21st Nantes Actualités Transplantation: "When Stem Cells Meet Immunology"

Abstract : "When Stem Cells Meet Immunology" has been the topic of the 21st annual "Nantes Actualités en Transplantation" meeting (June 9-10, 2016, Nantes, France). This meeting brought together pioneers and leading experts in the fields of stem cells, biomaterials and immunoregulation. Presentations covered multipotent (mesenchymal and hematopoietic) and pluripotent stem cells (embryonic and induced) for regenerative medicine of incurable diseases, immunotherapy and blood transfusions. An additional focus had been immune rejections and responses of allogeneic or autologous stem cells. Conversely, stem cells are also able to directly modulate the immune response through the production of immunoregulatory molecules. Moreover, stem cells may also provide an unlimited source of immune cells (DCs, NK cells, B cells, and T cells) that can operate as "super" immune cells, for example, through genetic engineering with chimeric antigen receptors.This meeting report puts presentations into an overall context highlighting new potential biomarkers for potency prediction of mesenchymal stem cell-derived and pluripotent stem cell-derived multicellular organoids. Finally, we propose future directions arising from the flourishing encounter of stem cell and immune biology.
Document type :
Journal articles
Complete list of metadatas

Cited literature [75 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-02156087
Contributor : Ana Paula Dutra Azevedo <>
Submitted on : Friday, June 14, 2019 - 10:21:23 AM
Last modification on : Saturday, June 15, 2019 - 1:27:31 AM

File

 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document

Identifiers

Collections

Citation

Ignacio Anegon, Tuan Huy Nguyen. 21st Nantes Actualités Transplantation: "When Stem Cells Meet Immunology". Transplantation, Lippincott, Williams & Wilkins, 2017, 101 (1), pp.12-16. ⟨10.1097/TP.0000000000001476⟩. ⟨inserm-02156087⟩

Share

Metrics

Record views

56