Successful correction of hemophilia by CRISPR/Cas9 genome editing in vivo : delivery vector and immune responses are the key to success

Tuan Huy Nguyen; Ignacio Anegon

doi:10.15252/emmm.201606325

Journal Articles EMBO Molecular Medicine Year : 2016

Successful correction of hemophilia by CRISPR/Cas9 genome editing in vivo : delivery vector and immune responses are the key to success

(1, 2, 3) , (1, 2, 3)

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Tuan Huy Nguyen

Function : Author

Centre de Recherche en Transplantation et Immunologie

Institut de transplantation urologie-néphrologie

Faculté de Médecine - Université de Nantes

Ignacio Anegon

Function : Correspondent author
PersonId : 999262

Connectez-vous pour contacter l'auteur

Centre de Recherche en Transplantation et Immunologie

Institut de transplantation urologie-néphrologie

Faculté de Médecine - Université de Nantes

Abstract

Comment on CRISPR/Cas9-mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse. [EMBO Mol Med. 2016]

Domains

Human health and pathology

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EMMM-8-439.pdf (148.35 Ko)

Origin : Publisher files allowed on an open archive

Sylvie Le Bihan : Connect in order to contact the contributor

https://www.hal.inserm.fr/inserm-02150381

Submitted on : Friday, June 7, 2019-11:30:53 AM

Last modification on : Wednesday, May 24, 2023-4:14:01 PM

Dates and versions

inserm-02150381 , version 1 (07-06-2019)

Identifiers

HAL Id : inserm-02150381 , version 1
DOI : 10.15252/emmm.201606325
PUBMED : 27138565
PUBMEDCENTRAL : PMC5130315

Cite

Tuan Huy Nguyen, Ignacio Anegon. Successful correction of hemophilia by CRISPR/Cas9 genome editing in vivo : delivery vector and immune responses are the key to success. EMBO Molecular Medicine, 2016, 8 (5), pp.439-441. ⟨10.15252/emmm.201606325⟩. ⟨inserm-02150381⟩

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