A. Cheng, N. Uetani, P. D. Simoncic, V. P. Chaubey, A. Lee-loy et al., Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B, Dev. Cell, vol.2, pp.497-503, 2002.

M. Elchebly, P. Payette, E. Michaliszyn, W. Cromlish, S. Collins et al., Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene, Science, vol.283, pp.1544-1548, 1999.

L. D. Klaman, O. Boss, O. D. Peroni, J. K. Kim, J. L. Martino et al., Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice, Mol. Cell. Biol, vol.20, pp.5479-5489, 2000.

K. K. Bence, M. Delibegovic, B. Xue, C. Z. Gorgun, G. S. Hotamisligil et al., Neuronal PTP1B regulates body weight, adiposity and leptin action, Nat. Med, vol.12, pp.917-924, 2006.

J. V. Frangioni, P. H. Beahm, C. A. Jost, and B. G. Neel, The nontransmembrane tyrosine phosphatase PTP-1 B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence, Cell, vol.68, pp.545-560, 1992.

I. Anderie, I. Schulz, and A. Schmid, Characterization of the C-terminal ER membrane anchor of PTP1B, Exp. Cell Res, vol.313, pp.3189-3197, 2007.

J. Bakke and F. G. Haj, Protein-tyrosine phosphatase 1B substrates and metabolic regulation, Semin. Cell Dev. Biol, vol.37, pp.58-65, 2015.

N. Boute, S. Boubekeur, D. Lacasa, and T. Issad, Dynamics of the interaction between the insulin receptor and protein tyrosine-phosphatase 1B in living cells, EMBO Rep, vol.4, pp.313-319, 2003.

F. G. Haj, P. J. Verveer, A. Squire, B. G. Neel, and P. I. Bastiaens, Imaging Sites of Receptor Dephosphorylation by PTP1B on the Surface of the Endoplasmic Reticulum, vol.295, pp.1708-1712, 2002.

Y. Romsicki, M. Reece, J. Gauthier, E. Asante-appiah, and B. P. Kennedy, Protein tyrosine phosphatase-1B dephosphorylation of the insulin receptor occurs in a Perinuclear endosome compartment in human embryonic kidney 293 cells, J. Biol. Chem, vol.279, pp.12868-12875, 2004.

W. A. Cromlish, M. Tang, R. Kyskan, L. Tran, and B. P. Kennedy, PTP1B-dependent insulin receptor phosphorylation/residency in the endocytic recycling compartment of CHO-IR cells, Biochem. Pharmacol, vol.72, pp.1279-1292, 2006.

M. Stuible, J. V. Abella, M. Feldhammer, M. Nossov, V. Sangwan et al., PTP1B targets the endosomal sorting machinery dephosphorylation of regulatory sites on the endosomal sorting complex, J. Biol. Chem, vol.285, pp.23899-23907, 2010.

M. Stuible and M. L. Tremblay, In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis, Trends Cell Biol, vol.20, pp.672-679, 2010.

F. Gu, T. N. Duc, M. Stuible, N. Dubé, M. L. Tremblay et al., Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress, J. Biol. Chem, vol.279, pp.49689-49693, 2004.

M. Delibegovic, D. Zimmer, C. Kauffman, K. Rak, E. Hong et al., Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress, Diabetes, vol.58, pp.590-599, 2009.

A. Bettaieb, S. Liu, Y. Xi, N. Nagata, K. Matsuo et al., Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphatase, J. Biol. Chem, vol.286, pp.9225-9235, 2011.

N. Krishnan, C. Fu, D. J. Pappin, and N. K. Tonks, H2S-induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response, Sci. Signal, vol.4, pp.1-12, 2011.

A. Bettaieb, K. Matsuo, I. Matsuo, S. Wang, R. Melhem et al., Protein tyrosine phosphatase 1B deficiency potentiates PERK/eiF2? signaling in brown adipocytes, PLoS One, vol.7, pp.1-10, 2012.

C. Owen, E. K. Lees, L. Grant, D. J. Zimmer, N. Mody et al., Inducible liverspecific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice, Diabetologia, vol.56, pp.2286-2296, 2013.

E. Panzhinskiy, Y. Hua, B. Culver, J. Ren, and S. Nair, Endoplasmic reticulum stress upregulates protein tyrosine phosphatase 1B and impairs glucose uptake in cultured myotubes, Diabetologia, vol.56, pp.598-607, 2013.

A. Arachiche, O. Augereau, M. Decossas, C. Pertuiset, E. Gontier et al., Localization of PTP-1B, SHP-2, and Src exclusively in rat brain mitochondria and functional consequences, J. Biol. Chem, vol.283, pp.24406-24411, 2008.

J. Fueller, M. V. Egorov, K. A. Walther, O. Sabet, J. Mallah et al., Subcellular partitioning of protein tyrosine phosphatase 1B to the endoplasmic reticulum and mitochondria depends sensitively on the composition of its tail anchor, PLoS One, vol.10, pp.1-31, 2015.

H. Ruan, N. Hacohen, T. R. Golub, L. Van-parijs, and H. F. Lodish, Tumor necrosis factor-? suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes, Diabetes, vol.51, pp.1319-1336, 2002.

J. M. Zabolotny, Y. Kim, L. A. Welsh, E. E. Kershaw, B. G. Neel et al., Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo, J. Biol. Chem, vol.283, pp.14230-14241, 2008.

R. Ide, H. Maegawa, R. Kikkawa, Y. Shigeta, and A. Kashiwagi, High glucose condition activates protein tyrosine phosphatases and deactivates insulin receptor function in insulin-sensitive rat fibroblasts, Biochem. Biophys. Res. Commun, vol.201, pp.71-77, 1994.

S. Inada, Y. Ikeda, T. Suehiro, H. Takata, F. Osaki et al., Glucose enhances protein tyrosine phosphatase 1B gene transcription in hepatocytes, Mol. Cell. Endocrinol, vol.271, pp.64-70, 2007.

B. A. Zinker, C. M. Rondinone, J. M. Trevillyan, R. J. Gum, J. E. Clampit et al., PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose , and improves insulin sensitivity in diabetic mice, Proc. Natl. Acad. Sci. U. S. A, vol.99, pp.11357-11362, 2002.

M. Feldhammer, N. Uetani, D. Miranda-saavedra, and L. Michel, PTP1B: a simple enzyme for a complex world, Crit. Rev. Biochem. Mol. Biol, vol.48, pp.430-445, 2013.

T. Fukada and N. K. Tonks, Identification of YB-1 as a regulator of PTP1B expression: implications for regulation of insulin and cytokine signaling, EMBO J, vol.22, pp.479-493, 2003.

L. Lessard, D. P. Labbé, G. Deblois, F. Saad, L. C. Trotman et al., PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer, Cancer Res, vol.72, pp.1529-1538, 2012.

S. Hu, M. Huang, Z. Li, F. Jia, Z. Ghosh et al., MicroRNA-210 as a novel therapy for treatment of ischemic heart disease, Circulation, vol.122, pp.124-131, 2010.

Y. M. Yang, S. Y. Seo, T. H. Kim, and S. G. Kim, Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid, Hepatology, vol.56, pp.2209-2220, 2012.

S. Yip, S. Saha, and J. Chernoff, PTP1B: a double agent in metabolism and oncogenesis, Trends Biochem. Sci, vol.35, pp.442-449, 2010.

K. Takakura, J. S. Beckman, L. A. Macmillan-crow, and J. P. Crow, Rapid and irreversible inactivation of protein tyrosine, Arch. Biochem. Biophys, vol.369, pp.197-207, 1999.

Y. R. Hadari, B. Geiger, O. Nadiv, I. Sabanay, C. T. Roberts et al., Hepatic tyrosine-phosphorylated proteins identified and localized following in vivo inhibition of protein tyrosine phosphatases: effects of H2O2 and vanadate administration into rat livers, Mol. Cell. Endocrinol, vol.97, pp.9-17, 1993.

S. G. Sullivan, M. Jamin, and A. Stern, Effects of H2O2 on protein tyrosine phosphatase activity in HER14 cells, Free Radic, Biol. Med, vol.16, pp.399-403, 1994.

B. J. Goldstein, K. Mahadev, M. Kalyankar, and X. Wu, Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets, Diabetes, vol.54, pp.311-321, 2005.

Y. Chen, H. Chu, K. Pan, C. Teng, D. Wang et al., Cysteine S -Nitrosylation Protects Protein-tyrosine Phosphatase 1B Against Oxidation-induced, vol.283, pp.35265-35272, 2008.

Y. Lou, Y. Chen, S. Hsu, R. Chen, C. Lee et al., Redox Regulation of the Protein Tyrosine Phosphatase PTP1B in Cancer Cells, vol.275, pp.69-88, 2008.

H. Wang, A. X. Wang, K. Aylor, and E. J. Barrett, Nitric oxide directly promotes vascular endothelial insulin transport, Diabetes, vol.62, pp.4030-4042, 2013.

L. V. Ravichandran, H. Chen, Y. Li, and M. J. Quon, Phosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor, Mol. Endocrinol, vol.15, pp.1768-1780, 2001.

W. Chen, D. L. Harris, and N. C. Joyce, Effects of SOV-induced phosphatase inhibition and expression of protein tyrosine phosphatases in rat corneal endothelial cells, Exp. Eye Res, vol.81, pp.570-580, 2005.

M. Vercauteren, E. Remy, C. Devaux, B. Dautreaux, J. P. Henry et al., Improvement of peripheral endothelial dysfunction by protein tyrosine phosphatase inhibitors in heart failure, Circulation, vol.114, pp.2498-2507, 2006.

Y. Nakamura, N. Patrushev, H. Inomata, D. Mehta, N. Urao et al., Role of protein tyrosine phosphatase 1B in vascular endothelial growth factor signaling and cell-cell adhesions in endothelial cells, Circ. Res, vol.102, pp.1182-1191, 2008.

A. A. Lanahan, D. Lech, A. Dubrac, J. Zhang, Z. W. Zhuang et al., PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells, Circulation, vol.130, pp.902-909, 2014.

M. Besnier, A. Galaup, L. Nicol, J. Henry, D. Coquerel et al., Enhanced angiogenesis and increased cardiac perfusion after myocardial infarction in protein tyrosine phosphatase 1B-deficient mice, FASEB, vol.28, pp.3351-3361, 2014.
URL : https://hal.archives-ouvertes.fr/hal-02142777

M. Potente, H. Gerhardt, and P. Carmeliet, Basic and therapeutic aspects of angiogenesis, Cell, vol.146, pp.873-887, 2011.

J. Zhang, L. Li, J. Li, Y. Liu, C. Zhang et al., Protein tyrosine phosphatase 1B impairs diabetic wound healing through vascular endothelial growth factor receptor 2 dephosphorylation, Arterioscler. Thromb. Vasc. Biol, vol.35, pp.163-174, 2015.

E. Tzima, M. Irani-tehrani, W. B. Kiosses, E. Dejana, D. A. Schultz et al., A mechanosensory complex that mediates the endothelial cell response to fluid shear stress, Nature, vol.437, pp.426-431, 2005.

Y. Chang, B. Ceacareanu, D. Zhuang, C. Zhang, Q. Pu et al., Counterregulatory function of protein tyrosine phosphatase 1B in platelet-derived growth factor-or fibroblast growth factor-induced motility and proliferation of cultured smooth muscle cells and in neointima formation, Arterioscler. Thromb. Vasc. Biol, vol.26, pp.501-507, 2006.

B. Markova, P. Herrlich, L. Rönnstrand, and F. Böhmer, Identification of protein tyrosine phosphatases associating with the PDGF receptor, Biochemistry, vol.42, pp.2691-2699, 2003.

A. Hassid, S. Huang, and J. Yao, Role of PTP-1B in aortic smooth muscle cell motility and tyrosine phosphorylation of focal adhesion proteins, Am. J. Phys, vol.277, pp.192-198, 1999.

F. Liu, D. E. Hill, and J. Chernoff, Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas), J. Biol. Chem, vol.271, pp.31290-31295, 1996.

M. B. Wright, R. A. Seifert, and D. F. Bowen-pope, Protein-tyrosine phosphatases in the Vessel Wall differential expression after acute arterial injury, Arterioscler. Thromb. Vasc. Biol, vol.20, pp.1189-1198, 2000.

D. Zhuang, Q. Pu, B. Ceacareanu, Y. Chang, M. Dixit et al., Chronic insulin treatment amplifies PDGF-induced motility in differentiated aortic smooth muscle cells by suppressing the expression and function of PTP1B, Am. J. Physiol. Heart Circ. Physiol, vol.295, pp.163-173, 2008.

H. Song, Z. Zhang, and L. Wang, Small interference RNA against PTP-1B reduces hypoxia/ reoxygenation induced apoptosis of rat cardiomyocytes, Apoptosis, vol.13, pp.383-393, 2008.

C. X. Fang, T. A. Doser, X. Yang, N. Sreejayan, and J. Ren, Metallothionein antagonizes aging-induced cardiac contractile dysfunction: role of PTP1B, insulin receptor tyrosine phosphorylation and Akt, Aging Cell, vol.5, pp.177-185, 2006.

M. R. Kandadi, E. Panzhinskiy, N. D. Roe, S. Nair, D. Hu et al., Biochimica et Biophysica Acta deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: role of AMPK-dependent autophagy, Biochim. Biophys. Acta (BBA) -Mol, pp.299-309

F. Dong, C. X. Fang, X. Yang, X. Zhang, F. L. Lopez et al., Cardiac overexpression of catalase rescues cardiac contractile dysfunction induced by insulin resistance: role of oxidative stress , protein carbonyl formation and insulin sensitivity, Diabetologia, vol.49, pp.1421-1433, 2006.

P. Zhou and W. T. Pu, Recounting cardiac cellular composition, Circ. Res, vol.118, pp.368-370, 2016.

E. Gomez, M. Vercauteren, B. Kurtz, A. Ouvrard-pascaud, P. Mulder et al., Reduction of heart failure by pharmacological inhibition or gene deletion of protein tyrosine phosphatase 1B, J. Mol. Cell. Cardiol, vol.52, pp.1257-1264, 2012.
URL : https://hal.archives-ouvertes.fr/inserm-00801304

J. Maupoint, M. Besnier, E. Gomez, N. Bouhzam, J. P. Henry et al., Selective vascular endothelial protection reduces cardiac dysfunction in chronic heart failure, Circ. Heart Fail, vol.9, p.2895, 2016.
URL : https://hal.archives-ouvertes.fr/inserm-02296623

R. Gogiraju, M. R. Schroeter, M. L. Bochenek, A. Hubert, T. Münzel et al., Endothelial deletion of protein tyrosine phosphatase-1B protects against pressure overload-induced heart failure in mice, Cardiovasc. Res, vol.111, pp.204-216, 2016.

C. S. Deutschman and K. J. Tracey, Sepsis: current dogma and new perspectives, Immunity, vol.40, pp.463-475, 2014.

D. D. Backer, D. Cortes, K. Donadello, and J. Vincent, Pathophysiology of microcirculatory dysfunction and the pathogenesis of septic shock, Virulence, vol.5, pp.73-79, 2014.

E. G. King, G. J. Bauzá, J. R. Mella, and D. G. Remick, Pathophysiologic mechanisms in septic shock, Lab. Investig, vol.94, pp.4-12, 2014.

H. Ait-oufella, E. Maury, S. Lehoux, B. Guidet, and G. Offenstadt, The endothelium: physiological functions and role in microcirculatory failure during severe sepsis, Intensive Care Med, vol.36, pp.1286-1298, 2010.

H. Xu, H. An, J. Hou, C. Han, P. Wang et al., Phosphatase PTP1B Negatively Regulates MyD88-and TRIF-dependent Proinflammatory Cytokine and Type I Interferon Production in TLR-triggered Macrophages, vol.45, pp.3545-3552, 2008.

K. L. Grinnell, H. Chichger, J. Braza, H. Duong, and E. O. Harrington, Protection against LPSinduced pulmonary edema through the attenuation of protein tyrosine phosphatase -1B oxidation, Am. J. Respir. Cell Mol. Biol, vol.46, pp.623-632, 2012.

K. Chen, M. T. Kirber, H. Xiao, Y. Yang, and J. F. , Regulation of ROS signal transduction by NADPH oxidase 4 localization, J. Cell Biol, vol.181, pp.1129-1139, 2008.

D. Coquerel, R. Neviere, E. Delile, P. Mulder, X. Marechal et al., Gene deletion of protein tyrosine phosphatase 1B protects against sepsis-induced cardiovascular dysfunction and mortality, Arterioscler. Thromb. Vasc. Biol, vol.34, pp.1032-1044, 2014.

M. C. Mcguire, R. M. Fields, B. L. Nyomba, I. Raz, C. Bogardus et al., Abnormal regulation of protein tyrosine phosphatase activities in skeletal muscle of insulin-resistant humans, Diabetes, vol.40, pp.939-942, 1991.

F. Ahmad and B. J. Goldstein, Increased abundance of specific skeletal muscle PTP in a genetic model of insulin-resistant obesity and diabetes mellitus, Metabolism, vol.9, pp.1175-1184, 1995.

M. Delibegovic, K. K. Bence, N. Mody, E. Hong, H. J. Ko et al., Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B, Mol. Cell. Biol, vol.27, pp.7727-7734, 2007.

M. Laakso and J. Kuusisto, Insulin resistance and hyperglycaemia in cardiovascular disease development, Nat. Publ. Group, vol.10, pp.293-302, 2014.

F. Paneni, S. Costantino, and F. Cosentino, Insulin resistance, diabetes, and cardiovascular risk, Curr. Atheroscler. Rep, vol.16, pp.1-8, 2014.

S. Turco, M. Gaggini, G. Daniele, G. Basta, F. Folli et al., Insulin resistance and endothelial dysfunction: a mutual relationship in cardiometabolic risk, Curr. Pharm. Des, vol.19, pp.2420-2431, 2013.

R. Muniyappa and J. R. Sowers, Role of insulin resistance in endothelial dysfunction, Rev. Endocr. Metab. Disord, vol.14, pp.5-12, 2013.

M. I. Ali, P. Ketsawatsomkron, E. J. De-chantemele, J. D. Mintz, K. Muta et al., Deletion of protein tyrosine phosphatase 1b improves peripheral insulin resistance and vascular function in obese, leptin-resistant mice via reduced oxidant tone, Circ. Res, vol.105, pp.1013-1022, 2009.

S. Nemoto, T. Matsumoto, K. Taguchi, and T. Kobayashi, Relationships among protein tyrosine phosphatase 1B, angiotensin II, and insulin-mediated aortic responses in type 2 diabetic Goto e Kakizaki rats, Atherosclerosis, vol.233, pp.64-71, 2014.

D. J. Herre, J. B. Norman, R. Anderson, and M. L. Tremblay, Deletion of protein tyrosine phosphatase 1B ( PTP1B ) enhances endothelial cyclooxygenase 2 expression and protects mice from type 1 diabetes-induced endothelial dysfunction, PLoS One, vol.10, 2015.

Z. Zhang, Protein tyrosine phosphatases: structure and function, substrate specificity, and inhibitor development, Annu. Rev. Pharmacol. Toxicol, vol.42, pp.209-234, 2002.

S. Zhang and Z. Zhang, PTP1B as a drug target: recent developments in PTP1B inhibitor discovery, vol.12, pp.373-381, 2007.

R. He, L. Zeng, Y. He, S. Zhang, and Z. Zhang, Small Molecule Tools for Functional Interrogation of Protein Tyrosine Phosphatases, vol.280, pp.731-750, 2013.

C. Wiesmann, K. J. Barr, J. Kung, J. Zhu, D. A. Erlanson et al., Allosteric inhibition of protein tyrosine phosphatase 1B, Nat. Struct. Mol. Biol, vol.11, pp.730-737, 2004.

N. Krishnan, D. Koveal, D. H. Miller, B. Xue, S. D. Akshinthala et al., Targeting the Disordered C Terminus of PTP1B With an Allosteric Inhibitor, vol.10, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01131138

K. A. Lantz, S. G. Hart, S. L. Planey, M. F. Roitman, I. A. Ruiz-white et al., Inhibition of PTP1B by trodusquemine (MSI-1436) causes fat-specific weight loss in diet-induced obese mice, Obesity, vol.18, pp.1516-1523, 2009.

Z. Qin, N. R. Pandey, X. Zhou, C. A. Stewart, A. Hari et al., Functional properties of claramine: a novel PTP1B inhibitor and insulin-mimetic compound, Biochem. Biophys. Res. Commun, vol.458, pp.21-27, 2015.

C. M. Rondinone, J. M. Trevillyan, J. Clampit, R. J. Gum, C. Berg et al., Protein tyrosine phosphatase 1B reduction regulates adiposity and expression of genes involved in lipogenesis, Diabetes, vol.51, pp.2405-2411, 2002.

M. M. Swarbrick, P. J. Havel, A. A. Levin, A. A. Bremer, K. L. Stanhope et al., Inhibition of protein tyrosine phosphatase-1B with in monkeys, Endocrinology, vol.150, pp.1670-1679, 2009.

S. P. Henry, M. Johnson, T. A. Zanardi, R. Fey, D. Auyeung et al., Renal uptake and tolerability of a 2-O-methoxyethyl modified antisense oligonucleotide (ISIS 113715) in monkey, Toxicology, vol.301, pp.13-20, 2012.