J. Lerut and A. Sanchez-fueyo, An appraisal of tolerance in liver transplantation, Am J Transplant, vol.6, 2006.

G. Orlando, P. Hematti, R. J. Stratta, G. W. Burke, D. Iii et al., Clinical operational tolerance after renal transplantation: current status and future challenges, Ann Surg, vol.252, pp.915-943, 2010.

S. Brouard, A. Pallier, K. Renaudin, Y. Foucher, R. Danger et al., The natural history of clinical operational tolerance after kidney transplantation through twenty-seven cases, Am J Transplant, vol.104, pp.15448-53, 2012.

K. A. Newell, A. Asare, A. D. Kirk, T. D. Gisler, K. Bourcier et al., Identification of a B cell signature associated with renal transplant tolerance in humans, J Clin Invest, vol.120, pp.1836-1883, 2010.

P. Sagoo, E. Perucha, B. Sawitzki, S. Tomiuk, D. A. Stephens et al., Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans, J Clin Invest, vol.120, pp.1848-61, 2010.

G. Roussey-kesler, M. Giral, A. Moreau, J. Subra, C. Legendre et al., Clinical operational tolerance after kidney transplantation, Am J Transplant, vol.6, pp.736-782, 2006.

S. P. Cobbold, E. Adams, L. Graca, S. Daley, S. Yates et al., Immune privilege induced by regulatory T cells in transplantation tolerance, Immunol Rev, vol.213, pp.239-55, 2006.

M. R. Clatworthy, Targeting B cells and antibody in transplantation, Am J Transplant, vol.11, pp.1359-67, 2011.

M. D. Stegall, S. Raghavaiah, and J. M. Gloor, The (re)emergence of B cells in organ transplantation, Curr Opin Organ Transplant, vol.15, pp.451-456, 2010.

D. P. Harris, L. Haynes, P. C. Sayles, D. K. Duso, S. M. Eaton et al., Reciprocal regulation of polarized cytokine production by effector B and T cells, Nat Immunol, vol.1, pp.475-82, 2000.

M. J. Shlomchik, J. E. Craft, and M. J. Mamula, From T to B and back again: positive feedback in systemic autoimmune disease, Nat Rev Immunol, vol.1, pp.147-53, 2001.

S. I. Katz, D. Parker, and J. L. Turk, B-cell suppression of delayed hypersensitivity reactions, Nature, vol.251, pp.550-551, 1974.

R. Neta and S. B. Salvin, Specific suppression of delayed hypersensitivity: the possible presence of a suppressor B cell in the regulation of delayed hypersensitivity, J Immunol, vol.113, pp.1716-1741, 1974.

S. D. Wolf, B. N. Dittel, F. Hardardottir, and C. A. Janeway, Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice, J Exp Med, vol.184, pp.2271-78, 1996.

J. G. Evans, K. A. Chavez-rueda, A. Eddaoudi, A. Meyer-bahlburg, D. J. Rawlings et al., Novel suppressive function of transitional 2 B cells in experimental arthritis, J Immunol, vol.178, pp.7868-78, 2007.

K. Yanaba, J. Bouaziz, K. M. Haas, J. C. Poe, M. Fujimoto et al., A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses, Immunity, vol.28, pp.639-50, 2008.

J. Bouaziz, K. Yanaba, and T. F. Tedder, Regulatory B cells as inhibitors of immune responses and inflammation, Immunol Rev, vol.224, pp.201-215, 2008.

M. Hagn and B. Jahrsdörfer, Why do human B cells secrete granzyme B? Insights into a novel B-cell differentiation pathway, Oncoimmunology, vol.1, pp.1368-75, 2012.
DOI : 10.4161/onci.22354
URL : https://www.tandfonline.com/doi/pdf/10.4161/onci.22354?needAccess=true

S. Fillatreau, C. H. Sweenie, M. J. Mcgeachy, D. Gray, and S. M. Anderton, B cells regulate autoimmunity by provision of IL-10, Nat Immunol, vol.3, pp.944-50, 2002.

C. Mauri, D. Gray, N. Mushtaq, and M. Londei, Prevention of arthritis by interleukin 10-producing B cells, J Exp Med, vol.197, pp.489-501, 2003.

V. Lampropoulou, K. Hoehlig, T. Roch, P. Neves, C. Gómez et al., TLR-activated B cells suppress T cell-mediated autoimmunity, J Immunol, vol.180, pp.4763-73, 2008.
URL : https://hal.archives-ouvertes.fr/pasteur-00324528

A. Yoshizaki, T. Miyagaki, D. J. Dilillo, T. Matsushita, M. Horikawa et al., Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions, Nature, vol.491, pp.264-272, 2012.

T. Matsushita, M. Horikawa, Y. Iwata, and T. F. Tedder, Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis, J Immunol, vol.185, pp.2240-52, 2010.

D. Maseda, S. H. Smith, D. J. Dilillo, J. M. Bryant, K. M. Candando et al., Regulatory B10 cells differentiate into antibody-secreting cells after transient IL-10 production in vivo, J Immunol, vol.188, pp.1036-1084, 2012.

R. Montandon, S. Korniotis, E. Layseca-espinosa, C. Gras, J. Mégret et al., Innate pro-B-cell progenitors protect against type 1 diabetes by regulating autoimmune effector T cells, Proc Natl Acad Sci U S A, vol.110, pp.2199-208, 2013.
URL : https://hal.archives-ouvertes.fr/hal-00845005

P. A. Blair, K. A. Chavez-rueda, J. G. Evans, M. J. Shlomchik, A. Eddaoudi et al., Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in MRL/lpr mice, J Immunol, vol.182, pp.3492-502, 2009.

T. Matsushita, K. Yanaba, J. Bouaziz, M. Fujimoto, and T. F. Tedder, Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression, J Clin Invest, vol.118, 2008.

N. A. Carter, R. Vasconcellos, E. C. Rosser, C. Tulone, A. Muñoz-suano et al., Mice lacking endogenous IL-10-producing regulatory B cells develop exacerbated disease and present with an increased frequency of Th1/Th17 but a decrease in regulatory T cells, J Immunol, vol.186, pp.5569-79, 2011.

M. K. Mann, K. Maresz, L. P. Shriver, Y. Tan, and B. N. Dittel, B cell regulation of CD4+CD25+ T regulatory cells and IL-10 via B7 is essential for recovery from experimental autoimmune encephalomyelitis, J Immunol, vol.178, pp.3447-56, 2007.

Y. Watanabe, T. Takahashi, A. Okajima, M. Shiokawa, N. Ishii et al., The analysis of the functions of human B and T cells in humanized NOD/shiscid/gammac(null) (NOG) mice (hu-HSC NOG mice), Int Immunol, vol.21, pp.843-58, 2009.

P. A. Blair, L. Y. Noreña, F. Flores-borja, D. J. Rawlings, D. A. Isenberg et al., CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients, Immunity, vol.32, pp.129-169, 2010.

S. Lemoine, A. Morva, P. Youinou, and C. Jamin, Human T cells induce their own regulation through activation of B cells, J Autoimmun, vol.36, pp.228-266, 2011.
URL : https://hal.archives-ouvertes.fr/hal-00771265

Y. Iwata, T. Matsushita, M. Horikawa, D. J. Dilillo, K. Yanaba et al., Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells, Blood, vol.117, pp.530-571, 2011.

A. Morva, S. Lemoine, A. Achour, J. Pers, P. Youinou et al., Maturation and function of human dendritic cells are regulated by B lymphocytes, Blood, vol.119, pp.106-120, 2012.
URL : https://hal.archives-ouvertes.fr/hal-00771106

D. C. Parker, D. L. Greiner, N. E. Phillips, M. C. Appel, A. W. Steele et al., Survival of mouse pancreatic isletallografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand, Proc Natl Acad Sci U S A, vol.92, pp.9560-9564, 1995.

M. Niimi, T. C. Pearson, C. P. Larsen, D. Z. Alexander, D. Hollenbaugh et al., The role of the CD40 pathway in alloantigen-induced hyporesponsiveness in vivo, J Immunol, vol.161, pp.5331-5338, 1998.

Y. Yan, K. Van-der-putten, D. G. Bowen, D. M. Painter, J. Kohar et al., Postoperative administration of donor B cells induces rat kidney allograft acceptance: lack of association with Th2 cytokine expression in long-term accepted grafts, Transplantation, vol.73, 2002.

S. Deng, D. J. Moore, X. Huang, M. Lian, M. Mohiuddin et al., Cutting edge: transplant tolerance induced by anti-CD45RB requires B lymphocytes, J Immunol, vol.178, pp.6028-6060, 2007.

X. Huang, D. J. Moore, M. Mohiuddin, M. Lian, J. I. Kim et al., Inhibition of ICAM-1/LFA-1 interactions prevents B-cell-dependent anti-CD45RB-induced transplantation tolerance, Transplantation, vol.85, pp.675-80, 2008.

G. Zhao, D. J. Moore, K. M. Lee, J. I. Kim, P. E. Duff et al., An unexpected counter-regulatory role of IL-10 in B-lymphocyte-mediated transplantation tolerance, Am J Transplant, vol.10, pp.796-801, 2010.

Q. Ding, M. Yeung, G. Camirand, Q. Zeng, H. Akiba et al., Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice, J Clin Invest, vol.121, pp.3645-56, 2011.

L. Texier, L. , T. P. Lavault, A. Usal, C. Merieau et al., Long-term allograft tolerance is characterized by the accumulation of B cells exhibiting an inhibited profile, Am J Transplant, vol.11, pp.429-467, 2011.

K. M. Lee, J. I. Kim, R. Stott, J. Soohoo, M. R. O'connor et al., Anti-CD45RB/anti-TIM-1-induced tolerance requires regulatory B cells, Am J Transplant, vol.12, pp.2072-78, 2012.

S. Louis, C. Braudeau, M. Giral, A. Dupont, F. Moizant et al., Contrasting CD25hiCD4+T cells/FOXP3 patterns in chronic rejection and operational drug-free tolerance, Transplantation, vol.81, pp.398-407, 2006.

S. Brouard, E. Mansfield, C. Braud, L. Li, M. Giral et al., Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance, Proc Natl Acad Sci U S A, vol.104, pp.15448-53, 2007.

A. Pallier, S. Hillion, R. Danger, M. Giral, M. Racapé et al., Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype, Kidney Int, vol.78, pp.503-516, 2010.

R. Danger, E. Thervet, M. Grisoni, P. L. Puig, A. Pallier et al., PARVG gene polymorphism and operational renal allograft tolerance, Transplant Proc, vol.44, pp.2845-2853, 2012.

H. M. Silva, M. Takenaka, P. Moraes-vieira, S. M. Monteiro, M. O. Hernandez et al., Preserving the B cell compartment favors operational tolerance in human renal transplantation, Mol Med, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01959589

L. D. Haynes, E. Jankowska-gan, A. Sheka, M. R. Keller, M. P. Hernandez-fuentes et al., Donor-specific indirect pathway analysis reveals a B-cellindependent signature which reflects outcomes in kidney transplant recipients, Am J Transplant, 2009.

M. Chesneau, A. Pallier, F. Braza, G. Lacombe, L. Gallou et al., Unique B cell differentiation profile in tolerant kidney transplant patients, Am J Transplant, 2013.
URL : https://hal.archives-ouvertes.fr/hal-00974748

G. A. Koretzky, J. Picus, T. Schultz, and A. Weiss, Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production, Proc Natl Acad Sci U S A, vol.88, pp.2037-2078, 1991.

D. J. Moore, X. Huang, M. K. Lee, . Iv, M. Lian et al., Resistance to anti-CD45RB-induced tolerance in NOD mice: mechanisms involved, Transpl Int, vol.17, pp.261-270, 2004.

G. J. Freeman, J. M. Casasnovas, D. T. Umetsu, and R. H. Dekruyff, TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity, Immunol Rev, vol.235, pp.172-89, 2010.

T. Ueno, A. Habicht, M. R. Clarkson, M. J. Albin, K. Yamaura et al., The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model, J Clin Invest, vol.118, pp.742-51, 2008.

Y. Aiba, T. Yamazaki, T. Okada, K. Gotoh, H. Sanjo et al., BANK negatively regulates Akt activation and subsequent B cell responses, Immunity, vol.24, pp.259-68, 2006.

S. V. Kozyrev, A. Abelson, J. Wojcik, A. Zaghlool, L. Reddy et al., Corrigendum: functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus, Nat Genet, vol.40, p.484, 2008.

T. L. Mcgaha, M. Karlsson, and J. V. Ravetch, FcgammaRIIB deficiency leads to autoimmunity and a defective response to apoptosis in Mrl-MpJ mice, J Immunol, vol.180, pp.5670-5679, 2008.

E. C. Lewis, M. Mizrahi, M. Toledano, N. Defelice, J. L. Wright et al., alpha1-Antitrypsin monotherapy induces immune tolerance during isletallograft transplantation in mice, Proc Natl Acad Sci U S A, vol.105, pp.16236-16277, 2008.
DOI : 10.1073/pnas.0807627105
URL : http://www.pnas.org/content/105/42/16236.full.pdf

G. Shahaf, H. Moser, E. Ozeri, M. Mizrahi, A. Abecassis et al., ?-1-Antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents isletallograft rejection, Mol Med, vol.17, pp.1000-1011, 2011.
DOI : 10.2119/molmed.2011.00145
URL : https://doi.org/10.2119/molmed.2011.00145

A. Nouël, I. Ségalen, C. Jamin, L. Doucet, S. Caillard et al., B cells display an abnormal distribution and an impaired suppressive function in patients with chronic antibody-mediated rejection, Kidney Int, 2013.

,

F. Porcheray, W. Wong, S. L. Saidman, D. Vito, J. Girouard et al., B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans, Am J Transplant, vol.9, pp.2126-2161, 2009.

G. Orlando, S. Soker, and K. Wood, Operational tolerance after liver transplantation, J Hepatol, vol.50, pp.1247-57, 2009.
DOI : 10.1016/j.jhep.2009.03.006

M. Martínez-llordella, I. Puig-pey, G. Orlando, M. Ramoni, G. Tisone et al., Multiparameter immune profiling of operational tolerance in liver transplantation, Am J Transplant, vol.7, pp.309-328, 2007.

J. J. Lozano, A. Pallier, M. Martinez-llordella, R. Danger, M. López et al., Comparison of transcriptional and blood cell-phenotypic markers between operationally tolerant liver and kidney recipients, Am J Transplant, vol.11, pp.1916-1942, 2011.

C. Jamin, A. Achour, P. Youinou, and J. Pers, Regulatory lymphocytes: a new cooperation between T and B cells for a better control of the immune response, Presse Med, 2013.
URL : https://hal.archives-ouvertes.fr/hal-00957388