D. C. Angus, P. Pereira, C. A. Silva, and E. , Epidemiology of severe sepsis around the world, Endocr Metab Immune Disord Drug Targets, vol.6, issue.2, pp.207-212, 2006.

L. Li and J. L. Messina, Acute insulin resistance following injury, Trends Endocrinol Metab, vol.20, issue.9, pp.429-435, 2009.

A. El-osta, D. Brasacchio, D. Yao, A. Pocai, P. L. Jones et al., Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia, J Exp Med, vol.205, issue.10, pp.2409-2417, 2008.

D. Vlasselaers, D. Mesotten, L. Langouche, I. Vanhorebeek, I. Van-den-heuvel et al., Tight glycemic control protects the myocardium and reduces inflammation in neonatal heart surgery, Ann Thorac Surg, vol.90, issue.1, pp.22-29, 2010.

G. Van-den-berghe, P. Wouters, F. Weekers, C. Verwaest, F. Bruyninckx et al., Intensive insulin therapy in critically ill patients, N Engl J Med, vol.345, pp.1359-1367, 2001.

M. G. Jeschke, D. Klein, and D. N. Herndon, Insulin treatment improves the systemic inflammatory reaction to severe trauma, Ann Surg, vol.239, issue.4, pp.553-560, 2004.

S. Hagiwara, H. Iwasaka, A. Hasegawa, N. Asai, and T. Noguchi, Hyperglycemia contributes to cardiac dysfunction in a lipopolysaccharide-induced systemic inflammation model, Crit Care Med, vol.37, issue.7, pp.2223-2227, 2009.

D. B. Savage, K. F. Petersen, and G. I. Shulman, Mechanisms of insulin resistance in humans and possible links with inflammation, Hypertension, vol.45, issue.5, pp.828-833, 2005.

P. R. Shepherd and B. B. Kahn, Glucose transporters and insulin action-implications for insulin resistance and diabetes mellitus, N Engl J Med, vol.341, issue.4, pp.248-257, 1999.

L. H. Thompson, H. T. Kim, Y. Ma, N. A. Kokorina, and J. L. Messina, Acute muscle-type specific insulin resistance following injury, Mol Med, vol.14, pp.715-723, 2008.

J. C. Orban, D. Deroche, and C. Ichai, Septic shock: blood glucose regulation, Ann Fr Anesth Reanim, vol.25, issue.3, pp.275-279, 2006.

R. L. Gamelli, H. Liu, L. K. He, and C. A. Hofmann, Alterations of glucose transporter mRNA and protein levels in brain following thermal injury and sepsis in mice, Shock, vol.1, issue.6, pp.395-400, 1994.

M. Elchebly, P. Payette, E. Michaliszyn, W. Cromlish, S. Collins et al., Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene, Science, vol.283, issue.5407, pp.1544-1548, 1999.

M. Vercauteren, R. E. Devaux, C. Dautreaux, B. Henry, J. P. Bauer et al., Improvement of peripheral endothelial dysfunction by protein tyrosine phosphatase inhibitors in heart failure, Circulation, vol.114, issue.23, pp.2498-2507, 2006.

J. Maupoint, M. Besnier, E. Gomez, N. Bouhzam, J. P. Henry et al., Selective vascular endothelial protection reduces cardiac dysfunction in chronic heart failure, Circ Heart Fail, vol.9, issue.4, p.2895, 2016.
URL : https://hal.archives-ouvertes.fr/inserm-02296623

P. A. Thiebaut, M. Besnier, E. Gomez, and V. Richard, Role of protein tyrosine phosphatase 1B in cardiovascular diseases, J Mol Cell Cardiol, vol.101, pp.50-57, 2016.
URL : https://hal.archives-ouvertes.fr/inserm-02296621

D. Coquerel, R. Neviere, E. Delile, P. Mulder, X. Marechal et al., Gene deletion of protein tyrosine phosphatase 1B protects against sepsis-induced cardiovascular dysfunction and mortality, Arterioscler Thromb Vasc Biol, vol.34, issue.5, pp.1032-1044, 2014.
URL : https://hal.archives-ouvertes.fr/inserm-02296639

C. F. Raetzsch, N. L. Brooks, J. M. Alderman, K. S. Moore, P. A. Hosick et al., Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappa b pathway, Hepatology, vol.50, issue.2, pp.592-600, 2009.

J. G. Heuer, D. L. Bailey, G. R. Sharma, T. Zhang, C. Ding et al., Cecal ligation and puncture with total parenteral nutrition: a clinically relevant model of the metabolic, hormonal, and inflammatory dysfunction associated with critical illness, J Surg Res, vol.121, issue.2, pp.178-186, 2004.

L. Dejager, I. Pinheiro, E. Dejonckheere, and C. Libert, Cecal ligation and puncture: the gold standard model for polymicrobial sepsis?, Trends Microbiol, vol.19, issue.4, pp.198-208, 2011.

W. Fuller, P. Eaton, R. A. Medina, J. Bell, and M. J. Shattock, Differential centrifugation separates cardiac sarcolemmal and endosomal membranes from Langendorffperfused rat hearts, Anal Biochem, vol.293, issue.2, pp.216-223, 2001.

J. J. Luiken, D. P. Koonen, J. Willems, A. Zorzano, C. Becker et al., Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36, Diabetes, vol.51, issue.10, pp.3113-3119, 2002.

S. Brierre, R. Kumari, and B. P. Deboisblanc, The endocrine system during sepsis, Am J Med Sci, vol.328, issue.4, pp.238-247, 2004.

R. T. Watson and J. E. Pessin, GLUT-4 translocation: the last 200 nanometers, Cell Signal, vol.19, issue.11, pp.2209-2217, 2007.

S. S. Bae, H. Cho, J. Mu, and M. J. Birnbaum, Isoform-specific regulation of insulindependent glucose uptake by Akt/protein kinase B, J Biol Chem, vol.278, issue.49, pp.49530-49536, 2003.

N. Matsuda, S. Yamamoto, H. Yokoo, K. Tobe, and Y. Hattori, Nuclear factor-kappaB decoy oligodeoxynucleotides ameliorate impaired glucose tolerance and insulin resistance in mice with cecal ligation and puncture-induced sepsis, Crit Care Med, vol.37, issue.10, pp.2791-2799, 2009.

J. A. Engelman, J. Luo, and L. C. Cantley, The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism, Nat Rev Genet, vol.7, issue.8, pp.606-619, 2006.

A. Sriwijitkamol, D. K. Coletta, E. Wajcberg, G. B. Balbontin, S. M. Reyna et al., Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study, Diabetes, vol.56, issue.3, pp.836-848, 2007.

E. A. Richter and M. Hargreaves, Exercise, GLUT-4, and skeletal muscle glucose uptake, Physiol Rev, vol.93, issue.3, pp.993-1017, 2013.

M. R. Kandadi, E. Panzhinskiy, N. D. Roe, S. Nair, D. Hu et al., Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat dietinduced obesity: role of AMPK-dependent autophagy, Biochim Biophys Acta, vol.1852, issue.2, pp.299-309, 2015.

B. Xue, T. Pulinilkunnil, I. Murano, K. K. Bence, H. He et al., Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues, Mol Cell Biol, vol.29, issue.16, pp.4563-4573, 2009.

V. Rotter, I. Nagaev, and U. Smith, Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects, J Biol Chem, vol.278, pp.45777-45784, 2003.

R. Y. Su, Y. Chao, T. Y. Chen, D. Y. Huang, and W. W. Lin, 5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL-and TNFa-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling, Mol Cancer Ther, vol.6, issue.5, pp.1562-1571, 2007.

P. J. Randle, P. B. Garland, C. N. Hales, and E. A. Newsholme, The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus, Lancet, vol.1, issue.7285, pp.785-789, 1963.

P. Schrauwen, S. Timmers, and M. K. Hesselink, Blocking the entrance to open the gate, Diabetes, vol.62, issue.3, pp.703-705, 2013.

H. O. Steinberg, H. Chaker, R. Leaming, A. Johnson, G. Brechtel et al., Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance, J Clin Invest, vol.97, issue.11, pp.2601-2610, 1996.

D. Roy, M. Perreault, and A. Marette, Insulin stimulation of glucose uptake in skeletal muscles and adipose tissues in vivo is NO dependent, Am J Physiol, vol.274, pp.692-699, 1998.

H. Duplain, R. Burcelin, C. Sartori, S. Cook, M. Egli et al., Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase, Circulation, vol.104, issue.3, pp.342-345, 2001.

S. Cook, O. Hugli, M. Egli, B. Ménard, S. Thalmann et al., Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension, Diabetes, vol.53, issue.8, pp.2067-2072, 2004.