The asthma epidemic, N Engl J Med, vol.355, issue.21, p.17124020, 2006. ,
Risk factors for asthma: is prevention possible?, Lancet, vol.386, issue.9998, p.26382999, 2015. ,
Impact of gender on asthma in childhood and adolescence: a GA2LEN review, Allergy, vol.63, issue.1, p.17822448, 2008. ,
Gender differences in asthma development and remission during transition through puberty: the TRacking Adolescents' Individual Lives Survey (TRAILS) study, J Allergy Clin Immunol, vol.126, issue.3, p.20816186, 2010. ,
Asthma is different in women, Curr Allergy Asthma Rep, vol.15, issue.6, p.28, 2015. ,
Endogenous and exogenous sex steroid hormones in asthma and allergy in females: a systematic review and meta-analysis, J Allergy Clin Immunol, vol.141, issue.4, p.29305316, 2018. ,
Gomez Real F. Respiratory health in women: from menarche to menopause, Exp Rev Resp Med, vol.6, issue.2, p.22455491, 2012. ,
Mendelian randomisation study of childhood BMI and early menarche, J Obes, p.21773002, 2011. ,
Age at menarche and risk of asthma: systematic review and meta-analysis, J Asthma, vol.51, issue.6, p.24628525, 2014. ,
Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: the UK Biobank study, Sci Rep, vol.5, p.11208, 2015. ,
Early menarche and new onset of asthma: results from the SAPALDIA cohort study, Maturitas, vol.101, p.28539170, 2017. ,
The influence of bronchial asthma on sexual maturation of girls, J Physiol Pharmacol, vol.58, issue.5, p.18204126, 2007. ,
Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?, Int J Epidemiol, vol.32, issue.1, p.12689998, 2003. ,
Mendelian randomisation and causal inference in observational epidemiology, PLoS Med, vol.5, issue.8, p.18752343, 2008. ,
UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age, PLoS Med, vol.12, issue.3, p.25826379, 2015. ,
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk, Nat Genet, vol.49, issue.6, p.28436984, 2017. ,
Using multiple genetic variants as instrumental variables for modifiable risk factors, Stat Methods Med Res, vol.21, issue.3, p.21216802, 2012. ,
Mendelian randomization: using genes as instruments for making causal inferences in epidemiology, Stat Med, vol.27, issue.8, p.17886233, 2008. ,
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations, Nucleic Acids Res, vol.42, p.24316577, 2014. ,
A navigator for human genome epidemiology, Nat Genet, vol.40, issue.2, p.18227866, 2008. ,
Genetic variation in LIN28B is associated with the timing of puberty, Nat Genet, vol.41, issue.6, p.19448623, 2009. ,
Shared genetic aetiology of puberty timing between sexes and with health-related outcomes, Nat Commun, vol.6, p.8842, 2015. ,
Detection and interpretation of shared genetic influences on 42 human traits, Nat Genet, vol.48, issue.7, p.27182965, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-02122294
Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods, Stat Med, vol.35, issue.11, p.26661904, 2016. ,
Genome-wide genetic data oñ 500,000 UK Biobank participants, 2017. ,
Instrumental variable estimation of causal risk ratios and causal odds ratios in Mendelian randomization analyses, Am J Epidemiol, vol.173, issue.12, p.21555716, 2011. ,
Assumptions of IV methods for observational epidemiology, Stat Sci, vol.25, issue.1, pp.22-40, 2010. ,
Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome, Stat Med, vol.34, issue.21, p.25950993, 2015. ,
On instrumental variables estimation of causal odds ratios, Stat Sci, vol.26, pp.403-425, 2011. ,
Statistical inference in two-sample summary data Mendelian randomization using a robust adjusted profile score. arXiv, 2018. ,
Mendelian randomization using public data from genetic consortia, Int J Biostat, vol.12, issue.2, p.27092657, 2016. ,
Mendelian randomization analysis with multiple genetic variants using summarized data, Genet Epidemiol, vol.37, issue.7, p.24114802, 2013. ,
A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization, Stat Med, vol.36, issue.11, p.28114746, 2017. ,
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression, Int J Epidemiol, vol.44, issue.2, pp.512-537, 2015. ,
Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator, Genet Epidemiol, vol.40, issue.4, p.27061298, 2016. ,
PhenoScanner: a database of human genotype-phenotype associations, Bioinformatics, vol.32, issue.20, p.27318201, 2016. ,
Assessing causality in associations between cannabis use and schizophrenia risk: a two-sample Mendelian randomization study, Psychol Med, vol.47, issue.5, p.27928975, 2017. ,
Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic, Int J Epidemiol, vol.45, issue.6, p.27616674, 2016. ,
Illustrating bias due to conditioning on a collider, Int J Epidemiol, vol.39, issue.2, pp.417-437, 2010. ,
Sexual maturation protects against development of lung inflammation through estrogen, Am J Physiol Lung Cell Mol Physiol, vol.310, issue.2, p.26608529, 2016. ,
Parity and decreased use of oral contraceptives as predictors of asthma in young women, Clin Exp Allergy, vol.36, issue.5, p.16650045, 2006. ,
Perimenstrual asthma: a syndrome without known cause or cure, J Allergy Clin Immunol, vol.112, issue.2, p.12897732, 2003. ,
Menopause, postmenopausal estrogen preparations, and the risk of adult-onset asthma. A prospective cohort study, Am J Respir Crit Care Med, vol.152, issue.4, p.7551368, 1995. ,
Detrimental psychological outcomes associated with early pubertal timing in adolescent girls, Dev Rev, vol.27, issue.2, p.20740062, 2007. ,
Evidence for a secular trend in age of menarche, N Engl J Med, vol.306, issue.17, p.7062994, 1982. ,
Menstruation in adolescents: what's normal, what's not, Ann N Y Acad Sci, vol.1135, p.18574205, 2008. ,
What is in our environment that effects puberty?, Reprod Toxicol, vol.44, p.23602892, 2014. ,
Global burden of obesity in 2005 and projections to 2030, Int J Obes (Lond), vol.32, issue.9, p.18607383, 2008. ,
Epigenetic effects of endocrine-disrupting chemicals on female reproduction: an ovarian perspective, Front Neuroendocrinol, vol.31, issue.4, p.20609371, 2010. ,
Age at menarche and adult BMI in the Aberdeen children of the 1950s cohort study, Am J Clin Nutr, vol.82, issue.4, p.16210700, 2005. ,
Age at menarche and risk of ovarian cancer: a metaanalysis of epidemiological studies, Int J Cancer, vol.132, issue.12, p.23175139, 2013. ,
Age at menarche and risk of type 2 diabetes: results from 2 large prospective cohort studies, Am J Epidemiol, vol.171, issue.3, pp.334-378, 2010. ,
Age at menarche, age at menopause, height and obesity as risk factors for breast cancer: associations and interactions in an international case-control study, Int J Cancer, vol.46, issue.5, p.2228308, 1990. ,
Early age at menarche associated with cardiovascular disease and mortality, J Clin Endocrinol Metab, vol.94, issue.12, pp.4953-60, 2009. ,
Early age at menarche, lung function, and adult asthma, Am J Respir Crit Care Med, vol.183, issue.1, p.20732985, 2011. ,
Age at menarche and lung function: a Mendelian randomization study, Eur J Epidemiol, vol.32, issue.8, p.28624884, 2017. ,
Age at menarche and adult body mass index: a Mendelian randomization study, Int J Obes, 2018. ,
Mendelian randomization: genetic anchors for causal inference in epidemiological studies, Hum Mol Genet, vol.23, issue.R1, p.25064373, 2014. ,
Changes in the male voice at puberty, Arch Dis Child, vol.77, issue.5, p.9487971, 1997. ,
Timing of voice breaking in males associated with growth and weight gain across the life course, J Clin Endocrinol Metab, vol.97, issue.8, p.22654120, 2012. ,