How Tets and Cytoskeleton Dynamics MET in Reprogramming

Laurent David 1, 2, 3, * Calley Hirsch 4
* Corresponding author
3 CHU Nantes/INSERM/CNRS-IFR Santé François Bonamy - Plate-forme Cellules souches pluripotentes induites - iPSC [Nantes]
SFR RSFB - Structure Fédérative de Recherche en Santé François Bonamy, CHU Nantes - Centre hospitalier universitaire de Nantes, INSERM - Institut National de la Santé et de la Recherche Médicale, CNRS - Centre National de la Recherche Scientifique, UN - Université de Nantes
Abstract : Two studies by Sakurai et al. (2014) and Hu et al. (2014) in this issue of Cell Stem Cell add a new level of understanding to the mesenchymal-to-epithelial transition taking place during reprogramming, showing how this morphological transformation is promoted by Tet enzymes and blocked by kinase-dependent cytoskeletal organization.
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Laurent David, Calley Hirsch. How Tets and Cytoskeleton Dynamics MET in Reprogramming. Cell Stem Cell, Cambridge, MA : Cell Press, 2014, 14. ⟨inserm-02163611⟩

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