X. Pan, H. Baldauf, O. T. Keppler, and O. T. Fackler, Restrictions to HIV-1 replication in resting CD4+ T lymphocytes, Cell Res, vol.23, issue.7, p.23732522, 2013.

L. A. Pereira, K. Bentley, A. Peeters, M. J. Churchill, and N. J. Deacon, A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter, Nucleic Acids Res, vol.28, issue.3, p.10637316, 2000.

J. K. Chan, D. Bhattacharyya, K. G. Lassen, D. Ruelas, and W. C. Greene, Calcium/calcineurin synergizes with prostratin to promote NF-?B dependent activation of latent HIV, PloS One, vol.8, issue.10, p.24204950, 2013.

T. Booiman, V. V. Loukachov, K. A. Van-dort, A. B. Van-'t-wout, and N. A. Kootstra, DYRK1A Controls HIV-1 Replication at a Transcriptional Level in an NFAT Dependent Manner, PloS One, vol.10, issue.12, p.26641855, 2015.

S. G. Deeks, S. R. Lewin, A. L. Ross, J. Ananworanich, M. Benkirane et al., International AIDS Society global scientific strategy: towards an HIV cure 2016, Nat Med, vol.22, issue.8, p.27400264, 2016.
DOI : 10.1038/nm.4108
URL : https://hal.archives-ouvertes.fr/hal-01355203

S. R. Jacobs, R. D. Michalek, and J. C. Rathmell, IL-7 Is Essential for Homeostatic Control of T Cell Metabolism In Vivo, J Immunol, vol.184, issue.7, p.20194717, 2010.

J. Sprent and C. D. Surh, Normal T cell homeostasis: the conversion of naïve cells into memory-phenotype cells, Nat Immunol, vol.12, issue.6, p.21739670, 2011.

E. Z. Managlia, A. Landay, and L. Al-harthi, Interleukin-7 induces HIV replication in primary naive T cells through a nuclear factor of activated T cell (NFAT)-dependent pathway, Virology, vol.350, issue.2, p.16542695, 2006.

D. Unutmaz, V. N. Kewalramani, S. Marmon, and D. R. Littman, Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes, J Exp Med, vol.189, issue.11, p.10359577, 1999.

M. Coiras, M. Bermejo, B. Descours, E. Mateos, J. García-pé-rez et al., IL-7 Induces SAMHD1 Phosphorylation in CD4+ T Lymphocytes, Improving Early Steps of HIV-1 Life Cycle. Cell Rep, vol.14, p.26923586, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01287804

H. Lahouassa, W. Daddacha, H. Hofmann, D. Ayinde, E. C. Logue et al., SAMHD1 restricts HIV-1 by reducing the intracellular pool of deoxynucleotide triphosphates, Nat Immunol, vol.13, issue.3, p.22327569, 2012.
DOI : 10.1038/ni.2236
URL : http://europepmc.org/articles/pmc3771401?pdf=render

B. Descours, A. Cribier, C. Chable-bessia, D. Ayinde, G. Rice et al., SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells, Retrovirology, vol.9, p.23092122, 2012.
DOI : 10.1186/1742-4690-9-87
URL : https://hal.archives-ouvertes.fr/pasteur-00750469

A. Cribier, B. Descours, A. Valadão, N. Laguette, and M. Benkirane, Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1. Cell Rep, vol.3, p.23602554, 2013.

S. Fabre, V. Lang, J. Harriague, A. Jobart, T. G. Unterman et al., Stable Activation of Phosphatidylinositol 3-Kinase in the T Cell Immunological Synapse Stimulates Akt Signaling to FoxO1 Nuclear Exclusion and Cell Growth Control, PMID: 15778376 FOXO1 controls HIV-1 latency in T cells PLOS Pathogens, vol.174, pp.4161-71, 2005.

B. Trinité, C. N. Chan, C. S. Lee, S. Mahajan, Y. Luo et al., Suppression of Foxo1 activity and down-modulation of CD62-L (L-selectin) in HIV-1 infected resting CD4 T cells, PloS One, vol.9, issue.10, p.25330112, 2014.

T. Nagashima, N. Shigematsu, R. Maruki, Y. Urano, H. Tanaka et al., Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice, Mol Pharmacol, vol.78, issue.5, p.20736318, 2010.

C. S. Palmer, C. L. Cherry, I. Sada-ovalle, A. Singh, and S. M. Crowe, Glucose Metabolism in T Cells and Monocytes: New Perspectives in HIV Pathogenesis, EBioMedicine, vol.6, p.27211546, 2016.
DOI : 10.1016/j.ebiom.2016.02.012
URL : https://doi.org/10.1016/j.ebiom.2016.02.012

M. Craveiro, I. Clerc, M. Sitbon, and N. Taylor, Metabolic pathways as regulators of HIV infection, Curr Opin HIV AIDS, vol.8, issue.3, p.23564003, 2013.
DOI : 10.1097/coh.0b013e32835fc53e

S. J. Khoury, C. R. Guttmann, E. J. Orav, R. Kikinis, F. A. Jolesz et al., Changes in activated T cells in the blood correlate with disease activity in multiple sclerosis, Arch Neurol, vol.57, issue.8, p.10927799, 2000.

M. Shipkova and E. Wieland, Surface markers of lymphocyte activation and markers of cell proliferation, Clin Chim Acta Int J Clin Chem, vol.413, pp.1338-1387, 2012.

J. Ablack, P. J. Metz, J. T. Chang, J. M. Cantor, and M. H. Ginsberg, Ubiquitylation of CD98 limits cell proliferation and clonal expansion, J Cell Sci, vol.128, issue.23, p.26493331, 2015.

J. Cantor, M. Slepak, N. Ege, J. T. Chang, and M. H. Ginsberg, Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity, J Immunol Baltim Md, vol.187, issue.2, pp.851-60, 1950.

D. W. Huang, B. T. Sherman, and R. A. Lempicki, Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists, Nucleic Acids Res, vol.37, issue.1, p.19033363, 2009.

D. W. Huang, B. T. Sherman, and R. A. Lempicki, Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources, Nat Protoc, vol.4, issue.1, p.19131956, 2009.

S. Fabre, F. Carrette, J. Chen, V. Lang, M. Semichon et al., FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase, J Immunol Baltim Md, vol.181, issue.5, pp.2980-2989, 1950.
URL : https://hal.archives-ouvertes.fr/inserm-00326137

M. Y. Jeng, P. A. Hull, M. Fei, H. Kwon, C. Tsou et al., Metabolic reprogramming of human CD8+ memory T cells through loss of SIRT1, J Exp Med, 2017.

M. J. Scheffel, G. Scurti, M. M. Wyatt, E. Garrett-mayer, C. M. Paulos et al., N-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner, Cancer Immunol Immunother CII, vol.67, issue.4, p.29396710, 2018.

N. J. Maciver, R. D. Michalek, and J. C. Rathmell, Metabolic Regulation of T Lymphocytes, Annu Rev Immunol, vol.31, p.23298210, 2013.

Y. Fan, S. Sanyal, and R. Bruzzone, Breaking Bad: How Viruses Subvert the Cell Cycle, Front Cell Infect Microbiol, vol.8, p.30510918, 2018.

A. Jordan, D. Bisgrove, and E. Verdin, HIV reproducibly establishes a latent infection after acute infection of T cells in vitro, EMBO J, vol.15, issue.8, p.12682019, 2003.

A. Brunet, A. Bonni, M. J. Zigmond, M. Z. Lin, P. Juo et al., Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor, Cell, vol.96, issue.6, p.10102273, 1999.

A. Bosque and V. Planelles, Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells, Blood, vol.113, issue.1, p.18849485, 2009.

P. Mlcochova, K. A. Sutherland, S. A. Watters, C. Bertoli, R. A. De-bruin et al., A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages, EMBO J, vol.36, issue.5, p.28122869, 2017.

R. P. Fisher, Getting to S: CDK functions and targets on the path to cell-cycle commitment, 1000.

T. H. Cheung and T. A. Rando, Molecular regulation of stem cell quiescence, Nat Rev Mol Cell Biol, vol.14, issue.6, p.23698583, 2013.
DOI : 10.1038/nrm3591
URL : http://europepmc.org/articles/pmc3808888?pdf=render

A. B. Pardee, A Restriction Point for Control of Normal Animal Cell Proliferation, PMID: 4524638 FOXO1 controls HIV-1 latency in T cells PLOS Pathogens, vol.71, pp.1286-90, 1974.

P. M. Gubser, G. R. Bantug, L. Razik, M. Fischer, S. Dimeloe et al., Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch, Nat Immunol, vol.14, issue.10, p.23955661, 2013.

A. Allam, D. B. Conze, G. Torchia, M. L. Munitic, I. Yagita et al., The CD8+ memory Tcell state of readiness is actively maintained and reversible, Blood, vol.114, issue.10, p.19617575, 2009.

J. Froehlich, M. Versapuech, L. Megrelis, Q. Largeteau, S. Meunier et al., FAM65B controls the proliferation of transformed and primary T cells, Oncotarget, vol.7, issue.39, p.27556504, 2016.
URL : https://hal.archives-ouvertes.fr/inserm-01361856

J. T. Barata, A. Silva, J. G. Brandao, L. M. Nadler, A. A. Cardoso et al., Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells, J Exp Med, vol.200, issue.5, p.15353558, 2004.

J. C. Valle-casuso, M. Angin, S. Volant, C. Passaes, V. Monceaux et al., Cellular Metabolism Is a Major Determinant of HIV-1 Reservoir Seeding in CD4+ T Cells and Offers an Opportunity to Tackle Infection, Cell Metab, 2018.
URL : https://hal.archives-ouvertes.fr/pasteur-02017878

A. Oteiza and N. Mechti, FoxO4 negatively controls Tat-mediated HIV-1 transcription through the post-transcriptional suppression of Tat encoding mRNA, J Gen Virol, vol.98, issue.7, p.28699853, 2017.

A. Gudlur and P. G. Hogan, The STIM-Orai Pathway: Orai, the Pore-Forming Subunit of the CRAC Channel, Adv Exp Med Biol, vol.993, p.28900908, 2017.

P. Zou, L. Liu, L. Zheng, L. Liu, R. E. Stoneman et al., Targeting FoxO1 with AS1842856 suppresses adipogenesis, Cell Cycle, vol.13, issue.23, p.25483084, 2014.
DOI : 10.4161/15384101.2014.965977
URL : http://europepmc.org/articles/pmc4613185?pdf=render

L. Zhang, Q. H. Ji, F. Ruge, C. Lane, D. Morris et al., Reversal of Pathological Features of Graves' Orbitopathy by Activation of Forkhead Transcription Factors, FOXOs, J Clin Endocrinol Metab, 2016.

, , vol.101, p.26502358

P. Tan, H. Guan, L. Xie, M. B. Fang, Z. Li et al., FOXO1 inhibits osteoclastogenesis partially by antagnozing MYC. Sci Rep, vol.5, p.16835, 2015.

S. Chung, T. J. Lee, B. F. Reader, J. Y. Kim, Y. G. Lee et al., FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype, Oncotarget

, Apr, vol.5, issue.14, p.27007158

R. B. Jones and B. D. Walker, HIV-specific CD8
URL : https://hal.archives-ouvertes.fr/hal-01595823

+. , J Clin Invest, vol.126, issue.2, p.26731469, 2016.

C. Randriamampita, G. Boulla, P. Revy, F. Lemaitre, and A. Trautmann, T cell adhesion lowers the threshold for antigen detection, Eur J Immunol, vol.33, issue.5, p.12731046, 2003.

L. Casetti, S. Martin-lannerée, I. Najjar, I. Plo, S. Augé et al., Differential contributions of STAT5A and STAT5B to stress protection and tyrosine kinase inhibitor resistance of chronic myeloid leukemia stem/progenitor cells, Cancer Res, vol.73, issue.7, p.23400594, 2013.

L. Bracq, M. Xie, M. Lambelé, L. Vu, J. Matz et al., T cell-macrophage fusion triggers multinucleated giant cell formation for HIV-1 spreading, J Virol, 2017.
DOI : 10.1128/jvi.01237-17
URL : https://jvi.asm.org/content/jvi/91/24/e01237-17.full.pdf

G. Q. Del-prete, J. Smedley, R. Macallister, G. S. Jones, B. Li et al., Short Communication: Comparative Evaluation of Coformulated Injectable Combination Antiretroviral Therapy Regimens in Simian Immunodeficiency Virus-Infected Rhesus Macaques, AIDS Res Hum Retroviruses, 2016.

, , vol.32, p.26150024

G. Matusali, N. Dereuddre-bosquet, L. Tortorec, A. Moreau, M. Satie et al., Detection of Simian Immunodeficiency Virus in Semen, Urethra, and Male Reproductive Organs during Efficient Highly Active Antiretroviral Therapy, J Virol, vol.89, issue.11, p.25833047, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01139816

R. Ponte, M. Rancez, S. Figueiredo-morgado, J. Dutrieux, V. Fabre-mersseman et al., Acute Simian Immunodeficiency Virus Infection Triggers Early and Transient Interleukin-7 Production in the Gut, Leading to Enhanced Local Chemokine Expression and Intestinal Immune Cell Homing, Front Immunol, vol.8, p.28579989, 2017.
URL : https://hal.archives-ouvertes.fr/inserm-01568732