, Ovarian cancer multi-omics data visualisation on ACSN: zoomed on WNT non-canonical signalling pathway. Immunoreactive (A) and Proliferative (B) subtypes are compared. Patches using the map staining function represent the average expression level of the corresponding genes, vol.14
, Abbreviations ACSN: Atlas of Cancer Signalling Network; ATP: Adenosine triphosphate
, GMT: Gene Matrix Transposed file format; HGNC: HUGO Gene Nomenclature Committee; HTML: HyperText Markup Language; HTTP: HyperText Transfer Protocol; HUGO: Human Genome Organization; SBGN: Systems Biology Graphical Notation; SBML: Systems Biology Markup Language; TCGA: The Cancer Genome Atlas
ReconMap: an interactive visualization of human metabolism, Bioinformatics, vol.33, issue.4, pp.605-612, 2017. ,
A community-driven global reconstruction of human metabolism, Nat Biotechnol, vol.31, issue.5, pp.419-444, 2013. ,
Atlas of Cancer Signalling network: a systems biology resource for integrative analysis of cancer data with Google maps, Oncogenesis, vol.4, 2015. ,
NaviCell: a web-based environment for navigation, curation and maintenance of large molecular interaction maps, BMC Syst Biol, vol.7, 2013. ,
URL : https://hal.archives-ouvertes.fr/inserm-00872428
NaviCell web service for network-based data visualization, Nucleic Acids Res, vol.43, issue.W1, pp.560-565, 2015. ,
Using process diagrams for the graphical representation of biological networks, Nat Biotechnol, 2005. ,
Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis, Nucleic Acids Res, vol.41, pp.8853-71, 2013. ,
Independent component analysis uncovers the landscape of the bladder tumor transcriptome and reveals insights into luminal and basal subtypes, Cell Rep, vol.9, issue.4, pp.1235-1280, 2014. ,
Drugdriven synthetic lethality: bypassing tumor cell genetics with a combination of AsiDNA and PARP inhibitors, Clin Cancer Res, vol.23, issue.4, pp.1001-1012, 2017. ,
CellDesigner: a process diagram editor for gene-regulatory and biochemical networks, BIOSILICO, vol.1, issue.5, pp.159-62, 2003. ,
CellDesigner 3.5: a versatile modeling tool for biochemical networks, Proc IEEE, vol.96, issue.8, pp.1254-65, 2008. ,
BiNoM: a Cytoscape plugin for manipulating and analyzing biological networks, Bioinformatics, vol.24, issue.6, pp.876-883, 2008. ,
BiNoM 2.0, a Cytoscape plugin for accessing and analyzing pathways using standard systems biology formats, BMC Syst Biol, vol.7, 2013. ,
URL : https://hal.archives-ouvertes.fr/inserm-00820930
, Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma, Nature, vol.474, issue.7353, pp.609-624, 2011.
Defining the role of the Bcl-2 family proteins in Huntington's disease, Cell Death Dis, vol.4, issue.8, p.772, 2013. ,
Mitochondria and apoptosis, Science, vol.281, issue.5381, pp.1309-1321, 1998. ,
The role of mitochondria in apoptosis, Annu Rev Genet, vol.43, pp.95-118, 2009. ,
Phosphoinositide metabolism and Ca2+ oscillation, Biochemistry, vol.63, issue.1, pp.38-46, 1998. ,
Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer, Sci Rep, vol.5, issue.1, p.8473, 2015. ,
Amino acid deprivation induces both apoptosis and autophagy in murine C2C12 muscle cells, Biotechnol Lett, vol.27, issue.16, pp.1157-63, 2005. ,
Selective amino acid restriction differentially affects the motility and directionality of DU145 and PC3 prostate cancer cells, J Cell Physiol, vol.217, issue.1, pp.184-93, 2008. ,
Uptake of amino acids and thymidine during the first cell cycle of synchronized hamster cells, J Membrane Biol, vol.26, pp.1-17, 1976. ,
Amino acid signalling and the integration of metabolism, Biochem Biophys Res Commun, vol.313, pp.397-403, 2004. ,
Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer, EMBO J, 2014. ,
Representation and quantification of module activity from target expression data, Front Genet, vol.7, p.18, 2016. ,
Quantitative prediction of cellular metabolism with constraint-based models: the COBRA toolbox v2.0, Nat Protoc, vol.6, issue.9, pp.1290-307, 2011. ,