Successful correction of hemophilia by CRISPR/Cas9 genome editing in vivo : delivery vector and immune responses are the key to success

Tuan Nguyen; Ignacio Anegon

Successful correction of hemophilia by CRISPR/Cas9 genome editing in vivo : delivery vector and immune responses are the key to success

Tuan Nguyen ^{1, 2, 3} Ignacio Anegon ^{1, 2, 3, *}

* Corresponding author

1 U1064 Inserm - CRTI - Centre de Recherche en Transplantation et Immunologie

2 ITUN - Institut de transplantation urologie-néphrologie

3 Faculté de Médecine - Université de Nantes

Abstract : Comment on CRISPR/Cas9-mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse. [EMBO Mol Med. 2016]

Document type :

Journal articles

Domain :

Life Sciences [q-bio] / Human health and pathology

Complete list of metadatas

Cited literature [15 references] Display Hide Download

https://www.hal.inserm.fr/inserm-02150381
Contributor : Ana Paula Dutra Azevedo <>
Submitted on : Friday, June 7, 2019 - 11:30:53 AM
Last modification on : Saturday, June 8, 2019 - 1:25:37 AM

EMMM-8-439.pdf

Publisher files allowed on an open archive

Successful correction of hemophilia by CRISPR/Cas9 genome editing in vivo : delivery vector and immune responses are the key to success

File

Identifiers

Collections

Citation

Export

Metrics

53

33

Contact

Successful correction of hemophilia by CRISPR/Cas9 genome editing in vivo : delivery vector and immune responses are the key to success

File

Identifiers

Collections

Citation

Export

Share

Metrics

53

33

Contact