Transplantation -a medical miracle of the 20th century, N Engl J Med, vol.351, pp.2678-2680, 2004. ,
Diagnosis and prevention of chronic kidney allograft loss, Lancet, vol.378, pp.1428-1437, 2011. ,
Effect of long-term immunosuppression in kidney-graft recipients on cancer incidence: randomised comparison of two cyclosporin regimens, Lancet, vol.351, pp.623-628, 1998. ,
Immunosuppressive drugs for kidney transplantation, N Engl J Med, vol.351, pp.2715-2729, 2004. ,
The natural history of chronic allograft nephropathy, N Engl J Med, vol.349, pp.2326-2333, 2003. ,
Strategies to improve long-term outcomes after renal transplantation, N Engl J Med, vol.346, pp.580-590, 2002. ,
05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN'), Am J Transplant, vol.7, pp.518-526, 2007. ,
Controlling the incidence of infection and malignancy by modifying immunosuppression, Transplantation, vol.72, pp.89-93, 2001. ,
In search of the elusive Holy Grail: the mechanisms and prospects for achieving clinical transplantation tolerance, Am J Transplant, vol.1, pp.6-12, 2001. ,
Actively acquired tolerance of foreign cells, Nature, vol.172, pp.603-606, 1953. ,
Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease, Immunol Rev, vol.212, pp.8-27, 2006. ,
Regulatory T cells in transplantation tolerance, Nat Rev Immunol, vol.3, pp.199-210, 2003. ,
Transfer of tolerance to heart and kidney allografts in the rat model, Transpl Int, vol.21, pp.199-206, 2008. ,
Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts, Nature, vol.307, pp.168-170, 1984. ,
Mixed allogeneic chimerism as an approach to transplantation tolerance, Immunol Today, vol.9, pp.23-27, 1988. ,
Is clinical tolerance realistic in the next decade?, Transpl Int, vol.19, pp.539-548, 2006. ,
Belatacept-based regimens versus a cyclosporine A-based regimen in kidney transplant recipients: 2-year results from the BENEFIT and BENEFIT-EXT studies, Transplantation, vol.90, pp.1528-1535, 2010. ,
Costimulatory pathways in transplantation, Semin Immunol, vol.23, pp.293-303, 2011. ,
Infection in solid-organ transplant recipients, N Engl J Med, vol.357, pp.2601-2614, 2007. ,
Prednisone withdrawal late after adult liver transplantation reduces diabetes, hypertension, and hypercholesterolemia without causing graft loss, Hepatology, vol.25, pp.173-177, 1997. ,
Humoral and cellular responses to influenza vaccination in human recipients naturally tolerant to a kidney allograft, Am J Transplant, vol.6, pp.2796-2801, 2006. ,
The natural history of clinical operational tolerance after kidney transplantation through twenty-seven cases, Am J Transplant, vol.12, pp.3296-3307, 2012. ,
Clinical operational tolerance after kidney transplantation, Am J Transplant, vol.6, pp.736-746, 2006. ,
Spontaneous operational tolerance after immunosuppressive drug withdrawal in clinical renal allotransplantation, Transplantation, vol.84, pp.1215-1219, 2007. ,
An appraisal of tolerance in liver transplantation, Am J Transplant, vol.6, pp.1774-1780, 2006. ,
Towards the identification of biomarkers of transplantation tolerance, Nat Rev Immunol, vol.9, pp.521-526, 2009. ,
Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient, Transplantation, vol.59, pp.1147-1155, 1995. ,
Indications of immunological tolerance in kidney transplantation, Tissue Antigens, vol.51, pp.637-644, 1998. ,
Specific immune tolerance during pregnancy after renal transplantation, Eur J Obstet Gynecol Reprod Biol, vol.70, pp.217-219, 1996. ,
Cessation of immunosuppression after renal transplantation, Surgery, vol.79, pp.278-282, 1976. ,
Cessation of immunosuppressive therapy after successful transplantation: a national survey, Kidney Int, vol.18, pp.110-114, 1980. ,
Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance, Proc Natl Acad Sci, vol.104, pp.15448-15453, 2007. ,
Donor-specific indirect pathway analysis reveals a B-cell-independent signature which reflects outcomes in kidney transplant recipients, Am J Transplant, vol.12, pp.640-648, 2012. ,
Identification of a B cell signature associated with renal transplant tolerance in humans, J Clin Invest, vol.120, pp.1836-1847, 2010. ,
Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype, Kidney Int, vol.78, pp.503-513, 2010. ,
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans, J Clin Invest, vol.120, pp.1848-1861, 2010. ,
Biomarkers and surrogate endpoints: preferred definitions and conceptual framework, Clin Pharmacol Ther, vol.69, pp.89-95, 2001. ,
meeting report: new concepts in antibody-mediated rejection, Am J Transplant, vol.12, pp.563-570, 2011. ,
09 meeting report: antibody mediated graft deterioration and implementation of Banff working groups, Am J Transplant, vol.10, pp.464-471, 2010. ,
Using biomarkers of tolerance and rejection to identify high-and low-risk patients following kidney transplantation, Transplantation, vol.87, pp.95-99, 2009. ,
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling, Nature, vol.403, pp.503-511, 2000. ,
Proteomic profiling of acute cardiac allograft rejection, Transplantation, vol.88, pp.553-560, 2009. ,
Molecular diagnostics in transplantation, Nat Rev Nephrol, vol.6, pp.614-628, 2010. ,
Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells, PLoS ONE, vol.5, p.10192, 2010. ,
Transplantation: integrative peptidomics identifies acute renal-transplant rejection biomarkers, Nat Rev Nephrol, vol.6, p.249, 2010. ,
Identification of highly responsive kidney transplant recipients using pretransplant soluble CD30, J Am Soc Nephrol, vol.13, pp.1650-1656, 2002. ,
Variation in numbers of CD4+CD25highFOXP3+ T cells with normal immuno-regulatory properties in long-term graft outcome, Transpl Int, vol.20, pp.845-855, 2007. ,
Cellular infiltrates and NFjB subunit c-Rel signaling in kidney allografts of patients with clinical operational tolerance, Transplantation, vol.94, pp.729-737, 2012. ,
Regulatory, effector, and cytotoxic T cell profiles in long-term kidney transplant patients, J Am Soc Nephrol, vol.20, pp.1113-1122, 2009. ,
Evaluation of gene panel mRNAs in urine samples of kidney transplant recipients as a non-invasive tool of graft function, Mol Med, vol.13, pp.315-324, 2007. ,
Messenger RNA for FOXP3 in the urine of renal-allograft recipients, N Engl J Med, vol.353, pp.2342-2351, 2005. ,
Human allograft acceptance is associated with immune regulation, J Clin Invest, vol.106, pp.145-155, 2000. ,
Operationally tolerant and minimally immunosuppressed kidney recipients display strongly altered blood T-cell clonal regulation, Am J Transplant, vol.5, pp.330-340, 2005. ,
Contrasting CD25hiCD4+T cells/ FOXP3 patterns in chronic rejection and operational drug-free tolerance, Transplantation, vol.81, pp.398-407, 2006. ,
Phenotypically and functionally distinct CD8+ lymphocyte populations in long-term drug-free tolerance and chronic rejection in human kidney graft recipients, J Am Soc Nephrol, vol.17, pp.294-304, 2006. ,
Immunosuppressive drug-free operational immune tolerance in human kidney transplant recipients: Part I. Blood gene expression statistical analysis, J Cell Biochem, vol.103, pp.1681-1692, 2008. ,
Contrasted blood and intragraft toll-like receptor 4 mRNA profiles in operational tolerance versus chronic rejection in kidney transplant recipients, Transplantation, vol.86, pp.130-136, 2008. ,
Differential monocyte STAT6 activation and CD4(+)CD25(+)Foxp3(+) T cells in kidney operational tolerance transplanted individuals, Hum Immunol, vol.71, pp.442-450, 2010. ,
Comparison of transcriptional and blood cell-phenotypic markers between operationally tolerant liver and kidney recipients, Am J Transplant, vol.11, pp.1916-1926, 2011. ,
PARVG gene polymorphism and operational renal allograft tolerance, Transplant Proc, vol.44, pp.2845-2848, 2012. ,
GATA3 and a dominant regulatory gene expression profile discriminate operational tolerance in human transplantation, Clin Immunol, vol.142, pp.117-126, 2012. ,
Preserving the B cell compartment favors operational tolerance in human renal transplantation, Mol Med, vol.18, pp.733-743, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-01959589
Upregulation of miR-142-3p in peripheral blood mononuclear cells of operationally tolerant patients with a renal transplant, J Am Soc Nephrol, vol.23, pp.597-606, 2012. ,
Operational tolerance in kidney transplantation-improved terminology may enable more precise investigation, Transplantation, vol.96, pp.36-38, 2013. ,
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis, Nature, vol.389, pp.737-742, 1997. ,
Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering, Proc Natl Acad Sci, vol.89, pp.421-425, 1992. ,
Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells, J Exp Med, vol.196, pp.1335-1346, 2002. ,
Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor, Immunity, vol.30, pp.899-911, 2009. ,
Regulatory T cells and transplantation tolerance, Immunotherapy, vol.5, pp.717-731, 2013. ,
Transplantation tolerance: lessons from experimental rodent models, Transpl Int, vol.20, pp.828-841, 2007. ,
Enrichment of regulatory T cells in acutely rejected human liver allografts, Am J Transplant, vol.12, pp.3425-3436, 2012. ,
MHC class II expression identifies functionally distinct human regulatory T cells, J Immunol, vol.176, pp.4622-4631, 2006. ,
Delayed-type hypersensitivity and allograft rejection in the mouse: correlation of effector cell phenotype, Immunology, vol.46, pp.313-320, 1982. ,
B-1 B cells mediate required early T cell recruitment to elicit protein-induced delayed-type hypersensitivity, J Immunol, vol.171, pp.6225-6235, 2003. ,
T cells reactive to a single immunodominant self-restricted allopeptide induce skin graft rejection in mice, J Clin Invest, vol.101, pp.1398-1407, 1998. ,
CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase, J Clin Invest, vol.117, pp.1096-1106, 2007. ,
Mechanism and localization of CD8 regulatory T cells in a heart transplant model of tolerance, J Immunol, vol.185, pp.823-833, 2010. ,
Fc gamma RIIB activation leads to inhibition of signalling by independently ligated receptors, Biochem Soc Trans, vol.31, pp.281-285, 2003. ,
BANK negatively regulates Akt activation and subsequent B cell responses, Immunity, vol.24, pp.259-268, 2006. ,
Long-term allograft tolerance is characterized by the accumulation of B cells exhibiting an inhibited profile, Am J Transplant, vol.11, pp.429-438, 2011. ,
T cell-dependent B cell activation, Annu Rev Immunol, vol.11, pp.331-360, 1993. ,
Role of B lymphocytes in cell-mediated immunity. I. Requirement for T cells or T-cell products for antigen-induced B-cell activation, J Exp Med, vol.144, pp.1175-1187, 1976. ,
miR-142-3p restricts cAMP production in CD4+CD25-T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA, EMBO Rep, vol.10, pp.180-185, 2009. ,
Mechanisms of rejection: current perspectives, Transplantation, vol.93, pp.1-10, 2012. ,
A common peripheral blood gene set for diagnosis of operational tolerance in pediatric and adult liver transplantation, Am J Transplant, vol.12, pp.1218-1228, 2012. ,
Multiparameter immune profiling of operational tolerance in liver transplantation, Am J Transplant, vol.7, pp.309-319, 2007. ,
The peripheral NK cell repertoire after kidney transplantation is modulated by different immunosuppressive drugs, Front Immunol, vol.4, p.46, 2013. ,
Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity, Biochem Pharmacol, vol.72, pp.1102-1113, 2006. ,
Absence of MyD88 signaling induces donor-specific kidney allograft tolerance, J Am Soc Nephrol, vol.23, pp.1701-1716, 2012. ,
Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation, Sci Transl Med, vol.2, pp.17-27, 2010. ,
B cell repopulation after alemtuzumab induction-transient increase in transitional B cells and long-term dominance of na? ?ve B cells, Am J Transplant, vol.12, pp.1784-1792, 2012. ,
B lymphocyte-directed immunotherapy promotes long-term islet allograft survival in nonhuman primates, Nat Med, vol.13, pp.1295-1298, 2007. ,
Regulatory T cells and T cell depletion: role of immunosuppressive drugs, J Am Soc Nephrol, vol.18, pp.1007-1018, 2007. ,
B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans, Am J Transplant, vol.9, pp.2126-2135, 2009. ,