Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus, Nature, vol.478, issue.7367, pp.97-111, 2011. ,
URL : https://hal.archives-ouvertes.fr/inserm-00619240
A copy number variation morbidity map of developmental delay, Nature Genetics, vol.43, issue.9, pp.838-882, 2011. ,
Association between microdeletion and microduplication at 16p11.2 and autism, New England Journal of Medicine, vol.358, issue.7, pp.667-75, 2008. ,
Structural variation of chromosomes in autism spectrum disorder, American Journal of Human Genetics, vol.82, issue.2, pp.477-88, 2008. ,
Phenotypic spectrum associated with de novo and inherited deletions and duplications at 16p11.2 in individuals ascertained for diagnosis of autism spectrum disorder, Journal of Medical Genetics, vol.47, issue.3, pp.195-203, 2010. ,
Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism. Neuron, vol.70, issue.5, pp.863-85, 2011. ,
The cognitive and behavioral phenotype of the 16p11.2 deletion in a clinically ascertained population, Biol Psychiatry, vol.77, issue.9, p.25064419, 2015. ,
Abnormal auditory and language pathways in children with 16p11.2 deletion, Neuroimage Clin, vol.9, p.4543079, 2015. ,
A 600 kb deletion syndrome at 16p11.2 leads to energy imbalance and neuropsychiatric disorders, J Med Genet, vol.49, issue.10, p.3494011, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-01120401
A novel microdeletion at 16p11.2 harbors candidate genes for aortic valve development, seizure disorder, and mild mental retardation, American Journal of Medical Genetics Part A, vol.143, issue.13, pp.1462-71, 2007. ,
Recurrent reciprocal 16p11.2 rearrangements associated with global developmental delay, behavioural problems, dysmorphism, epilepsy, and abnormal head size, Journal of Medical Genetics, vol.47, issue.5, pp.332-373, 2010. ,
A 600 kb deletion syndrome at 16p11.2 leads to energy imbalance and neuropsychiatric disorders, Journal of Medical Genetics, vol.49, issue.10, pp.660-668, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-01120401
2 600 kb Duplications confer risk for typical and atypical Rolandic epilepsy, Hum Mol Genet, 2014. ,
Microduplications of 16p11.2 are associated with schizophrenia, Nature Genetics, vol.41, issue.11, 2009. ,
Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder, Molecular Psychiatry, vol.17, issue.9, pp.880-886, 2012. ,
Common variant at 16p11.2 conferring risk of psychosis, Molecular Psychiatry, vol.19, issue.1, pp.108-122, 2014. ,
A new highly penetrant form of obesity due to deletions on chromosome 16p11.2, Nature, vol.463, issue.7281, pp.671-104, 2010. ,
rare chromosomal deletions associated with severe early-onset obesity, Nature, vol.463, issue.7281, p.3108883, 2010. ,
The 16p11.2 locus modulates brain structures common to autism, schizophrenia and obesity, Mol Psychiatry, vol.20, issue.1, p.4320286, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01870357
A potential contributory role for ciliary dysfunction in the 16p11.2 600kb BP4-BP5 pathology, Am J Hum Genet, 2015. ,
Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism, Proceedings of the National Academy of Sciences of the United States of America, vol.108, issue.41, pp.17076-81, 2011. ,
Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome, Cell Rep, vol.7, issue.4, pp.1077-92, 2014. ,
Genetic background determines metabolic phenotypes in the mouse, Mamm Genome, vol.19, issue.5, pp.318-349, 2008. ,
URL : https://hal.archives-ouvertes.fr/inserm-00311085
Sighted C3H" mice-a tool for analysing the influence of vision on mouse behaviour?, Front Biosci, vol.13, p.18508624, 2008. ,
Object recognition memory and the rodent hippocampus, Learn Mem, vol.17, issue.1, p.2807177, 2010. ,
Sustained dorsal hippocampal activity is not obligatory for either the maintenance or retrieval of long-term spatial memory, Hippocampus, vol.20, issue.12, p.3072238, 2010. ,
Recognition memory and the medial temporal lobe: a new perspective, Nat Rev Neurosci, vol.8, issue.11, p.2323975, 2007. ,
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus, Nature, vol.478, issue.7367, p.3637175, 2011. ,
URL : https://hal.archives-ouvertes.fr/inserm-00619240
Euclidean distance matrix analysis: confidence intervals for form and growth differences, Am J Phys Anthropol, vol.98, issue.1, pp.73-86, 1995. ,
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository, Nucleic Acids Res, vol.30, issue.1, p.99122, 2002. ,
Genome-wide atlas of gene expression in the adult mouse brain, Nature, vol.445, issue.7124, p.17151600, 2007. ,
A gene transcription signature of the Akt/mTOR pathway in clinical breast tumors. Oncogene, vol.26, pp.4648-55, 2007. ,
Regulation of gene expression and cocaine reward by CREB and DeltaFosB, Nat Neurosci, vol.6, issue.11, pp.1208-1223, 2003. ,
Identification of genes involved in resistance to interferon-alpha in cutaneous T-cell lymphoma, Am J Pathol, vol.161, issue.5, p.1850769, 2002. ,
Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes, Mol Cell Biol, vol.27, issue.21, p.2169050, 2007. ,
A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors, Oncogene, vol.26, issue.27, p.17325667, 2007. ,
PID: the Pathway Interaction Database, Nucleic Acids Res, vol.37, p.2686461, 2009. ,
Activity-dependent regulation of inhibitory synapse development by Npas4, Nature, vol.455, issue.7217, p.2637532, 2008. ,
Antidepressant actions of the exercise-regulated gene VGF, Nat Med, vol.13, issue.12, pp.1476-82, 2007. ,
A module of negative feedback regulators defines growth factor signaling, Nat Genet, vol.39, issue.4, pp.503-515, 2007. ,
Propagation of adipogenic signals through an epigenomic transition state, Genes Dev, vol.24, issue.10, p.2867208, 2010. ,
Microarray analysis of gene expression during early adipocyte differentiation, Gene, vol.293, issue.1-2, 2002. ,
Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes, Mol Cell Biol, vol.28, issue.1, p.2223282, 2008. ,
Hnf1alpha (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver, Mol Cell Biol, vol.29, issue.11, pp.2945-59, 2009. ,
, , p.2682018
Kruppel-like factor KLF10 is a link between the circadian clock and metabolism in liver, Mol Cell Biol, vol.30, issue.12, p.2876690, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-00497185
Mouse behavioral assays relevant to the symptoms of autism, Brain Pathology, vol.17, issue.4, pp.448-59, 2007. ,
Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion, Nat Neurosci, vol.18, issue.2, p.4323380, 2015. ,
Copy number variation in bipolar disorder, Mol Psychiatry, 2015. ,
De novo CNVs in bipolar affective disorder and schizophrenia, Hum Mol Genet, vol.23, issue.24, p.4240207, 2014. ,
The number of genomic copies at the 16p11.2 locus modulates language, verbal memory and inhibition. Biol Psychiatry ,
Deletion of the AppRunx1 region in mice models human partial monosomy 21, Dis Model Mech, vol.8, issue.6, p.4457029, 2015. ,
Genetic background modulates phenotypes of serotonin transporter Ala56 knock-in mice, Mol Autism, vol.4, issue.1, p.3851031, 2013. ,
Genetic-background modulation of core and variable autistic-like symptoms in Fmr1 knock-out mice, PLoS One, vol.6, issue.2, p.3043074, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00908076
2 locus modulates response to satiety before the onset of obesity, Int J Obes ,
The expression of adipogenic genes is decreased in obesity and diabetes mellitus, Proc Natl Acad Sci, vol.97, issue.21, p.17207, 2000. ,
Gene expression profile of adipocyte differentiation and its regulation by peroxisome proliferator-activated receptor-gamma agonists, Endocrinology, vol.143, issue.6, pp.2106-2124, 2002. ,
Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect, J Clin Invest, vol.99, issue.4, p.507838, 1997. ,
Molecular targets of a human HNF1 alpha mutation responsible for pancreatic beta-cell dysfunction, EMBO J, vol.19, issue.16, p.302029, 2000. ,
Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism, Nat Genet, vol.27, issue.4, pp.375-82, 2001. ,
Evidence for a voltage-dependent enhancement of neurotransmitter release mediated via the synaptic protein interaction site of N-type Ca2+ channels, Proc Natl Acad Sci U S A, vol.95, issue.24, p.24406, 1998. ,
Doc2alpha is an activity-dependent modulator of excitatory synaptic transmission, Eur J Neurosci, vol.11, issue.12, p.10594652, 1999. ,
A tumor necrosis factor alpha-and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen, Proc Natl Acad Sci U S A, vol.98, issue.21, p.11593007, 2001. ,
, , p.59753
KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant, Nature, vol.485, issue.7398, p.3366115, 2012. ,
SRPX2 mutations in disorders of language cortex and cognition, Hum Mol Genet, vol.15, issue.7, pp.1195-207, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-00089725
Variations of the candidate SEZ6L2 gene on Chromosome 16p11.2 in patients with autism spectrum disorders and in human populations, PLoS One, vol.6, issue.3, p.3048866, 2011. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01967143
Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex, Nat Neurosci, vol.15, issue.7, p.4017029, 2012. ,
Applying the ARRIVE Guidelines to an In Vivo Database, PLoS Biol, vol.13, issue.5, p.4439173, 2015. ,
Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research, PLoS Biol, vol.8, issue.6, p.2893951, 2010. ,
Nociceptin receptor impairs recognition memory via interaction with NMDA receptor-dependent mitogen-activated protein kinase/ extracellular signal-regulated kinase signaling in the hippocampus, J Neurosci, vol.28, issue.9, pp.2190-2198, 2008. ,
URL : https://hal.archives-ouvertes.fr/hal-00282572
Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine, Biol Psychiatry, vol.69, issue.3, pp.236-280, 2011. ,
The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome, Behavioural Brain Research, vol.217, issue.2, pp.271-81, 2011. ,
TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function, J Neurosci, vol.32, issue.40, p.3978779, 2012. ,
Recording long-term potentiation of synaptic transmission by three-dimensional multi-electrode arrays, BMC Neurosci, vol.7, p.1574331, 2006. ,
Linear models and empirical bayes methods for assessing differential expression in microarray experiments, Stat Appl Genet Mol Biol, vol.3, p.3, 2004. ,
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles, Proc Natl Acad Sci U S A, vol.102, issue.43, p.1239896, 2005. ,
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes, Nat Genet, vol.34, issue.3, pp.267-73, 2003. ,