G. Einecke, B. Sis, J. Reeve, M. Mengel, and P. M. Campbell, Antibodymediated microcirculation injury is the major cause of late kidney transplant failure, Am J Transplant, vol.9, pp.2520-2531, 2009.

C. Lefaucheur, A. Loupy, G. S. Hill, J. Andrade, and D. Nochy, Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation, J Am Soc Nephrol, vol.21, pp.1398-1406, 2010.

Q. Mao, P. I. Terasaki, J. Cai, K. Briley, and P. Catrou, Extremely high association between appearance of HLA antibodies and failure of kidney grafts in a five-year longitudinal study, Am J Transplant, vol.7, pp.864-871, 2007.

B. Sis, M. Mengel, M. Haas, R. B. Colvin, and P. F. Halloran, Banff '09 meeting report: antibody mediated graft deterioration and implementation of Banff working groups, Am J Transplant, vol.10, pp.464-471, 2010.

A. Loupy, G. S. Hill, C. Suberbielle, D. Charron, and D. Anglicheau, Significance of C4d Banff Scores in Early Protocol Biopsies of Kidney Transplant Recipients with Preformed Donor-Specific Antibodies (DSA), 2011.

, Am J Transplant, vol.11, pp.56-65

D. Baek, J. Villén, C. Shin, F. D. Camargo, and S. P. Gygi, The impact of microRNAs on protein output, Nature, vol.455, pp.64-71, 2008.

D. Anglicheau, V. K. Sharma, R. Ding, A. Hummel, and C. Snopkowski, MicroRNA expression profiles predictive of human renal allograft status, Proc Natl Acad Sci, vol.106, pp.5330-5335, 2009.

J. M. Lorenzen, I. Volkmann, J. Fiedler, M. Schmidt, and I. Scheffner, Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients, Am J Transplant, vol.11, pp.2221-2227, 2011.

W. Sui, Y. Dai, Y. Huang, H. Lan, and Q. Yan, Microarray analysis of MicroRNA expression in acute rejection after renal transplantation, Transpl Immunol, vol.19, pp.81-85, 2008.

M. J. Scian, D. G. Maluf, K. G. David, K. J. Archer, and J. L. Suh, MicroRNA profiles in allograft tissues and paired urines associate with chronic allograft dysfunction with IF/TA, Am J Transplant, vol.11, pp.2110-2122, 2011.
DOI : 10.1111/j.1600-6143.2011.03666.x

URL : http://europepmc.org/articles/pmc3184368?pdf=render

I. Z. Ben-dov, T. Muthukumar, P. Morozov, F. B. Mueller, and T. Tuschl, MicroRNA sequence profiles of human kidney allografts with or without tubulointerstitial fibrosis, Transplantation, vol.94, pp.1086-1094, 2012.

R. Danger, A. Pallier, M. Giral, M. Martinez-llordella, and J. J. Lozano, Upregulation of miR-142-3p in peripheral blood mononuclear cells of operationally tolerant patients with a renal transplant, J Am Soc Nephrol, vol.23, pp.597-606, 2012.

P. S. Mitchell, R. K. Parkin, E. M. Kroh, B. R. Fritz, and S. K. Wyman, Circulating microRNAs as stable blood-based markers for cancer detection, Proc Natl Acad Sci, vol.105, pp.10513-10518, 2008.

C. Ballet, K. Renaudin, N. Degauque, H. L. Mai, and F. Boeffard, Indirect CD4+ TH1 response, antidonor antibodies and diffuse C4d graft deposits in long-term recipients conditioned by donor antigens priming, Am J Transplant, vol.9, pp.697-708, 2009.
DOI : 10.1111/j.1600-6143.2009.02556.x

J. Ashton-chess, M. Giral, M. Mengel, K. Renaudin, and Y. Foucher, Tribbles-1 as a Novel Biomarker of Chronic Antibody-Mediated Rejection, J Am Soc Nephrol, vol.19, pp.1116-1127, 2008.

P. Mestdagh, P. Van-vlierberghe, D. Weer, A. Muth, D. Westermann et al., A novel and universal method for microRNA RT-qPCR data normalization, Genome Biol, vol.10, p.64, 2009.

J. J. Lozano, A. Pallier, M. Martinez-llordella, R. Danger, and M. Lopez, Comparison of transcriptional and blood cell-phenotypic markers between operationally tolerant liver and kidney recipients, Am J Transplant, vol.11, pp.1916-1926, 2011.

X. Wang, miRDB: a microRNA target prediction and functional annotation database with a wiki interface, RNA, vol.14, pp.1012-1017, 2008.

C. Z. Chen, L. Li, H. F. Lodish, and D. P. Bartel, MicroRNAs modulate hematopoietic lineage differentiation, Science, vol.303, pp.83-86, 2004.
DOI : 10.1126/science.1091903

P. Landgraf, M. Rusu, R. Sheridan, A. Sewer, and N. Iovino, A mammalian microRNA expression atlas based on small RNA library sequencing, Cell, vol.129, pp.1401-1414, 2007.
DOI : 10.1016/j.cell.2007.04.040

URL : https://hal.archives-ouvertes.fr/hal-00159802

M. L. Friedrich, M. Cui, J. B. Hernandez, B. M. Weist, and H. M. Andersen, Modulation of DRAK2 autophosphorylation by antigen receptor signaling in primary lymphocytes, J Biol Chem, vol.282, pp.4573-4584, 2007.

S. Malin, S. Mcmanus, and M. Busslinger, STAT5 in B cell development and leukemia, Curr Opin Immunol, vol.22, pp.168-176, 2010.
DOI : 10.1016/j.coi.2010.02.004

D. Olive and C. Cerdan, CD28 co-stimulation results in down-regulation of lymphotactin expression in human CD4(+) but not CD8(+) T cells via an IL-2-dependent mechanism, Eur J Immunol, vol.29, pp.2443-2453, 1999.

I. Vikstrom, S. Carotta, K. Luthje, V. Peperzak, and P. J. Jost, Mcl-1 is essential for germinal center formation and B cell memory, Science, vol.330, pp.1095-1099, 2010.

R. C. Friedman, K. K. Farh, C. B. Burge, and D. P. Bartel, Most mammalian mRNAs are conserved targets of microRNAs, Genome Res, vol.19, pp.92-105, 2009.

M. A. Lindsay, ) microRNAs and the immune response, Trends in immunology, vol.29, pp.343-351, 2008.

K. Basso, P. Sumazin, P. Morozov, C. Schneider, and R. L. Maute, Identification of the human mature B cell miRNome, Immunity, vol.30, pp.744-752, 2009.

S. Kuchen, W. Resch, A. Yamane, N. Kuo, and Z. Li, Regulation of microRNA expression and abundance during lymphopoiesis, Immunity, vol.32, pp.828-839, 2010.

X. Zhang, Z. Yan, J. Zhang, L. Gong, and W. Li, Combination of hsa-miR-375 and hsa-miR-142-5p as a predictor for recurrence risk in gastric cancer patients following surgical resection, Ann Oncol, vol.22, pp.2257-2266, 2011.

J. M. Winkler, A. D. Chaudhuri, and H. S. Fox, Translating the Brain Transcriptome in NeuroAIDS: From Non-human Primates to Humans, J Neuroimmune Pharmacol, vol.7, pp.372-379, 2012.

J. S. Schaefer, D. Montufar-solis, N. Vigneswaran, and J. R. Klein, Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-102/2 mice precedes expression in the colon, J Immunol, vol.187, pp.5834-5841, 2011.

A. Zarjou, S. Yang, A. E. Agarwal, A. Liu, and G. , Identification of a microRNA signature in renal fibrosis: Role of miR-21, Am J Physiol Renal Physiol, vol.301, pp.793-801, 2011.

K. Hamano, M. A. Rawsthorne, A. R. Bushell, P. J. Morris, and K. J. Wood, Evidence that the continued presence of the organ graft and not peripheral donor microchimerism is essential for maintenance of tolerance to alloantigen in vivo in anti-CD4 treated recipients, Transplantation, vol.62, pp.856-860, 1996.

X. Liu, L. F. Sempere, F. Galimberti, S. J. Freemantle, and C. Black, Uncovering growth-suppressive MicroRNAs in lung cancer, Clin Cancer Res, vol.15, pp.1177-1183, 2009.

S. Ding, Y. Liang, M. Zhao, G. Liang, and H. Long, Decreased miR-142-3p/5p expression causes CD4(+) T cell activation and B cell hyperstimulation in systemic lupus erythematosus, 2012.

R. L. Rossi, G. Rossetti, L. Wenandy, S. Curti, and A. Ripamonti, Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4+ T cells by the microRNA miR-125b, Nat Immunol, vol.12, pp.796-803, 2011.

J. Ashton-chess, H. L. Mai, V. Jovanovic, K. Renaudin, and Y. Foucher, Immunoproteasome beta subunit 10 is increased in chronic antibody-mediated rejection, Kidney Int, vol.77, pp.880-890, 2010.

C. Braudeau, J. Ashton-chess, M. Giral, E. Dugast, and S. Louis, Contrasted blood and intragraft toll-like receptor 4 mRNA profiles in operational tolerance versus chronic rejection in kidney transplant recipients, Transplantation, vol.86, pp.130-136, 2008.

J. G. Godwin, X. Ge, K. Stephan, A. Jurisch, and S. G. Tullius, Identification of a microRNA signature of renal ischemia reperfusion injury, Proc Natl Acad Sci, vol.107, pp.14339-14344, 2010.