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Poster communications

Generation of Regulatory T Cells from Human Pluripotent Stem Cells

Léa Flippe 1, 2, 3 A. Gaignerie 4 S. Bezie 1, 2, 3 Ignacio Anegon 1, 2, 3 L. David 1, 2, 4 C. Guillonneau 1, 2, 3
1 U1064 Inserm - CRTI - Centre de Recherche en Transplantation et Immunologie
2 ITUN - Institut de transplantation urologie-néphrologie
3 LabEx IGO “Immunotherapy, Graft, Oncology” [Nantes]
4 SFR François Bonamy - Structure fédérative de recherche François Bonamy
Abstract : Organ or cell transplantation is the only therapeutic solution for pathologies causing an irreversible loss of vital organs function. The development of novel specific and non-toxic ani-rejection immunotherapies is a major goal in transplantation. Strategies based on Tregs are promising. However, Tregs cellbased therapies have been hampered by the technical limitation of obtaining large batches of functional Tregs. The project aim is to obtain an unlimited number of Tregs from human pluripotent stem cells. This very innovative project will also allow us to beter understand the development biology of Tregs through their in vitro differentiation.
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Poster communications
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https://www.hal.inserm.fr/inserm-02159833
Contributor : Sylvie Le Bihan <>
Submitted on : Wednesday, June 19, 2019 - 9:29:03 AM
Last modification on : Friday, November 15, 2019 - 8:44:09 AM

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  • HAL Id : inserm-02159833, version 1

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CNRS | UNIV-NANTES | CRTI

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Léa Flippe, A. Gaignerie, S. Bezie, Ignacio Anegon, L. David, et al.. Generation of Regulatory T Cells from Human Pluripotent Stem Cells. FOCIS 2019, Jun 2019, Boston, United States. ⟨inserm-02159833⟩

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