. Technical-expertise and . J. Dr, Smith for the His-HBO1 plasmid, Dr. K. Struhl for the HA-p53 plasmid, Dr. Trouche for the HA-Tip60 plasmid and Dr. Yang for the Flag-MOZ plasmid. GRANT SUPPORT This work was supported by the National Institutes of Health grant, Dr. J. Boyes for the Flag-p300 plasmid, Dr. J. Côté for the HA-HBO1 plasmid, Dr. M

J. P. Kruse and W. Gu, Modes of p53 regulation, Cell, vol.137, pp.609-622, 2009.

W. S. El-deiry, T. Tokino, V. E. Velculescu, D. B. Levy, R. Parsons et al., WAF1, a potential mediator of p53 tumor suppression, Cell, vol.75, pp.817-825, 1993.

J. W. Harper, G. R. Adami, N. Wei, K. Keyomarsi, and S. J. Elledge, The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases, Cell, vol.75, pp.805-816, 1993.

M. B. Kastan, Q. Zhan, W. S. El-deiry, F. Carrier, T. Jacks et al., A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia, Cell, vol.71, pp.587-597, 1992.

Y. Aylon and M. Oren, Living with p53, dying of p53, Cell, vol.130, pp.597-600, 2007.

K. H. Vousden and C. Prives, Blinded by the Light: The Growing Complexity of p53, Cell, vol.137, pp.413-431, 2009.

Y. Tang, W. Zhao, Y. Chen, Y. Zhao, and W. Gu, Acetylation is indispensable for p53 activation, Cell, vol.133, pp.612-626, 2008.

J. Luo, M. Li, Y. Tang, M. Laszkowska, R. G. Roeder et al., Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo, Proc Natl Acad Sci U S A, vol.101, pp.2259-2264, 2004.

W. Gu and R. G. Roeder, Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain, Cell, vol.90, pp.595-606, 1997.

K. Sakaguchi, J. E. Herrera, S. Saito, T. Miki, M. Bustin et al., DNA damage activates p53 through a phosphorylation-acetylation cascade, Genes Dev, vol.12, pp.2831-2841, 1998.

M. Li, J. Luo, C. L. Brooks, and W. Gu, Acetylation of p53 inhibits its ubiquitination by Mdm2, The Journal of biological chemistry, vol.277, pp.50607-50611, 2002.

A. Ito, C. H. Lai, X. Zhao, S. Saito, M. H. Hamilton et al., p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2, Embo J, vol.20, pp.1331-1340, 2001.

N. A. Barlev, L. Liu, N. H. Chehab, K. Mansfield, K. G. Harris et al., Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases, Mol Cell, vol.8, pp.1243-1254, 2001.

J. M. Espinosa and B. M. Emerson, Transcriptional Regulation by p53 through Intrinsic DNA/Chromatin Binding and SiteDirected Cofactor Recruitment, Mol Cell, vol.8, pp.57-69, 2001.

Y. H. Wang, Y. G. Tsay, B. C. Tan, W. Y. Lo, and S. C. Lee, Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305, The Journal of biological chemistry, vol.278, pp.25568-25576, 2003.

S. M. Reed and D. E. Quelle, p53 Acetylation: Regulation and Consequences, vol.7, pp.30-69, 2014.

M. Iizuka, O. F. Sarmento, T. Sekiya, H. Scrable, C. D. Allis et al., Hbo1 Links p53-dependent stress signaling to DNA replication licensing, Molecular and cellular biology, vol.28, pp.140-153, 2008.

N. Avvakumov, M. E. Lalonde, N. Saksouk, E. Paquet, K. C. Glass et al., Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferation, Molecular and cellular biology, vol.32, pp.689-703, 2012.
URL : https://hal.archives-ouvertes.fr/hal-02154207

M. Georgiakaki, N. Chabbert-buffet, B. Dasen, G. Meduri, S. Wenk et al., Ligand-controlled interaction of histone acetyltransferase binding to ORC-1 (HBO1) with the N-terminal transactivating domain of progesterone receptor induces steroid receptor coactivator 1-dependent coactivation of transcription, Mol Endocrinol, vol.20, pp.2122-2140, 2006.

B. Miotto, T. Sagnier, H. Berenger, D. Bohmann, J. Pradel et al., Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis, Genes Dev, vol.20, pp.101-112, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00088587

B. Miotto and K. Struhl, Differential gene regulation by selective association of transcriptional coactivators and bZIP DNA-binding domains, Molecular and cellular biology, vol.26, pp.5969-5982, 2006.
URL : https://hal.archives-ouvertes.fr/inserm-02132531

M. Iizuka, T. Matsui, H. Takisawa, and M. M. Smith, Regulation of replication licensing by acetyltransferase Hbo1, Molecular and cellular biology, vol.26, pp.1098-1108, 2006.

B. Miotto and K. Struhl, HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1, Genes Dev, vol.22, pp.2633-2638, 2008.
URL : https://hal.archives-ouvertes.fr/inserm-02132585

B. Vogelstein, Cancer. A deadly inheritance, Nature, vol.348, pp.681-682, 1990.

L. Pasqualucci, D. Dominguez-sola, A. Chiarenza, G. Fabbri, A. Grunn et al., Inactivating mutations of acetyltransferase genes in B-cell lymphoma, Nature, vol.471, pp.189-195, 2011.

C. G. Mullighan, J. Zhang, L. H. Kasper, S. Lerach, D. Payneturner et al., CREBBP mutations in relapsed acute lymphoblastic leukaemia, Nature, vol.471, pp.235-239, 2011.

A. Inthal, P. Zeitlhofer, M. Zeginigg, M. Morak, R. Grausenburger et al., CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia, Leukemia, vol.26, pp.1797-1803, 2012.

M. Matsuoka and K. T. Jeang, Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation, Nat Rev Cancer, vol.7, pp.270-280, 2007.

S. Sugito, K. Yamato, Y. Sameshima, J. Yokota, S. Yano et al., Adult T-cell leukemia: structures and expression of the p53 gene, Int J Cancer, vol.49, pp.880-885, 1991.

H. Nagai, T. Kinoshita, J. Imamura, Y. Murakami, K. Hayashi et al., Genetic alteration of p53 in some patients with adult T-cell leukemia, Jpn J Cancer Res, vol.82, pp.1421-1427, 1991.

A. Cereseto, F. Diella, J. C. Mulloy, A. Cara, P. Michieli et al., p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells, Blood, vol.88, pp.1551-1560, 1996.

T. Akagi, H. Ono, N. Tsuchida, and K. Shimotohno, Aberrant expression and function of p53 in T-cells immortalized by HTLV-I Tax1, FEBS Lett, vol.406, pp.263-266, 1997.

K. Van-orden, H. A. Giebler, I. Lemasson, M. Gonzales, and J. K. Nyborg, Binding of p53 to the KIX domain of CREB binding protein. A potential link to human T-cell leukemia virus, type I-associated leukemogenesis, J Biol Chem, vol.274, pp.26321-26328, 1999.

Y. Ariumi, A. Kaida, J. Y. Lin, M. Hirota, O. Masui et al., HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration, Oncogene, vol.19, pp.1491-1499, 2000.

C. A. Pise-masison, R. Mahieux, M. F. Radonovich, H. Jiang, and J. N. Brady, Human T-lymphotropic virus type-I-tax protein Utilizes distinct pathways for p53 Inhibition which are cell-type dependent, The Journal of biological chemistry, 2000.

A. Miyazato, S. Sheleg, H. Iha, Y. Li, and K. T. Jeang, Evidence for NF-kappaB-and CBP-independent repression of p53's transcriptional activity by human T-cell leukemia virus type 1 Tax in mouse embryo and primary human fibroblasts, Journal of virology, vol.79, pp.9346-9350, 2005.

S. Tamiya, M. Matsuoka, K. Etoh, T. Watanabe, S. Kamihira et al., Two types of defective human T-lymphotropic virus type I provirus in adult T-cell leukemia, Blood, vol.88, pp.3065-3073, 1996.

T. Koiwa, A. Hamano-usami, T. Ishida, A. Okayama, K. Yamaguchi et al., 5?-long terminal repeat-selective CpG methylation of latent human T-cell leukemia virus type 1 provirus in vitro and in vivo, Journal of virology, vol.76, pp.9389-9397, 2002.

S. Takeda, M. Maeda, S. Morikawa, Y. Taniguchi, J. Yasunaga et al., Genetic and epigenetic inactivation of tax gene in adult T-cell leukemia cells, Int J Cancer, vol.109, pp.559-567, 2004.

Y. Satou, J. Yasunaga, M. Yoshida, and M. Matsuoka, HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells, Proc Natl Acad Sci, vol.103, pp.720-725, 2006.

K. Murata, T. Hayashibara, K. Sugahara, A. Uemura, T. Yamaguchi et al., A novel alternative splicing isoform of human T-cell leukemia virus type 1 bZIP factor (HBZ-SI) targets distinct subnuclear localization, Journal of virology, vol.80, pp.2495-2505, 2006.

G. Gaudray, F. Gachon, J. Basbous, M. Biard-piechaczyk, C. Devaux et al., The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription, J Virol, vol.76, pp.12813-12822, 2002.
URL : https://hal.archives-ouvertes.fr/hal-00188771

I. Clerc, N. Polakowski, C. Andre-arpin, P. Cook, B. Barbeau et al., An interaction between the human T cell leukemia virus type 1 basic leucine zipper factor (HBZ) and the KIX domain of p300/CBP contributes to the down-regulation of tax-dependent viral transcription by HBZ, The Journal of biological chemistry, vol.283, pp.23903-23913, 2008.
URL : https://hal.archives-ouvertes.fr/hal-02152795

T. Wurm, D. G. Wright, N. Polakowski, J. M. Mesnard, and I. Lemasson, The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP, Nucleic acids research, vol.40, pp.5910-5925, 2012.
URL : https://hal.archives-ouvertes.fr/hal-02120125

M. Cavanagh, S. Landry, B. Audet, C. Arpin-andre, P. Hivin et al.,

J. Mesnard, HTLV-I antisense transcripts initiate in the 3?LTR and are alternatively spliced and polyadenylated, Retrovirology, vol.3, p.15, 2006.

T. Riley, E. Sontag, P. Chen, and A. Levine, Transcriptional control of human p53-regulated genes, Nat Rev Mol Cell Biol, vol.9, pp.402-412, 2008.

T. Zhao, Y. Satou, K. Sugata, P. Miyazato, P. L. Green et al., HTLV-1 bZIP factor enhances TGF-beta signaling through p300 coactivator, Blood, vol.118, pp.1865-1876, 2011.

B. Leroy, L. Girard, A. Hollestelle, J. D. Minna, A. F. Gazdar et al., Analysis of TP53 mutation status in human cancer cell lines: a reassessment, Hum Mutat, vol.35, pp.756-765, 2014.

A. Petitjean, E. Mathe, S. Kato, C. Ishioka, S. V. Tavtigian et al., Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database, Hum Mutat, vol.28, pp.622-629, 2007.

H. A. Giebler, I. Lemasson, and J. K. Nyborg, p53 recruitment of CREB binding protein mediated through phosphorylated CREB: a novel pathway of tumor suppressor regulation, Mol Cell Biol, vol.20, pp.4849-4858, 2000.

I. Lemasson and J. K. Nyborg, Human T-cell leukemia virus type I Tax repression of p73beta is mediated through competition for the C/H1 domain of CBP, J Biol Chem, vol.276, pp.15720-15727, 2001.

Y. Xiao, Y. Nagai, G. Deng, T. Ohtani, Z. Zhu et al., Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60, Cell Rep, vol.7, pp.1471-1480, 2014.

J. Cheng and M. Haas, Frequent mutations in the p53 tumor suppressor gene in human leukemia T-cell lines, Molecular and cellular biology, vol.10, pp.5502-5509, 1990.

J. Yeargin, J. Cheng, and M. Haas, Role of the p53 tumor suppressor gene in the pathogenesis and in the suppression of acute lymphoblastic T-cell leukemia, Leukemia, vol.6, pp.85-91, 1992.

M. Scheffner, B. A. Werness, J. M. Huibregtse, A. J. Levine, and P. M. Howley, The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53, Cell, vol.63, pp.1129-1136, 1990.

M. Nagashima, M. Shiseki, K. Miura, K. Hagiwara, S. P. Linke et al., DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53, Proc Natl Acad Sci U S A, vol.98, pp.9671-9676, 2001.

L. Liu, D. M. Scolnick, R. C. Trievel, H. B. Zhang, R. Marmorstein et al., p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage, Mol Cell Biol, vol.19, pp.1202-1209, 1999.

Y. Tang, J. Luo, W. Zhang, and W. Gu, Tip60-dependent acetylation of p53 modulates the decision between cellcycle arrest and apoptosis, Mol Cell, vol.24, pp.827-839, 2006.

S. M. Sykes, H. S. Mellert, M. A. Holbert, K. Li, R. Marmorstein et al., Acetylation of the p53 DNAbinding domain regulates apoptosis induction, Mol Cell, vol.24, pp.841-851, 2006.

S. Rokudai, O. Laptenko, S. M. Arnal, Y. Taya, I. Kitabayashi et al., MOZ increases p53 acetylation and premature senescence through its complex formation with PML, Proc Natl Acad Sci U S A, vol.110, pp.3895-3900, 2013.

B. Miotto and K. Struhl, HBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by Geminin, Mol Cell, vol.37, pp.57-66, 2010.
URL : https://hal.archives-ouvertes.fr/inserm-02132583

N. Simonis, J. F. Rual, I. Lemmens, M. Boxus, T. Hirozanekishikawa et al., Hostpathogen interactome mapping for HTLV-1 and -2 retroviruses, Retrovirology, vol.9, p.26, 2012.
URL : https://hal.archives-ouvertes.fr/inserm-00697435

K. Hagiya, J. Yasunaga, Y. Satou, K. Ohshima, and M. Matsuoka, ATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells, Retrovirology, vol.8, p.19, 2011.

N. Polakowski, H. Gregory, J. M. Mesnard, and I. Lemasson, Expression of a protein involved in bone resorption, Dkk1, is activated by HTLV-1 bZIP factor through its activation domain, Retrovirology, vol.7, p.61, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00509059

A. Tanaka-nakanishi, J. Yasunaga, K. Takai, and M. Matsuoka, HTLV-1 bZIP factor suppresses apoptosis by attenuating the function of FoxO3a and altering its localization, Cancer research, vol.74, pp.188-200, 2014.

Y. Mitobe, J. Yasunaga, R. Furuta, and M. Matsuoka, HTLV-1 bZIP Factor RNA and Protein Impart Distinct Functions on T-cell Proliferation and Survival, Cancer research, vol.75, pp.4143-4152, 2015.

T. Waldman, K. W. Kinzler, and B. Vogelstein, p21 is necessary for the p53-mediated G1 arrest in human cancer cells, Cancer research, vol.55, pp.5187-5190, 1995.

F. Bunz, A. Dutriaux, C. Lengauer, T. Waldman, S. Zhou et al., Requirement for p53 and p21 to sustain G2 arrest after DNA damage, Science, vol.282, pp.1497-1501, 1998.

S. Bates, K. M. Ryan, A. C. Phillips, and K. H. Vousden, Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression, Oncogene, vol.17, pp.1691-1703, 1998.

V. Dulic, G. H. Stein, D. F. Far, and S. I. Reed, Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/ M-phase transition, Molecular and cellular biology, vol.18, pp.546-557, 1998.

R. H. Medema, R. Klompmaker, V. A. Smits, and G. Rijksen, p21waf1 can block cells at two points in the cell cycle, www.impactjournals.com/oncotarget but does not interfere with processive DNA-replication or stress-activated kinases, Oncogene, vol.16, pp.431-441, 1998.

A. B. Niculescu, X. Chen, M. Smeets, L. Hengst, C. Prives et al., Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication, Molecular and cellular biology, vol.18, pp.629-643, 1998.

N. N. Kreis, F. Louwen, and J. Yuan, Less understood issues: p21(Cip1) in mitosis and its therapeutic potential, Oncogene, vol.34, pp.1758-1767, 2015.

X. W. Wang, Q. Zhan, J. D. Coursen, M. A. Khan, H. U. Kontny et al., GADD45 induction of a G2/M cell cycle checkpoint, Proc Natl Acad Sci U S A, vol.96, pp.3706-3711, 1999.

Q. Zhan, M. J. Antinore, X. W. Wang, F. Carrier, M. L. Smith et al., Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45, Oncogene, vol.18, pp.2892-2900, 1999.

S. Jin, T. Tong, W. Fan, F. Fan, M. J. Antinore et al., GADD45-induced cell cycle G2-M arrest associates with altered subcellular distribution of cyclin B1 and is independent of p38 kinase activity, Oncogene, vol.21, pp.8696-8704, 2002.

J. Arnold, B. Zimmerman, M. Li, M. D. Lairmore, and P. L. Green, Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation, Blood, vol.112, pp.3788-3797, 2008.

N. L. Lill, S. R. Grossman, D. Ginsberg, J. Decaprio, and D. M. Livingston, Binding and modulation of p53 by p300/ CBP coactivators, Nature, vol.387, pp.823-827, 1997.

W. Gu, X. L. Shi, and R. G. Roeder, Synergistic activation of transcription by CBP and p53, Nature, vol.387, pp.819-823, 1997.

M. E. Lalonde, X. Cheng, and J. Cote, Histone target selection within chromatin: an exemplary case of teamwork, Genes Dev, vol.28, pp.1029-1041, 2014.

K. H. Mcconnell, M. Dixon, and B. R. Calvi, The histone acetyltransferases CBP and Chameau integrate developmental and DNA replication programs in Drosophila ovarian follicle cells, Development, vol.139, pp.3880-3890, 2012.

M. A. Glozak and E. Seto, Acetylation/deacetylation modulates the stability of DNA replication licensing factor Cdt1, The Journal of biological chemistry, vol.284, pp.11446-11453, 2009.

C. D. Knights, J. Catania, D. Giovanni, S. Muratoglu, S. Perez et al., Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate, J Cell Biol, vol.173, pp.533-544, 2006.

S. J. Marriott and O. J. Semmes, Impact of HTLV-I Tax on cell cycle progression and the cellular DNA damage repair response, Oncogene, vol.24, pp.5986-5995, 2005.

M. Watanabe, S. Nakahata, M. Hamasaki, Y. Saito, Y. Kawano et al., Downregulation of CDKN1A in adult T-cell leukemia/lymphoma despite overexpression of CDKN1A in human T-lymphotropic virus 1-infected cell lines, Journal of virology, vol.84, pp.6966-6977, 2010.

J. G. Jackson and O. M. Pereira-smith, p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts, Cancer research, vol.66, pp.8356-8360, 2006.

Y. L. Kuo and C. Z. Giam, Activation of the anaphase promoting complex by HTLV-1 tax leads to senescence, Embo J, vol.25, pp.1741-1752, 2006.

H. Zhi, L. Yang, Y. L. Kuo, Y. K. Ho, H. M. Shih et al., NFkappaB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ, PLoS Pathog, vol.7, p.1002025, 2011.

T. Zhao, J. Yasunaga, Y. Satou, M. Nakao, M. Takahashi et al., Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NFkappaB, Blood, vol.113, pp.2755-2764, 2009.

A. S. Kuhlmann, J. Villaudy, L. Gazzolo, M. Castellazzi, J. M. Mesnard et al., HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT), Retrovirology, vol.4, p.92, 2007.
URL : https://hal.archives-ouvertes.fr/hal-02152798

A. G. Bodnar, M. Ouellette, M. Frolkis, S. E. Holt, C. P. Chiu et al., Extension of life-span by introduction of telomerase into normal human cells, Science, vol.279, pp.349-352, 1998.

H. Vaziri and S. Benchimol, Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span, Curr Biol, vol.8, pp.279-282, 1998.

I. Lemasson, M. R. Lewis, N. Polakowski, P. Hivin, M. H. Cavanagh et al., Human T-cell leukemia virus type 1 (HTLV-1) bZIP protein interacts with the cellular transcription factor CREB to inhibit HTLV-1 transcription, Journal of virology, vol.81, pp.1543-1553, 2007.
URL : https://hal.archives-ouvertes.fr/hal-00188402

R. K. Naviaux, E. Costanzi, M. Haas, and I. M. Verma, The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses, Journal of virology, vol.70, pp.5701-5705, 1996.

J. K. Yee, T. Friedmann, and J. C. Burns, Generation of high-titer pseudotyped retroviral vectors with very broad host range, Methods Cell Biol, vol.43, pp.99-112, 1994.

Y. Doyon, C. Cayrou, M. Ullah, A. J. Landry, V. Cote et al., ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation, Mol Cell, vol.21, pp.51-64, 2006.
URL : https://hal.archives-ouvertes.fr/hal-02154286

X. J. Yang, V. V. Ogryzko, J. Nishikawa, B. H. Howard, and Y. Nakatani, A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A, Nature, vol.382, pp.319-324, 1996.

S. J. Baker, S. Markowitz, E. R. Fearon, J. K. Willson, and B. Vogelstein, Suppression of human colorectal carcinoma cell growth by wild-type p53, Science, vol.249, pp.912-915, 1990.

R. Rousset, C. Desbois, F. Bantignies, and P. Jalinot, Effects on NF-kappa B1/p105 processing of the interaction between the HTLV-1 transactivator Tax and the proteasome, Nature, vol.381, pp.328-331, 1996.

J. Boyes, P. Byfield, Y. Nakatani, and V. Ogryzko, Regulation of activity of the transcription factor GATA-1 by acetylation, Nature, vol.396, pp.594-598, 1998.

N. Champagne, N. R. Bertos, N. Pelletier, A. H. Wang, M. Vezmar et al., Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein, J Biol Chem, vol.274, pp.28528-28536, 1999.

G. Legube, L. K. Linares, C. Lemercier, M. Scheffner, S. Khochbin et al., Tip60 is targeted to proteasomemediated degradation by Mdm2 and accumulates after UV irradiation, EMBO J, vol.21, pp.1704-1712, 2002.
URL : https://hal.archives-ouvertes.fr/hal-00379764

P. R. Cook, N. Polakowski, and I. Lemasson, HTLV-1 HBZ protein deregulates interactions between cellular factors and the KIX domain of p300/CBP, J Mol Biol, vol.409, pp.384-398, 2011.

S. Cawley, S. Bekiranov, H. H. Ng, P. Kapranov, E. A. Sekinger et al., Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs, Cell, vol.116, pp.499-509, 2004.