Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction, J. Exp. Med, vol.192, pp.393-404, 2000. ,
Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis, J. Neurol. Sci, vol.62, pp.219-232, 1983. ,
Expanded CD8 T-cell sharing between periphery and CNS in multiple sclerosis, Ann. Clin. Transl. Neurol, vol.2, pp.609-622, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01200787
Multiple sclerosis: T-cell receptor expression in distinct brain regions, Brain J. Neurol, vol.130, pp.2789-2799, 2007. ,
DOI : 10.1093/brain/awm214
URL : https://academic.oup.com/brain/article-pdf/130/11/2789/940443/awm214.pdf
Oligoclonal myelin-reactive T-cell infiltrates derived from multiple sclerosis lesions are enriched in Th17 cells, Clin. Immunol, vol.130, pp.133-144, 2009. ,
DOI : 10.1016/j.clim.2008.08.030
, CSF enrichment of highly differentiated CD8+ T cells in early multiple sclerosis, vol.123, pp.105-113, 2007.
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis, Am. J. Pathol, vol.172, pp.146-155, 2008. ,
CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC, Eur. J. Immunol, vol.40, pp.2174-2181, 2010. ,
Stepwise development of MAIT cells in mouse and human, PLoS Biol, vol.7, p.54, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00707793
Human MAIT and CD8 cells develop from a pool of type-17 precommitted CD8+ T cells, Blood, vol.119, pp.422-433, 2012. ,
Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells, Blood, vol.117, pp.1250-1259, 2011. ,
DOI : 10.1182/blood-2010-08-303339
URL : http://www.bloodjournal.org/content/bloodjournal/117/4/1250.full.pdf
Recognition of vitamin B metabolites by mucosal-associated invariant T cells, Nat. Commun, vol.4, p.2142, 2013. ,
DOI : 10.1038/ncomms3142
URL : https://www.nature.com/articles/ncomms3142.pdf
Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells, J. Exp. Med, vol.210, pp.2305-2320, 2013. ,
DOI : 10.1084/jem.20130958
URL : http://jem.rupress.org/content/210/11/2305.full.pdf
Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1, Nature, vol.422, pp.164-169, 2003. ,
DOI : 10.1038/nature01433
T-cell activation by transitory neo-antigens derived from distinct microbial pathways, Nature, vol.509, pp.361-365, 2014. ,
DOI : 10.1038/nature13160
MR1 presents microbial vitamin B metabolites to MAIT cells, Nature, 2012. ,
DOI : 10.1038/nature11605
Antimicrobial activity of mucosalassociated invariant T cells, Nat. Immunol, vol.11, pp.701-708, 2010. ,
Polyclonal mucosa-associated invariant T cells have unique innate functions in bacterial infection, Infect. Immun, vol.80, pp.3256-3267, 2012. ,
DOI : 10.1128/iai.00279-12
URL : https://iai.asm.org/content/80/9/3256.full.pdf
Human mucosal associated invariant T cells detect bacterially infected cells, PLoS Biol, vol.8, p.1000407, 2010. ,
DOI : 10.1371/journal.pbio.1000407
URL : https://hal.archives-ouvertes.fr/inserm-00707307
MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection, Proc. Natl. Acad. Sci. U. S. A, 2013. ,
DOI : 10.1073/pnas.1302799110
URL : http://www.pnas.org/content/110/33/E3119.full.pdf
B cells modulate mucosal associated invariant T cell immune responses, Front. Immunol, vol.4, 2014. ,
DOI : 10.3389/fimmu.2013.00511
URL : https://www.frontiersin.org/articles/10.3389/fimmu.2013.00511/pdf
Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCR? repertoire, Nat. Commun, vol.5, 2014. ,
DOI : 10.1038/ncomms4866
URL : https://www.nature.com/articles/ncomms4866.pdf
MAIT cells detect and efficiently lyse bacterially-infected epithelial cells, PLoS Pathog, vol.9, p.1003681, 2013. ,
MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets, Mucosal Immunol, vol.8, pp.429-440, 2015. ,
Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis, Brain J. Neurol, vol.136, pp.2888-2903, 2013. ,
Accumulation of Valpha7.2-Jalpha33 invariant T cells in human autoimmune inflammatory lesions in the nervous system, Int. Immunol, vol.16, pp.223-230, 2004. ,
, , p.8
, + MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis, Eur. J. Immunol, vol.44, pp.3119-3128, 2014.
CD161(high)CD8+ T cells bear pathogenetic potential in multiple sclerosis, Brain J. Neurol, vol.134, pp.542-554, 2011. ,
Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis, Int. Immunol, vol.23, pp.529-535, 2011. ,
Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the Diagnosis of Multiple Sclerosis, Ann. Neurol, vol.50, pp.121-127, 2001. ,
Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald criteria, Ann. Neurol, vol.58, pp.840-846, 2005. ,
Blood-brain barrier-specific properties of a human adult brain endothelial cell line, FASEB J, 2005. ,
Migration of multiple sclerosis lymphocytes through brain endothelium, Arch. Neurol, vol.59, p.391, 2002. ,
Analysis of relative gene expression data using real-time quantitative PCR and the 2(?Delta Delta C(T)) method, Methods San Diego Calif, vol.25, pp.402-408, 2001. ,
Blood CD8+ T cell responses against myelin determinants in multiple sclerosis and healthy individuals, Eur. J. Immunol, vol.38, pp.1889-1899, 2008. ,
,
Circulating mucosal-associated invariant T cell levels and their cytokine levels in healthy adults, Exp. Gerontol, vol.49, pp.47-54, 2014. ,
The decrease in number and change in phenotype of mucosal-associated invariant T cells in the elderly and differences in males and females of reproductive age, Scand. J. Immunol, 2014. ,
The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression, J. Leukoc. Biol, vol.85, pp.88-97, 2009. ,
Molecular mechanisms of T cell co-stimulation and co-inhibition, Nat. Rev. Immunol, vol.13, pp.227-242, 2013. ,
The role of the CD58 locus in multiple sclerosis, Proc. Natl. Acad. Sci. U. S. A, vol.106, pp.5264-5269, 2009. ,
Capture, crawl, cross: the T cell code to breach the blood-brain barriers, Trends Immunol, vol.33, pp.579-589, 2012. ,
Innate Mucosal-associated Invariant T (MAIT) cells are activated in inflammatory bowel diseases, Clin. Exp. Immunol, 2014. ,
Analysis of stem-cell-like properties of human CD161++IL-18R?+ memory CD8+ T cells, Int. Immunol, vol.24, pp.625-636, 2012. ,
Innate signals overcome acquired TCR signaling pathway regulation and govern the fate of human CD161(hi) CD8? + semiinvariant T cells, Blood, vol.118, pp.2752-2762, 2011. ,
IL-18 in patients with multiple sclerosis, Acta Neurol. Scand, vol.104, pp.171-173, 2001. ,
Increased serum levels of interleukin-18 in patients with multiple sclerosis, Neurology, vol.57, pp.342-344, 2001. ,
CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions, Proc. Natl. Acad. Sci. U. S. A, vol.96, pp.6873-6878, 1999. ,
Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions, J. Exp. Med, vol.182, pp.1985-1996, 1995. ,
CD8+ T cells from patients with acute multiple sclerosis display selective increase of adhesiveness in brain venules: a critical role for P-selectin glycoprotein ligand-1, Blood, vol.101, pp.4775-4782, 2003. ,
PSGL-1 is dispensible for the development of active experimental autoimmune encephalomyelitis in SJL/J mice, J. Neuroimmunol, vol.232, pp.207-208, 2011. ,
P-selectin glycoprotein ligand 1 is not required for the development of experimental autoimmune encephalomyelitis in SJL and C57BL/6 mice, J. Immunol, vol.175, pp.1267-1275, 2005. ,
PSGL-1 is not required for development of experimental autoimmune encephalomyelitis, J. Neuroimmunol, vol.166, pp.193-196, 2005. ,
DOI : 10.1016/j.jneuroim.2005.06.001
Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors, J. Immunol, vol.168, pp.1940-1949, 2002. ,
Central nervous system recruitment of effector memory CD8 + T lymphocytes during neuroinflammation is dependent on ?4 integrin, Brain J. Neurol, vol.134, pp.3560-3577, 2011. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00723279
Interleukin-17-secreting T cells in neuromyelitis optica and multiple sclerosis during relapse, J. Clin. Neurosci. Off. J. Neurosurg. Soc. Aust, vol.18, pp.1313-1317, 2011. ,
DOI : 10.1016/j.jocn.2011.01.031
The IL-17A-producing CD8+ T-cell population in psoriatic lesional skin comprises mucosa-associated invariant T cells and conventional T cells, J. Invest. Dermatol, vol.134, pp.2898-2907, 2014. ,