Survival and specific outcome of sickle cell disease patients after renal transplantation

Abstract : The prognosis of sickle cell disease (SCD) patients who need dialysis is poor, but experience with kidney transplantation is limited. This study assessed the characteristics of 36 SCD patients undergoing renal transplantation. Immediate post-surgical complications occurred in 25% of cases. Cytomegalovirus and bacterial infections were frequently observed. Twelve patients died after a median follow-up period of17-4 months. Overall patient survival was significantly lower in SCD than in the control group without significant difference for overall death-censored graft sur-vival. Our data suggest that renal transplantation should be systematically considered in SCD patients with end-stage renal disease.
Document type :
Journal articles
Complete list of metadatas

https://www.hal.inserm.fr/inserm-02285824
Contributor : Ana Paula Dutra Azevedo <>
Submitted on : Friday, September 13, 2019 - 10:25:51 AM
Last modification on : Friday, October 4, 2019 - 1:10:54 AM

Identifiers

Citation

Christel Gérardin, Anissa Moktefi, Cécile Couchoud, Alyette Duquesne, Nacera Ouali, et al.. Survival and specific outcome of sickle cell disease patients after renal transplantation. British Journal of Haematology, Wiley, 2019, ⟨10.1111/bjh.16113⟩. ⟨inserm-02285824⟩

Share

Metrics

Record views

35