The microanatomic segregation of selection by apoptosis in the germinal center, Science, vol.358, p.28935768, 2017. ,
Germinal center founder cells display propensity for apoptosis before onset of somatic mutation, J Exp Med, vol.185, p.9053456, 1997. ,
Control systems and decision making for antibody production, Nat Immunol, vol.11, p.20644574, 2010. ,
AID-driven deletion causes immunoglobulin heavy chain locus suicide recombination in B cells, Science, vol.336, p.22539552, 2012. ,
The IgH locus 3' regulatory region: pulling the strings from behind, Adv Immunol, vol.110, pp.27-70, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00696444
A class switch control region at the 3' end of the immunoglobulin heavy chain locus, Cell, vol.77, p.8205622, 1994. ,
Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination, Immunity, vol.15, p.11520455, 2001. ,
The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells, J Exp Med, vol.210, p.23825188, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-00903790
Elucidation of IgH 3' region regulatory role during class switch recombination via germline deletion, Nat Commun, vol.6, p.25959683, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01212563
Genomic deletion of the whole IgH 3' regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes, Blood, vol.116, p.20538806, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-00514236
The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection, Oncotarget, p.28088785, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01567757
Palindromic structure of the IgH 3'locus control region, Nat Genet, vol.14, p.8782813, 1996. ,
Synergies between regulatory elements of the immunoglobulin heavy chain locus and its palindromic 3' locus control region, Eur J Immunol, vol.28, pp.3048-3056, 1998. ,
Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3' regulatory region, Nat Commun, vol.7, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01442466
Functional anatomy of the immunoglobulin heavy chain 3? super-enhancer needs not only core enhancer elements but also their unique DNA context, Nucleic Acids Res, vol.45, p.28369649, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01567750
Identification of a homolog of the C alpha 3'/hs3 enhancer and of an allelic variant of the 3'IgH/hs1,2 enhancer downstream of the human immunoglobulin alpha 1 gene, Eur J Immunol, vol.27, p.9394827, 1997. ,
Enhancer complexes located downstream of both human immunoglobulin Calpha genes, J Exp Med, vol.186, p.9294139, 1997. ,
Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA, Genes Dev, vol.18, p.15231739, 2004. ,
AID Recognizes Structured DNA for Class Switch Recombination, Mol Cell, vol.67, p.28757211, 2017. ,
Re-evaluation of G-quadruplex propensity with G4Hunter, Nucleic Acids Res, vol.44, pp.1746-1759, 2016. ,
A New Computational Tool Designed for Automatic Analysis of Class Switch Recombination Junctions Sequenced by High-Throughput Sequencing, J Immunol, vol.198, p.28416601, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01567748
CXCR4 expression functionally discriminates centroblasts versus centrocytes within human germinal center B cells, J Immunol, vol.182, p.19494283, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00869387
Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat, Blood, vol.103, p.14962903, 2004. ,
URL : https://hal.archives-ouvertes.fr/hal-00023269
Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes, Nat Immunol, vol.12, p.21113164, 2011. ,
The role of G-density in switch region repeats for immunoglobulin class switch recombination, Nucleic Acids Res, vol.42, p.25378327, 2014. ,
Activities of human exonuclease 1 that promote cleavage of transcribed immunoglobulin switch regions, Proc Natl Acad Sci USA, vol.105, p.18940926, 2008. ,
G-quadruplex DNA targeting alters class-switch recombination in B cells and attenuates allergic inflammation, J Allergy Clin Immunol, p.29935221, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02179335
RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination, Mol Cell, vol.70, p.29731414, 2018. ,
Tissue distribution and dependence of responsiveness of human antigen-specific memory B cells, J Immunol, vol.192, p.24567530, 2014. ,
Antigenic phenotype and functional characterization of human tonsil B cells, Blood, vol.71, p.2451545, 1988. ,
Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region, J Exp Med, vol.211, p.24752300, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01212566
Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes, Cell, vol.147, p.21962510, 2011. ,
Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells, Cell Reports, vol.13, p.26565917, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01219671