S. W. Ryter, J. Alam, and A. M. Choi, Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications, Physiol. Rev, vol.86, pp.583-650, 2006.

S. Tsuchihashi, C. Fondevila, and J. W. Kupiec-weglinski, Heme oxygenase system in ischemia and reperfusion injury, Ann. Transplant, vol.9, pp.84-87, 2004.

P. Blancou, V. Tardif, T. Simon, S. Rémy, L. J. Carreno et al.,

, Methods Mol. Biol, vol.677, pp.247-68, 2011.

L. E. Otterbein, S. L. Otterbein, E. Ifedigbo, F. Liu, D. E. Morse et al., MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury, Am. J. Pathol, vol.163, pp.2555-2563, 2003.

D. Bouche, C. Chauveau, J. C. Roussel, P. Mathieu, C. Braudeau et al., Inhibition of graft arteriosclerosis development in rat aortas following heme oxygenase-1 gene transfer, Transpl. Immunol, vol.9, pp.235-238, 2002.

C. Chauveau, S. Remy, P. J. Royer, M. Hill, S. Tanguy-royer et al., Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression, Blood, vol.106, pp.1694-1702, 2005.

A. A. Chora, P. Fontoura, A. Cunha, T. F. Pais, S. Cardoso et al., Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation, J. Clin. Invest, vol.117, pp.438-447, 2007.

Z. W. Xia, W. W. Zhong, L. Q. Xu, J. L. Sun, Q. X. Shen et al.,

, + CD25 high regulatory T cells suppress allergic airway inflammation, J. Immunol, vol.177, pp.5936-5945, 2006.

C. Braudeau, D. Bouchet, L. Tesson, S. Iyer, S. Remy et al., Induction of long-term cardiac allograft survival by heme oxygenase-1 gene transfer, Gene Ther, vol.11, pp.701-710, 2004.

, carbon monoxide delivery inhibit chronic rejection, Am. J. Transplant, vol.2, pp.581-592, 2002.

H. M. Clarke, S. Shrivastava, R. Motterlini, P. Sawle, D. Chen et al., Donor HO-1 expression inhibits intimal hyperplasia in unmanipulated graft recipients: a potential role for CD8+ T-cell modulation by carbon monoxide, Transplantation, vol.88, pp.653-661, 2009.

M. Li, S. Peterson, D. Husney, M. Inaba, K. Guo et al., Long-lasting expression of HO-1 delays progression of type I diabetes in NOD mice, Cell Cycle, vol.6, pp.567-571, 2007.

M. P. Soares, Y. Lin, J. Anrather, E. Csizmadia, K. Takigami et al., Expression of heme oxygenase-1 can determine cardiac xenograft survival, Nat. Med, vol.4, pp.1073-1077, 1998.

A. A. Herrada, C. Llanos, J. P. Mackern-oberti, L. J. Carreno, C. Henriquez et al., Heme oxygenase 1 expression is altered in monocytes from patients with systemic lupus erythematosus, Immunology, vol.136, pp.414-424, 2012.

S. Remy, P. Blancou, L. Tesson, V. Tardif, R. Brion et al., Carbon monoxide inhibits TLR-induced dendritic cell immunogenicity, J. Immunol, vol.182, pp.1877-1884, 2009.

K. Kotsch, P. N. Martins, R. Klemz, U. Janssen, B. Gerstmayer et al., Heme oxygenase-1 ameliorates ischemia/reperfusion injury by targeting dendritic cell maturation and migration, Antioxid. Redox Signal, vol.9, pp.2049-2063, 2007.

J. Listopad, K. Asadullah, C. Sievers, T. Ritter, C. Meisel et al., Heme oxygenase-1 inhibits T cell-dependent skin inflammation and differentiation and function of antigen-presenting cells, Exp. Dermatol, vol.16, pp.661-670, 2007.

T. Simon, S. Pogu, V. Tardif, K. Rigaud, S. Remy et al., Carbon monoxide-treated dendritic cells decrease beta1-integrin induction on CD8(+) T cells and protect from type 1 diabetes, Eur. J. Immunol, vol.43, pp.209-218, 2013.

G. Basha, K. Omilusik, A. Chavez-steenbock, A. T. Reinicke, N. Lack et al., A CD74-dependent MHC class I endolysosomal cross-presentation pathway, Nat. Immunol, vol.13, pp.237-245, 2012.

S. Burgdorf, A. Kautz, V. Bohnert, P. A. Knolle, and C. Kurts, Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation, Science, vol.316, pp.612-616, 2007.

C. V. Harding and H. J. Geuze, Immunogenic peptides bind to class II MHC molecules in an early lysosomal compartment, J. Immunol, vol.151, pp.3988-3998, 1993.

G. Basha, G. Lizee, A. T. Reinicke, R. P. Seipp, K. D. Omilusik et al., MHC class I endosomal and lysosomal trafficking coincides with exogenous antigen loading in dendritic cells, PLoS One, vol.3, p.3247, 2008.

S. Burgdorf, C. Scholz, A. Kautz, R. Tampe, and C. Kurts, Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation, Nat. Immunol, vol.9, pp.558-566, 2008.

J. Neefjes and C. Sadaka, Into the intracellular logistics of crosspresentation, Front. Immunol. 2012, vol.3, pp.1-6

A. Chow, D. Toomre, W. Garrett, and I. Mellman, Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane, Nature, vol.418, pp.988-994, 2002.

K. Inaba, S. Turley, T. Iyoda, F. Yamaide, S. Shimoyama et al., The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli, J. Exp. Med, vol.191, pp.927-936, 2000.

O. V. Vieira, C. Bucci, R. E. Harrison, W. S. Trimble, L. Lanzetti et al., Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase, Mol. Cell. Biol, vol.23, pp.2501-2514, 2003.

T. Wang, Z. Ming, W. Xiaochun, and W. Hong, Rab7: role of its protein interaction cascades in endo-lysosomal traffic, Cell Signal, vol.23, pp.516-521, 2011.

T. E. Tjelle, A. Brech, L. K. Juvet, G. Griffiths, and T. Berg, Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation, J. Cell Sci, vol.109, pp.2905-2914, 1996.

E. B. Compeer, T. W. Flinsenberg, S. G. Van-der-grein, and M. Boes, Antigen processing and remodeling of the endosomal pathway: requirements for antigen cross-presentation, Front. Immunol. 2012, vol.3, pp.1-111

M. Kovacsovics-bankowski and K. L. Rock, A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules, Science, vol.267, pp.243-246, 1995.

M. Gromme, F. G. Uytdehaag, H. Janssen, J. Calafat, R. S. Van-binnendijk et al., Recycling MHC class I molecules and endosomal peptide loading, Proc. Natl. Acad. Sci, vol.96, pp.10326-10331, 1999.

G. Lizee, G. Basha, J. Tiong, J. P. Julien, M. Tian et al., Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain, Nat. Immunol, vol.4, pp.1065-1073, 2003.

M. Sugita and M. B. Brenner, Association of the invariant chain with major histocompatibility complex class I molecules directs trafficking to endocytic compartments, J. Biol. Chem, vol.270, pp.1443-1448, 1995.

C. V. Harding and H. J. Geuze, Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells, J. Cell. Biol, vol.119, pp.531-542, 1992.

A. Dani, A. Chaudhry, P. Mukherjee, D. Rajagopal, S. Bhatia et al., The pathway for MHC II-mediated presentation of endogenous proteins involves peptide transport to the endo-lysosomal compartment, J. Cell Sci, vol.117, pp.4219-4230, 2004.

S. J. Turley, K. Inaba, W. S. Garrett, M. Ebersold, J. Unternaehrer et al., Transport of peptide-MHC class II complexes in developing dendritic cells, Science, vol.288, pp.522-527, 2000.

E. S. Trombetta, M. Ebersold, W. Garrett, M. Pypaert, and I. Mellman, Activation of lysosomal function during dendritic cell maturation, Science, vol.299, pp.1400-1403, 2003.

A. A. Herrada, F. J. Contreras, J. A. Tobar, R. Pacheco, and A. M. Kalergis, Immune complex-induced enhancement of bacterial antigen presentation requires Fcgamma receptor III expression on dendritic cells, Proc. Natl. Acad. Sci, vol.104, pp.13402-13407, 2007.

S. A. Riquelme, S. M. Bueno, and A. M. Kalergis, IgG keeps virulent Salmonella from evading dendritic cell uptake, Immunology, vol.136, pp.291-305, 2012.

M. P. Stein, J. Dong, and A. Wandinger-ness, Rab proteins and endocytic trafficking: potential targets for therapeutic intervention, Adv. Drug Delivery Rev, vol.55, pp.1421-1437, 2003.

D. L. Clemens, B. Y. Lee, and M. A. Horwitz, Mycobacterium tuberculosis and Legionella pneumophila phagosomes exhibit arrested maturation despite acquisition of Rab7, Infect. Immun, vol.68, pp.5154-5166, 2000.

S. M. Bueno, S. Riquelme, C. A. Riedel, and A. M. Kalergis, Mechanisms used by virulent Salmonella to impair dendritic cell function and evade adaptive immunity, Immunology, vol.137, pp.28-36, 2012.

C. , W. Gmbh, &. Co, and . Kgaa,

, Eur. J. Immunol, vol.43, pp.2832-2844, 2013.

S. A. Riquelme, A. Wozniak, A. M. Kalergis, and S. M. Bueno, Evasion of host immunity by virulent Salmonella: implications for vaccine design

, Curr. Med. Chem, vol.18, pp.5666-5675, 2011.

Y. Wang, T. Chen, C. Han, D. He, H. Liu et al., Lysosomeassociated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4, Blood, vol.110, pp.962-971, 2007.

C. Progida, L. Cogli, F. Piro, A. De-luca, O. Bakke et al., Rab7b controls trafficking from endosomes to the TGN, J. Cell Sci, vol.123, pp.1480-1491, 2010.

M. Yang, T. Chen, C. Han, N. Li, T. Wan et al., Rab7b, a novel lysosome-associated small GTPase, is involved in monocytic differentiation of human acute promyelocytic leukemia cells, Biochem. Biophys. Res. Commun, vol.318, pp.792-799, 2004.

P. Guermonprez, L. Saveanu, M. Kleijmeer, J. Davoust, P. Van-endert et al., ER-phagosome fusion defines an MHC class I crosspresentation compartment in dendritic cells, Nature, vol.425, pp.397-402, 2003.

M. Houde, S. Bertholet, E. Gagnon, S. Brunet, G. Goyette et al., Phagosomes are competent organelles for antigen cross-presentation, Nature, vol.425, pp.402-406, 2003.

A. L. Ackerman, C. Kyritsis, R. Tampe, and P. Cresswell, Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens, Proc. Natl. Acad. Sci, vol.100, pp.12889-12894, 2003.

A. L. Ackerman, C. Kyritsis, R. Tampe, and P. Cresswell, Access of soluble antigens to the endoplasmic reticulum can explain crosspresentation by dendritic cells, Nat. Immunol, vol.6, pp.107-113, 2005.

M. Desjardins, ER-mediated phagocytosis: a new membrane for new functions, Nat. Rev. Immunol, vol.3, pp.280-291, 2003.

Y. Wan, Y. Wu, J. Zhou, L. Zou, Y. Liang et al., Crosspresentation of phage particle antigen in MHC class II and endoplasmic reticulum marker-positive compartments, Eur. J. Immunol, vol.35, pp.2041-2050, 2005.

R. M. Yates and D. G. Russell, Phagosome maturation proceeds independently of stimulation of toll-like receptors 2 and 4, Immunity, vol.23, pp.409-417, 2005.

A. Shiratsuchi, I. Watanabe, O. Takeuchi, S. Akira, and Y. Nakanishi, Inhibitory effect of toll-like receptor 4 on fusion between phagosomes and endosomes/lysosomes in macrophages, J. Immunol, vol.172, pp.2039-2047, 2004.

P. Guermonprez and S. Amigorena, Pathways for antigen cross presentation, Springer Semin. Immunopathol, vol.26, pp.257-271, 2005.

T. Tamura, H. Ariga, T. Kinashi, S. Uehara, T. Kikuchi et al., The role of antigenic peptide in CD4+ T helper phenotype development in a T cell receptor transgenic model, Int. Immunol, vol.16, pp.1691-1699, 2004.

M. M. Venkataswamy, A. Baena, M. F. Goldberg, G. Bricard, J. S. Im et al., Incorporation of NKT cellactivating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis bacillus Calmette-Guerin, J. Immunol, vol.183, pp.1644-1656, 2009.

A. Lu, F. Tebar, B. Alvarez-moya, C. Lopez-alcala, M. Calvo et al., A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes, J. Cell Biol, vol.184, pp.863-879, 2009.

Q. Li, A. Lau, T. J. Morris, L. Guo, C. B. Fordyce et al., A syntaxin 1, Galpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization