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Successful correction of hemophilia by CRISPR/Cas9 genome editing in vivo : delivery vector and immune responses are the key to success

Abstract : Comment on CRISPR/Cas9-mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse. [EMBO Mol Med. 2016]
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Tuan Nguyen, Ignacio Anegon. Successful correction of hemophilia by CRISPR/Cas9 genome editing in vivo : delivery vector and immune responses are the key to success. EMBO Molecular Medicine, Wiley Open Access, 2016, 8 (5), pp.439-441. ⟨10.15252/emmm.201606325⟩. ⟨inserm-02150381⟩

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